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1. Calcort
2. Dezacor
3. Emflaza
4. Zamene
1. 14484-47-0
2. Azacort
3. Calcort
4. Oxazacort
5. Flantadin
6. Emflaza
7. Cortax
8. Deflan
9. Mdl 458
10. Mdl-458
11. L-5458
12. Kr5yz6ae4b
13. Mdl458
14. Dezacor
15. Lantadin
16. Dsstox_cid_378
17. Dsstox_rid_75552
18. Dsstox_gsid_20378
19. 2-((6ar,6bs,7s,8as,8bs,11ar,12as,12bs)-7-hydroxy-6a,8a,10-trimethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bh-naphtho[2',1':4,5]indeno[1,2-d]oxazol-8b-yl)-2-oxoethyl Acetate
20. Deflazacortum
21. Decortil
22. Deflanil
23. Enzocort
24. Deflazacort (calcort)
25. 2-[(4ar,4bs,5s,6as,6bs,9ar,10as,10bs)-5-hydroxy-4a,6a,8-trimethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bh-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-6b-yl]-2-oxoethyl Acetate
26. Cas-14484-47-0
27. Dl-458-it
28. Unii-kr5yz6ae4b
29. Deflazacortum [inn-latin]
30. Deflazacort [usan:inn:ban]
31. Einecs 238-483-7
32. Emflaza (tn)
33. Mfcd00866106
34. Deflazacort [mi]
35. Deflazacort [inn]
36. Deflazacort (usan/inn)
37. Deflazacort [usan]
38. Schembl4018
39. Deflazacort [mart.]
40. Deflazacort [usp-rs]
41. Deflazacort [who-dd]
42. Dl-458it
43. Gtpl9477
44. Chembl1201891
45. Dtxsid9020378
46. Deflazacort, >=98% (hplc)
47. Deflazacort [orange Book]
48. Chebi:135720
49. Hms3714d15
50. Bcp08474
51. Zinc4212809
52. Tox21_112506
53. Tox21_301415
54. Bbl036672
55. S1888
56. Stl559051
57. Akos015895199
58. Tox21_112506_1
59. Ccg-220817
60. Db11921
61. Ks-1158
62. Ncgc00255189-01
63. Ncgc00263521-01
64. 11beta,21-dihydroxy-2'-methyl-5'betah-pregna-1,4-dieno(17,16-d)oxazole-3,20-dione 21-acetate
65. Hy-13609
66. Deflazacort 100 Microg/ml In Acetonitrile
67. D4523
68. D03671
69. T70289
70. Ab01274724-01
71. Ab01274724_02
72. 484d470
73. Q779118
74. Q-101371
75. 3-amino-3-(4-chloro-3-nitro-phenyl)-propionicacid
76. Deflazacort, United States Pharmacopeia (usp) Reference Standard
77. 11b,21-dihydroxy-2'-methyl-5'bh-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 21-acetate
78. (11beta,16beta)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'h-pregna-1,4-dieno(17,16-d)oxazole-3,20-dione
79. [2-[(1s,2s,4r,8s,9s,11s,12s,13r)-11-hydroxy-6,9,13-trimethyl-16-oxo-5-oxa-7-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-6,14,17-trien-8-yl]-2-oxoethyl] Acetate
80. 11.beta.,21-dihydroxy-2'-methyl-5'.beta.h-pregna-1,4-dieno(17,16-d)oxazole-3,20-dione 21-acetate
81. 2-((6ar,6bs,7s,8as,8bs,11ar,12as,12bs)-7-hydroxy-6a,8a,10-trimethyl-4-oxo-2,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1h-naphtho[2',1':4,5]indeno[1,2-d]oxazol-8b-yl)-2-oxoethyl Acetate
82. 5'-beta-h-pregna-1,4-dieno(17,16-d)oxazole-3,20-dione, 11-beta,21-dihydroxy-2'-methyl-, 21-acetate
83. 5'h-pregna-1,4-dieno(17,16-d)oxazole-3,20-dione, 21-(acetyloxy)-11-hydroxy-2'-methyl-, (11.beta.,16.beta.)-
84. 5'h-pregna-1,4-dieno(17,16-d)oxazole-3,20-dione, 21-(acetyloxy)-11-hydroxy-2'-methyl-, (11beta,16beta)-
| Molecular Weight | 441.5 g/mol |
|---|---|
| Molecular Formula | C25H31NO6 |
| XLogP3 | 2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 4 |
| Exact Mass | 441.21513771 g/mol |
| Monoisotopic Mass | 441.21513771 g/mol |
| Topological Polar Surface Area | 102 Ų |
| Heavy Atom Count | 32 |
| Formal Charge | 0 |
| Complexity | 996 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 8 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Deflazacort is indicated for the treatment of Duchenne Muscular Dystrophy (DMD) in patients 2 years of age and older.
