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2D Structure
Also known as: 1146963-51-0, N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-[(1e)-(3-methoxyphenyl)methylidene]acetohydrazide, N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-((1e)-(3-methoxyphenyl)methylidene)acetohydrazide, Refchem:923870, J-147, Unii-z41h3c5bt9
Molecular Formula
C18H17F3N2O2
Molecular Weight
350.3  g/mol
InChI Key
HYMZAYGFKNNHDN-SSDVNMTOSA-N
FDA UNII
Z41H3C5BT9

neurotrophic curcumin derivative compound that has enhanced stability and bioavailability over curcumin
1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide
2.1.2 InChI
InChI=1S/C18H17F3N2O2/c1-12-7-8-16(13(2)9-12)23(17(24)18(19,20)21)22-11-14-5-4-6-15(10-14)25-3/h4-11H,1-3H3/b22-11+
2.1.3 InChI Key
HYMZAYGFKNNHDN-SSDVNMTOSA-N
2.2 Other Identifiers
2.2.1 UNII
Z41H3C5BT9
2.3 Synonyms
2.3.1 MeSH Synonyms

1. J-147

2.3.2 Depositor-Supplied Synonyms

1. 1146963-51-0

2. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-[(1e)-(3-methoxyphenyl)methylidene]acetohydrazide

3. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-((1e)-(3-methoxyphenyl)methylidene)acetohydrazide

4. Refchem:923870

5. J-147

6. Unii-z41h3c5bt9

7. J 147

8. 1807913-16-1

9. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-(3-methoxybenzylidene)acetohydrazide

10. Z41h3c5bt9

11. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n-[(e)-(3-methoxyphenyl)methylideneamino]acetamide

12. Mfcd25976644

13. Acetic Acid, 2,2,2-trifluoro-, 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide

14. 2,2,2-trifluoroacetic Acid 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide

15. Acetic Acid, 2,2,2-trifluoro-, 1-(2,4-dimethylphenyl)-2-((3-methoxyphenyl)methylene)hydrazide

16. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-[(e)-(3-methoxyphenyl)methylene]acetohydrazide

17. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n-((e)-(3-methoxyphenyl)methylideneamino)acetamide

18. Acetic Acid, 2,2,2-trifluoro-, (2e)-1-(2,4-dimethylphenyl)-2-((3-methoxyphenyl)methylene)hydrazide

19. J147 E-isomer

20. Orb1306813

21. Chembl2387144

22. Schembl12995834

23. Schembl31019578

24. Chebi:192601

25. Hymzaygfknnhdn-ssdvnmtosa-n

26. Dtxsid501045787

27. Glxc-04317

28. Hms3886o17

29. Hms6018d11

30. Ex-a2235

31. Hy-13779a

32. S5269

33. Akos024458485

34. Ccg-268030

35. Cs-3688

36. Db13957

37. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-[(e)-(3-methoxyphenyl)methylidene]acetohydrazide

38. Ac-35232

39. As-16718

40. Da-64604

41. Ft102148

42. Hy-13779

43. Cs-0979300

44. A11910

45. J-147?

46. (e)-n-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-(3-methoxybenzylidene)acetohydrazide

47. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-[(3-methoxyphenyl)methylidene]acetohydrazide

48. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n-[(3-methoxyphenyl)methyleneamino]acetamide

49. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n-[(e)-(3-methoxyphenyl)methyleneamino]acetamide

50. N-(2,4-dimethylphenyl)-2,2,2-triluoro-n-[(e)-(3-methoxyphenyl)methylideneamino]acetamide

2.4 Create Date
2009-05-04
3 Chemical and Physical Properties
Molecular Weight 350.3 g/mol
Molecular Formula C18H17F3N2O2
XLogP34.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area41.9
Heavy Atom Count25
Formal Charge0
Complexity481
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1