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Chemistry

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Also known as: 1146963-51-0, N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-[(1e)-(3-methoxyphenyl)methylidene]acetohydrazide, N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-((1e)-(3-methoxyphenyl)methylidene)acetohydrazide, Refchem:923870, J-147, Unii-z41h3c5bt9
Molecular Formula
C18H17F3N2O2
Molecular Weight
350.3  g/mol
InChI Key
HYMZAYGFKNNHDN-SSDVNMTOSA-N
FDA UNII
Z41H3C5BT9

J147
neurotrophic curcumin derivative compound that has enhanced stability and bioavailability over curcumin
1 2D Structure

J147

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide
2.1.2 InChI
InChI=1S/C18H17F3N2O2/c1-12-7-8-16(13(2)9-12)23(17(24)18(19,20)21)22-11-14-5-4-6-15(10-14)25-3/h4-11H,1-3H3/b22-11+
2.1.3 InChI Key
HYMZAYGFKNNHDN-SSDVNMTOSA-N
2.2 Other Identifiers
2.2.1 UNII
Z41H3C5BT9
2.3 Synonyms
2.3.1 MeSH Synonyms

1. J-147

2.3.2 Depositor-Supplied Synonyms

1. 1146963-51-0

2. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-[(1e)-(3-methoxyphenyl)methylidene]acetohydrazide

3. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-((1e)-(3-methoxyphenyl)methylidene)acetohydrazide

4. Refchem:923870

5. J-147

6. Unii-z41h3c5bt9

7. J 147

8. 1807913-16-1

9. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-(3-methoxybenzylidene)acetohydrazide

10. Z41h3c5bt9

11. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n-[(e)-(3-methoxyphenyl)methylideneamino]acetamide

12. Mfcd25976644

13. Acetic Acid, 2,2,2-trifluoro-, 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide

14. 2,2,2-trifluoroacetic Acid 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide

15. Acetic Acid, 2,2,2-trifluoro-, 1-(2,4-dimethylphenyl)-2-((3-methoxyphenyl)methylene)hydrazide

16. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-[(e)-(3-methoxyphenyl)methylene]acetohydrazide

17. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n-((e)-(3-methoxyphenyl)methylideneamino)acetamide

18. Acetic Acid, 2,2,2-trifluoro-, (2e)-1-(2,4-dimethylphenyl)-2-((3-methoxyphenyl)methylene)hydrazide

19. J147 E-isomer

20. Orb1306813

21. Chembl2387144

22. Schembl12995834

23. Schembl31019578

24. Chebi:192601

25. Hymzaygfknnhdn-ssdvnmtosa-n

26. Dtxsid501045787

27. Glxc-04317

28. Hms3886o17

29. Hms6018d11

30. Ex-a2235

31. Hy-13779a

32. S5269

33. Akos024458485

34. Ccg-268030

35. Cs-3688

36. Db13957

37. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-[(e)-(3-methoxyphenyl)methylidene]acetohydrazide

38. Ac-35232

39. As-16718

40. Da-64604

41. Ft102148

42. Hy-13779

43. Cs-0979300

44. A11910

45. J-147?

46. (e)-n-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-(3-methoxybenzylidene)acetohydrazide

47. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-[(3-methoxyphenyl)methylidene]acetohydrazide

48. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n-[(3-methoxyphenyl)methyleneamino]acetamide

49. N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n-[(e)-(3-methoxyphenyl)methyleneamino]acetamide

50. N-(2,4-dimethylphenyl)-2,2,2-triluoro-n-[(e)-(3-methoxyphenyl)methylideneamino]acetamide

2.4 Create Date
2009-05-04
3 Chemical and Physical Properties
Molecular Weight 350.3 g/mol
Molecular Formula C18H17F3N2O2
XLogP34.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area41.9
Heavy Atom Count25
Formal Charge0
Complexity481
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

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PharmaCompass offers a list of J147 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right J147 manufacturer or J147 supplier for your needs.

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API | Excipient name

J147

Synonyms

1146963-51-0, N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-[(1e)-(3-methoxyphenyl)methylidene]acetohydrazide, N-(2,4-dimethylphenyl)-2,2,2-trifluoro-n'-((1e)-(3-methoxyphenyl)methylidene)acetohydrazide, Refchem:923870, J-147, Unii-z41h3c5bt9

Cas Number

1807913-16-1

Unique Ingredient Identifier (UNII)

Z41H3C5BT9

About J147

neurotrophic curcumin derivative compound that has enhanced stability and bioavailability over curcumin

J147 Manufacturers

A J147 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of J147, including repackagers and relabelers. The FDA regulates J147 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. J147 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

J147 Suppliers

A J147 supplier is an individual or a company that provides J147 active pharmaceutical ingredient (API) or J147 finished formulations upon request. The J147 suppliers may include J147 API manufacturers, exporters, distributors and traders.

J147 GMP

J147 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of J147 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right J147 GMP manufacturer or J147 GMP API supplier for your needs.

J147 CoA

A J147 CoA (Certificate of Analysis) is a formal document that attests to J147's compliance with J147 specifications and serves as a tool for batch-level quality control.

J147 CoA mostly includes findings from lab analyses of a specific batch. For each J147 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

J147 may be tested according to a variety of international standards, such as European Pharmacopoeia (J147 EP), J147 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (J147 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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