Deflazacort exerts anti-inflammatory activity in DMD, likely improving various symptoms, including muscle weakness and cardiorespiratory symptoms in addition to delaying their onset. This allows for an increased quality of life and prevents the necessity for surgical procedures, such as those for scoliosis, which is associated with DMD. Studies showed significant preservation of muscle mass in patients generally treated with 0.9 mg/kg/day of deflazacort compared to a control group. The following findings are based on clinical studies using deflazacort on a long term basis: **Effects on muscle strength** At age 16, individuals treated with long-term deflazacort had 63 4% score in muscle strength compared to a mean muscle strength score of 31 3% for control patients. Significant improvements in climbing stairs and rising from a supine position were also seen in patients taking deflazacort. **Effects on ambulation** Ambulation was significantly higher by 12 years of age and 18 years of age in patients taking deflazacort when compared with the control group. The control group showed a mean loss of ambulation of 2 years sooner than with deflazacort treatment. **Effects on cardiac function** Mean left ventricular ejection fraction (a measure of cardiac function) was higher in patients treated with deflazacort over the long term. Preservation of cardiac function was demonstrated by a mean difference in ejection fraction of about 7%, favoring study groups taking deflazacort over control groups. **Effects on spinal alignment** Children treated with deflazacort also significantly lowered the rate and severity of scoliosis and eliminated the need for scoliosis surgery after long-term treatment.
Anti-Inflammatory Agents
Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)
Immunosuppressive Agents
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging. (See all compounds classified as Immunosuppressive Agents.)
H02AB13
S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355
H - Systemic hormonal preparations, excl. sex hormones and insulins
H02 - Corticosteroids for systemic use
H02A - Corticosteroids for systemic use, plain
H02AB - Glucocorticoids
H02AB13 - Deflazacort
Absorption
Deflazacort is rapidly absorbed after oral administration with peak concentration occurring within 1-2 hours. One pharmacokinetic study determined an AUC (area under the curve) of 280 ng/ml h. The bioavailability of both the oral suspension and tablet are similar. In clinical studies, coadministration of deflazacort crushed with food or applesauce did not affect absorption or bioavailability.
Route of Elimination
Urinary excretion is the major route of deflazacort elimination, accounting for about about 70% of the excreted dose. The remainder of the dose (about 30%) is excreted in the feces. Elimination is almost completed by 24 hours post-dose. 21-deflazacort makes up about 18% of the eliminated drug in the urine.
Volume of Distribution
One study determined the volume of distribution to be 204 84 L.
Clearance
114 27 L/h, according to one noncompartmental pharmacokinetic study. The clearance of corticosteroids is enhanced in hypothyroid patients and increased in patients with hyperthyroidism. Dosing adjustments may be considered according to thyroid status. A study of corticosteroid clearance was performed in patients with a creatinine clearance of 15 mL/min or less, and determined that the active metabolite of deflazacort, 21-deflazacort was similar to that in patients with normal renal clearance.
After oral ingestion, deflazacort is deacetylated at position 21 by plasma esterases, producing the active metabolite 21-deflazacort. 21-deflazacort is then further metabolized by CYP3A4 to inactive metabolite products. Deflazacort 21-OH metabolism is extensive. The metabolite of deflazacort-21-OH is deflazacort 6-beta-OH.
The half-life of deflazacort ranges from 1.1 to 1.9 h
Deflazacort is a corticosteroid prodrug with an active metabolite, 21-deflazacort, which binds to the glucocorticoid receptor to exert anti-inflammatory and immunosuppressive effects on the body. The exact mechanism by which deflazacort exerts its therapeutic effects in patients with DMD is unknown but likely occurs via its anti-inflammatory activities.
GDUFA
DMF Review : Complete
Rev. Date : 2023-12-20
Pay. Date : 2023-11-22
DMF Number : 38936
Submission : 2023-10-05
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2021-11-05
Pay. Date : 2021-11-02
DMF Number : 24691
Submission : 2011-03-02
Status : Active
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 4922
Submission : 1983-03-17
Status : Inactive
Type : II

