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Technical details about DSSTox_CID_3388, learn more about the structure, uses, toxicity, action, side effects and more

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2D Structure
Also known as:
Molecular Formula
C17H20N4S
Molecular Weight
312.4  g/mol
InChI Key
WXPNDRBBWZMPQG-UHFFFAOYSA-N

1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[3,2-c][1,5]benzodiazepine
2.1.2 InChI
InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3
2.1.3 InChI Key
WXPNDRBBWZMPQG-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=CC2=C(NC3=CC=CC=C3N=C2S1)N4CCN(CC4)C
2.1.5 Isomeric SMILES
CC1=CC2=C(NC3=CC=CC=C3N=C2S1)N4CCN(CC4)C
2.2 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 312.4 g/mol
Molecular Formula C17H20N4S
XLogP32.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass312.14086783 g/mol
Monoisotopic Mass312.14086783 g/mol
Topological Polar Surface Area56.2 A^2
Heavy Atom Count22
Formal Charge0
Complexity543
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 8  
Drug NameOlanzapine
PubMed HealthOlanzapine
Drug ClassesAntipsychotic
Drug LabelOlanzapine is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresponds to a...
Active IngredientOlanzapine
Dosage FormTablet; Injectable; Tablet, orally disintegrating
Routeoral; Oral; Intramuscular
Strength2.5mg; 10mg/vial; 7.5mg; 15mg; 5mg; 10mg; 20mg
Market StatusTentative Approval; Prescription
CompanyMylan Pharms; Apotex; Aurobindo Pharma; Sun Pharm Inds; Torrent Pharms; Barr Labs; Sandoz; Par Pharm; Roxane; Teva Pharms; Macleods Pharms; Jubilant Generics; Luitpold; Dr Reddys Labs; Orchid Hlthcare; Mylan

2 of 8  
Drug NameSymbyax
PubMed HealthOlanzapine/Fluoxetine (By mouth)
Drug ClassesAntidepressant, Antipsychotic
Active IngredientFluoxetine hydrochloride; olanzapine
Dosage FormCapsule
RouteOral
Strengtheq 50mg base; eq 6mg base; eq 12mg base; eq 3mg base; eq 25mg base
Market StatusPrescription
CompanyLilly

3 of 8  
Drug NameZyprexa
Drug LabelZYPREXA (olanzapine) is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresp...
Active IngredientOlanzapine
Dosage FormTablet; Injectable
RouteOral; Intramuscular
Strength2.5mg; 10mg/vial; 7.5mg; 15mg; 5mg; 10mg; 20mg
Market StatusPrescription
CompanyLilly

4 of 8  
Drug NameZyprexa zydis
Drug LabelZYPREXA (olanzapine) is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresp...
Active IngredientOlanzapine
Dosage FormTablet, orally disintegrating
RouteOral
Strength15mg; 5mg; 10mg; 20mg
Market StatusPrescription
CompanyLilly

5 of 8  
Drug NameOlanzapine
PubMed HealthOlanzapine
Drug ClassesAntipsychotic
Drug LabelOlanzapine is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresponds to a...
Active IngredientOlanzapine
Dosage FormTablet; Injectable; Tablet, orally disintegrating
Routeoral; Oral; Intramuscular
Strength2.5mg; 10mg/vial; 7.5mg; 15mg; 5mg; 10mg; 20mg
Market StatusTentative Approval; Prescription
CompanyMylan Pharms; Apotex; Aurobindo Pharma; Sun Pharm Inds; Torrent Pharms; Barr Labs; Sandoz; Par Pharm; Roxane; Teva Pharms; Macleods Pharms; Jubilant Generics; Luitpold; Dr Reddys Labs; Orchid Hlthcare; Mylan

6 of 8  
Drug NameSymbyax
PubMed HealthOlanzapine/Fluoxetine (By mouth)
Drug ClassesAntidepressant, Antipsychotic
Active IngredientFluoxetine hydrochloride; olanzapine
Dosage FormCapsule
RouteOral
Strengtheq 50mg base; eq 6mg base; eq 12mg base; eq 3mg base; eq 25mg base
Market StatusPrescription
CompanyLilly

7 of 8  
Drug NameZyprexa
Drug LabelZYPREXA (olanzapine) is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresp...
Active IngredientOlanzapine
Dosage FormTablet; Injectable
RouteOral; Intramuscular
Strength2.5mg; 10mg/vial; 7.5mg; 15mg; 5mg; 10mg; 20mg
Market StatusPrescription
CompanyLilly

8 of 8  
Drug NameZyprexa zydis
Drug LabelZYPREXA (olanzapine) is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresp...
Active IngredientOlanzapine
Dosage FormTablet, orally disintegrating
RouteOral
Strength15mg; 5mg; 10mg; 20mg
Market StatusPrescription
CompanyLilly

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