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    Company profile for SemaThera Inc

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    SEMATHERA INC

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    SemaThera develops novel inhibitors against semaphorin 3A (SEMA 3A) for prevention and reversal of diabetic macular edema (DME). SEMA 3A is a soluble protein that promotes vascular leakage and contributes to diabetes-related macular edema. Its levels are significantly elevated in the vitreous of patients with DME as well as in several other vascular diseases of the retina. Importantly, SEMA 3A levels rise in the early stages o...
    SemaThera develops novel inhibitors against semaphorin 3A (SEMA 3A) for prevention and reversal of diabetic macular edema (DME). SEMA 3A is a soluble protein that promotes vascular leakage and contributes to diabetes-related macular edema. Its levels are significantly elevated in the vitreous of patients with DME as well as in several other vascular diseases of the retina. Importantly, SEMA 3A levels rise in the early stages of DME, while VEGF levels are still as low as in non-diabetic controls. Inhibiting SEMA 3A with SemaThera’s biological inhibitors has shown robust pre-clinical efficacy in preventing retinal vascular leakage, inflammation, apoptosis and pathological cytoskeleton remodelling.
    veranova-m-2024-04-22

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    SemaThera Inc
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    Canada
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    800-1 Westmount Square, Montreal, Québec Canada, H3Z 2P9
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    enquiries@pharmacompass.com
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    https://semathera.com/
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    veranova-m-2024-04-22

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