GDUFA
DMF Review : Complete
Rev. Date : 2023-07-11
Pay. Date : 2023-05-19
DMF Number : 38357
Submission : 2023-05-19
Status : Active
Type : II

GDUFA
DMF Review : Complete
Rev. Date : 2023-03-08
Pay. Date : 2023-03-06
DMF Number : 30313
Submission : 2016-03-02
Status : Active
Type : II

GDUFA
DMF Review : Complete
Rev. Date : 2021-07-28
Pay. Date : 2021-05-26
DMF Number : 35535
Submission : 2021-04-26
Status : Active
Type : II

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API Imports and Exports
| Importing Country | Total Quantity (KGS) |
Average Price (USD/KGS) |
Number of Transactions |
|---|
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Regulatory Info : RX
Registration Country : USA
Brand Name : PYQUVI
Dosage Form : SUSPENSION;ORAL
Dosage Strength : 22.75MG/ML
Packaging :
Approval Date : 2025-06-30
Application Number : 219417
Regulatory Info : RX
Registration Country : USA
Regulatory Info : Authorized
Registration Country : Spain
Brand Name : Deflazacort Pensa
Dosage Form : Tablet
Dosage Strength : 30MG
Packaging :
Approval Date : 2011-04-13
Application Number : 73882
Regulatory Info : Authorized
Registration Country : Spain
Regulatory Info : Suspensed
Registration Country : Spain
Brand Name : Deflazacort Pensa
Dosage Form : Tablet
Dosage Strength : 6MG
Packaging :
Approval Date : 2011-04-13
Application Number : 73883
Regulatory Info : Suspensed
Registration Country : Spain
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Regulatory Info : RX
Registration Country : USA
Brand Name : EMFLAZA
Dosage Form : TABLET;ORAL
Dosage Strength : 6MG
Packaging :
Approval Date : 2017-02-09
Application Number : 208684
Regulatory Info : RX
Registration Country : USA

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Regulatory Info : RX
Registration Country : USA
Brand Name : EMFLAZA
Dosage Form : TABLET;ORAL
Dosage Strength : 18MG
Packaging :
Approval Date : 2017-02-09
Application Number : 208684
Regulatory Info : RX
Registration Country : USA

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Regulatory Info : RX
Registration Country : USA
Brand Name : EMFLAZA
Dosage Form : TABLET;ORAL
Dosage Strength : 30MG
Packaging :
Approval Date : 2017-02-09
Application Number : 208684
Regulatory Info : RX
Registration Country : USA

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Regulatory Info : RX
Registration Country : USA
Brand Name : EMFLAZA
Dosage Form : TABLET;ORAL
Dosage Strength : 36MG
Packaging :
Approval Date : 2017-02-09
Application Number : 208684
Regulatory Info : RX
Registration Country : USA

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Regulatory Info : RX
Registration Country : USA
Brand Name : EMFLAZA
Dosage Form : SUSPENSION;ORAL
Dosage Strength : 22.75MG/ML
Packaging :
Approval Date : 2017-02-09
Application Number : 208685
Regulatory Info : RX
Registration Country : USA

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Regulatory Info : RX
Registration Country : USA
Brand Name : DEFLAZACORT
Dosage Form : TABLET;ORAL
Dosage Strength : 6MG
Packaging :
Approval Date : 2024-11-05
Application Number : 216720
Regulatory Info : RX
Registration Country : USA

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Regulatory Info : RX
Registration Country : USA
Brand Name : DEFLAZACORT
Dosage Form : TABLET;ORAL
Dosage Strength : 18MG
Packaging :
Approval Date : 2024-11-05
Application Number : 216720
Regulatory Info : RX
Registration Country : USA

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]RLD : No
TE Code : AB
Brand Name : PYQUVI
Dosage Form : SUSPENSION;ORAL
Dosage Strength : 22.75MG/ML
Approval Date : 2025-06-30
Application Number : 219417
RX/OTC/DISCN : RX
RLD : No
TE Code : AB
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RLD : No
TE Code : AB
Brand Name : DEFLAZACORT
Dosage Form : TABLET;ORAL
Dosage Strength : 18MG
Approval Date : 2024-02-09
Application Number : 217123
RX/OTC/DISCN : RX
RLD : No
TE Code : AB

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RLD : No
TE Code : AB
Brand Name : DEFLAZACORT
Dosage Form : TABLET;ORAL
Dosage Strength : 30MG
Approval Date : 2024-02-09
Application Number : 217123
RX/OTC/DISCN : RX
RLD : No
TE Code : AB

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RLD : No
TE Code : AB
Brand Name : DEFLAZACORT
Dosage Form : TABLET;ORAL
Dosage Strength : 36MG
Approval Date : 2024-02-09
Application Number : 217123
RX/OTC/DISCN : RX
RLD : No
TE Code : AB

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RLD : Yes
TE Code : AB
Brand Name : EMFLAZA
Dosage Form : TABLET;ORAL
Dosage Strength : 6MG
Approval Date : 2017-02-09
Application Number : 208684
RX/OTC/DISCN : RX
RLD : Yes
TE Code : AB

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RLD : No
TE Code : AB
Brand Name : DEFLAZACORT
Dosage Form : TABLET;ORAL
Dosage Strength : 6MG
Approval Date : 2025-03-18
Application Number : 217741
RX/OTC/DISCN : RX
RLD : No
TE Code : AB

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RLD : No
TE Code : AB
Brand Name : DEFLAZACORT
Dosage Form : TABLET;ORAL
Dosage Strength : 18MG
Approval Date : 2025-03-18
Application Number : 217741
RX/OTC/DISCN : RX
RLD : No
TE Code : AB

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RLD : No
TE Code : AB
Brand Name : DEFLAZACORT
Dosage Form : TABLET;ORAL
Dosage Strength : 30MG
Approval Date : 2025-03-18
Application Number : 217741
RX/OTC/DISCN : RX
RLD : No
TE Code : AB

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RLD : No
TE Code : AB
Brand Name : JAYTHARI
Dosage Form : TABLET;ORAL
Dosage Strength : 30MG
Approval Date : 2025-04-08
Application Number : 219254
RX/OTC/DISCN : RX
RLD : No
TE Code : AB

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RLD : No
TE Code : AB
Brand Name : JAYTHARI
Dosage Form : TABLET;ORAL
Dosage Strength : 36MG
Approval Date : 2025-04-08
Application Number : 219254
RX/OTC/DISCN : RX
RLD : No
TE Code : AB

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Regulatory Info : Authorized
Registration Country : Spain
Brand Name : Deflazacort Pensa
Dosage Form : Tablet
Dosage Strength : 30MG
Packaging :
Approval Date : 2011-04-13
Application Number : 73882
Regulatory Info : Authorized
Registration Country : Spain
Regulatory Info : Suspensed
Registration Country : Spain
Brand Name : Deflazacort Pensa
Dosage Form : Tablet
Dosage Strength : 6MG
Packaging :
Approval Date : 2011-04-13
Application Number : 73883
Regulatory Info : Suspensed
Registration Country : Spain
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Regulatory Info : Authorized
Registration Country : Spain
Brand Name : Deflazacort Cinfa
Dosage Form : Tablet
Dosage Strength : 30MG
Packaging :
Approval Date : 2011-04-13
Application Number : 73873
Regulatory Info : Authorized
Registration Country : Spain

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Regulatory Info : Authorized
Registration Country : Spain
Brand Name : Dezacor
Dosage Form : Tablet
Dosage Strength : 30MG
Packaging :
Approval Date : 1990-03-01
Application Number : 57816
Regulatory Info : Authorized
Registration Country : Spain

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Regulatory Info : Authorized
Registration Country : Spain
Brand Name : Defal
Dosage Form : Tablet
Dosage Strength : 6MG
Packaging :
Approval Date : 2008-02-22
Application Number : 69632
Regulatory Info : Authorized
Registration Country : Spain

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Regulatory Info : Authorized
Registration Country : Spain
Brand Name : Deflazacort Normon
Dosage Form : Tablet
Dosage Strength : 30MG
Packaging :
Approval Date : 2011-04-12
Application Number : 73850
Regulatory Info : Authorized
Registration Country : Spain

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Regulatory Info : Authorized
Registration Country : Spain
Brand Name : Zamene
Dosage Form : Tablet
Dosage Strength : 30MG
Packaging :
Approval Date : 1990-07-01
Application Number : 58655
Regulatory Info : Authorized
Registration Country : Spain

Regulatory Info :
Registration Country : Italy
Brand Name : Flantadin
Dosage Form :
Dosage Strength : 10 Cpr 6 Mg
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Italy

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Regulatory Info :
Registration Country : Italy
Brand Name : Deflan
Dosage Form :
Dosage Strength : 10 Cpr 30 Mg
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Italy

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Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Regulatory Info : Approved
Registration Country : Sweden
Brand Name : Deflazacort Xgx Pharma
Dosage Form : Tablet
Dosage Strength : 30mg
Packaging :
Approval Date : 19/11/2021
Application Number : 20190102000108
Regulatory Info : Approved
Registration Country : Sweden

Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
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Regulatory Info :
Registration Country : India
Brand Name :
Dosage Form : Tablet
Dosage Strength : 30MG
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : India

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Packaging :
Regulatory Info :
Dosage : Tablet
Dosage Strength : 30MG
Brand Name :
Approval Date :
Application Number :
Registration Country : India

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Regulatory Info :
Registration Country : India
Brand Name : Delflaz 6
Dosage Form : Tablet
Dosage Strength : 6MG
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : India

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Packaging :
Regulatory Info :
Dosage : Tablet
Dosage Strength : 6MG
Brand Name : Delflaz 6
Approval Date :
Application Number :
Registration Country : India

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Regulatory Info :
Registration Country : India
Brand Name : CORTOSEPT-6
Dosage Form : Tablet
Dosage Strength : 6MG
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : India

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Packaging :
Regulatory Info :
Dosage : Tablet
Dosage Strength : 6MG
Brand Name : CORTOSEPT-6
Approval Date :
Application Number :
Registration Country : India

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Regulatory Info : Generic
Registration Country : India
Brand Name :
Dosage Form : TABLET
Dosage Strength :
Packaging :
Approval Date :
Application Number :
Regulatory Info : Generic
Registration Country : India

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Packaging :
Regulatory Info : Generic
Dosage : TABLET
Dosage Strength :
Brand Name :
Approval Date :
Application Number :
Registration Country : India

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Regulatory Info : Generic
Registration Country : South Korea
Brand Name : DEFLA
Dosage Form : TABLET
Dosage Strength : 6MG
Packaging : 100T
Approval Date :
Application Number :
Regulatory Info : Generic
Registration Country : South Korea

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Packaging : 100T
Regulatory Info : Generic
Dosage : TABLET
Dosage Strength : 6MG
Brand Name : DEFLA
Approval Date :
Application Number :
Registration Country : South Korea

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Regulatory Info :
Registration Country : India
Brand Name :
Dosage Form : Tablet
Dosage Strength : 6MG
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : India

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Regulatory Info :
Dosage : Tablet
Dosage Strength : 6MG
Brand Name :
Approval Date :
Application Number :
Registration Country : India

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Regulatory Info :
Registration Country : India
Brand Name : Inflacort
Dosage Form : Tablet
Dosage Strength : 6MG
Packaging : 1x10
Approval Date :
Application Number :
Regulatory Info :
Registration Country : India

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Packaging : 1x10
Regulatory Info :
Dosage : Tablet
Dosage Strength : 6MG
Brand Name : Inflacort
Approval Date :
Application Number :
Registration Country : India

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Regulatory Info :
Registration Country : India
Brand Name :
Dosage Form : Tablet
Dosage Strength : 6MG
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : India

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Packaging :
Regulatory Info :
Dosage : Tablet
Dosage Strength : 6MG
Brand Name :
Approval Date :
Application Number :
Registration Country : India

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Regulatory Info : Generic
Registration Country : India
Brand Name : Cerdef
Dosage Form : TABLET
Dosage Strength : 6MG
Packaging : 10 x 10 Alu Alu
Approval Date :
Application Number :
Regulatory Info : Generic
Registration Country : India

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Packaging : 10 x 10 Alu Alu
Regulatory Info : Generic
Dosage : TABLET
Dosage Strength : 6MG
Brand Name : Cerdef
Approval Date :
Application Number :
Registration Country : India

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Regulatory Info :
Registration Country : India
Brand Name :
Dosage Form : Syrup
Dosage Strength : 6MG
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : India

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Dosage : Syrup
Dosage Strength : 6MG
Brand Name :
Approval Date :
Application Number :
Registration Country : India

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]DRUG PRODUCT COMPOSITIONS
Related Excipient Companies
Excipients by Applications
Global Sales Information
Company : Ptc Therapeutic
Deflazacort
Drug Cost (USD) : 15,369,330
Year : 2023
Prescribers : 99
Prescriptions : 1181

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Product Web Link
Virtual Booth
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Company : Ptc Therapeutic
Deflazacort
Drug Cost (USD) : 11,065,608
Year : 2022
Prescribers : 94
Prescriptions : 1069

Portfolio PDF
Product Web Link
Virtual Booth
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Website
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Company : Ptc Therapeutic
Deflazacort
Drug Cost (USD) : 7,596,448
Year : 2021
Prescribers : 73
Prescriptions : 862

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Virtual Booth
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Website
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Company : Ptc Therapeutic
Deflazacort
Drug Cost (USD) : 5,876,991
Year : 2020
Prescribers : 61
Prescriptions : 748

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Product Web Link
Virtual Booth
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Company : Ptc Therapeutic
Deflazacort
Drug Cost (USD) : 2,645,232
Year : 2019
Prescribers : 50
Prescriptions : 353

Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Company : Marathon/Ptc Th
Deflazacort
Drug Cost (USD) : 1,222,583
Year : 2019
Prescribers : 43
Prescriptions : 177

Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Company : Marathon/Ptc Th
Deflazacort
Drug Cost (USD) : 3,523,041
Year : 2018
Prescribers : 56
Prescriptions : 509

Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]LAB.GUIDOTTI SpA
Dosage Form :
Dosage Strength : 10 Cpr 6 Mg
Price Per Pack (Euro) : 6.59
Published in :
Country : Italy
RX/OTC/DISCN : Class C

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Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
LAB.GUIDOTTI SpA
Dosage Form :
Dosage Strength : 10 Cpr 30 Mg
Price Per Pack (Euro) : 20.02
Published in :
Country : Italy
RX/OTC/DISCN : Class C

Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
LAB.GUIDOTTI SpA
Dosage Form :
Dosage Strength : Gtt Os 13 Ml 22.75 Mg/Ml
Price Per Pack (Euro) : 17.91
Published in :
Country : Italy
RX/OTC/DISCN : Class C

Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
TEOFARMA Srl
Dosage Form :
Dosage Strength : 10 Cpr 6 Mg
Price Per Pack (Euro) : 6.59
Published in :
Country : Italy
RX/OTC/DISCN : Class C

Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
TEOFARMA Srl
Dosage Form :
Dosage Strength : 10 Cpr 30 Mg
Price Per Pack (Euro) : 20.02
Published in :
Country : Italy
RX/OTC/DISCN : Class C

Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
TEOFARMA Srl
Dosage Form :
Dosage Strength : Gtt Os 13 Ml 22.75 Mg/Ml
Price Per Pack (Euro) : 17.91
Published in :
Country : Italy
RX/OTC/DISCN : Class C

Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Market Place
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FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]
Patents & EXCLUSIVITIES
REF. STANDARDS & IMPURITIES
ABOUT THIS PAGE
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PharmaCompass offers a list of Deflazacort API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Deflazacort manufacturer or Deflazacort supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Deflazacort manufacturer or Deflazacort supplier.
PharmaCompass also assists you with knowing the Deflazacort API Price utilized in the formulation of products. Deflazacort API Price is not always fixed or binding as the Deflazacort Price is obtained through a variety of data sources. The Deflazacort Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Zamene manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Zamene, including repackagers and relabelers. The FDA regulates Zamene manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Zamene API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Zamene manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Zamene supplier is an individual or a company that provides Zamene active pharmaceutical ingredient (API) or Zamene finished formulations upon request. The Zamene suppliers may include Zamene API manufacturers, exporters, distributors and traders.
click here to find a list of Zamene suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Zamene DMF (Drug Master File) is a document detailing the whole manufacturing process of Zamene active pharmaceutical ingredient (API) in detail. Different forms of Zamene DMFs exist exist since differing nations have different regulations, such as Zamene USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Zamene DMF submitted to regulatory agencies in the US is known as a USDMF. Zamene USDMF includes data on Zamene's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Zamene USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Zamene suppliers with USDMF on PharmaCompass.
A Zamene written confirmation (Zamene WC) is an official document issued by a regulatory agency to a Zamene manufacturer, verifying that the manufacturing facility of a Zamene active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Zamene APIs or Zamene finished pharmaceutical products to another nation, regulatory agencies frequently require a Zamene WC (written confirmation) as part of the regulatory process.
click here to find a list of Zamene suppliers with Written Confirmation (WC) on PharmaCompass.
National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Zamene as an active pharmaceutical ingredient (API).
The FDA updates the NDC directory daily. The NDC numbers for Zamene API and other APIs are published in this directory by the FDA.
The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.
Pharmaceutical companies that manufacture Zamene as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.
The NDC directory also contains data on finished compounded human drug products that contain Zamene and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Zamene NDC to their finished compounded human drug products, they may choose to do so.
click here to find a list of Zamene suppliers with NDC on PharmaCompass.
Zamene Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Zamene GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Zamene GMP manufacturer or Zamene GMP API supplier for your needs.
A Zamene CoA (Certificate of Analysis) is a formal document that attests to Zamene's compliance with Zamene specifications and serves as a tool for batch-level quality control.
Zamene CoA mostly includes findings from lab analyses of a specific batch. For each Zamene CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Zamene may be tested according to a variety of international standards, such as European Pharmacopoeia (Zamene EP), Zamene JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Zamene USP).
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