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    Chemistry

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    Also known as: 33286-22-5, Diltiazem hcl, Cardizem, Dilzem, Dilzene, Masdil
    Molecular Formula
    C22H27ClN2O4S
    Molecular Weight
    451.0  g/mol
    InChI Key
    HDRXZJPWHTXQRI-BHDTVMLSSA-N
    FDA UNII
    OLH94387TE
    Diltiazem Hydrochloride
    A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.
    1 2D Structure

    Diltiazem Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate;hydrochloride
    2.1.2 InChI
    InChI=1S/C22H26N2O4S.ClH/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;/h5-12,20-21H,13-14H2,1-4H3;1H/t20-,21+;/m1./s1
    2.1.3 InChI Key
    HDRXZJPWHTXQRI-BHDTVMLSSA-N
    2.1.4 Canonical SMILES
    CC(=O)OC1C(SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC.Cl
    2.1.5 Isomeric SMILES
    CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    OLH94387TE
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Aldizem

    2. Cardil

    3. Cardizem

    4. Crd 401

    5. Crd-401

    6. Crd401

    7. Dilacor

    8. Dilacor Xr

    9. Dilren

    10. Diltiazem

    11. Diltiazem Malate

    12. Dilzem

    13. Tiazac

    2.3.2 Depositor-Supplied Synonyms

    1. 33286-22-5

    2. Diltiazem Hcl

    3. Cardizem

    4. Dilzem

    5. Dilzene

    6. Masdil

    7. (+)-cis-diltiazem Hydrochloride

    8. Tiazac

    9. Crd-401

    10. Altiazem

    11. Deltazen

    12. Diladel

    13. Dilpral

    14. Dilrene

    15. Tildiem

    16. Adizem

    17. Herbesser

    18. Dilacor

    19. Lacerol

    20. Zilden

    21. Mono-tildiem

    22. Bi-tildiem

    23. Cardizem Cd

    24. Cardizem La

    25. Cardil

    26. Dilren

    27. Dilthiazem Hydrochloride

    28. Diltiazem (hydrochloride)

    29. Diltzac

    30. Cartia

    31. Rg 83606

    32. (2s,3s)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate Hydrochloride

    33. Taztia

    34. Diltiazem Hcl (tiazac)

    35. 103532-26-9

    36. Mls000028432

    37. Olh94387te

    38. Rg 83606 Hcl

    39. Chebi:645509

    40. Anoheal

    41. Nsc-759576

    42. (+)-5-(2-(dimethylamino)ethyl)-cis-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5h)-one Acetate (ester) Monohydrochloride

    43. (2s,3s)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl Acetate Hydrochloride

    44. [(2s,3s)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] Acetate;hydrochloride

    45. 38411-61-9

    46. Dilzicardin

    47. Anginyl

    48. Angitil

    49. Angizem

    50. Britiazim

    51. Calcicard

    52. Calnurs

    53. Cardiazem

    54. Cirilen

    55. Citizen

    56. Clarute

    57. Corazet

    58. Dilatam

    59. Dilatame

    60. Dilcard

    61. Dilgard

    62. Dilicardin

    63. Diltahexal

    64. Diltelan

    65. Diltiasyn

    66. Diltikor

    67. Diltime

    68. Dinisor

    69. Dodexen

    70. Entrydil

    71. Farmabes

    72. Gadoserin

    73. Helsibon

    74. Incoril

    75. Kaltiazen

    76. Levozem

    77. Longazem

    78. Lytelsen

    79. Metazem

    80. Miocardie

    81. Oxycardil

    82. Pazeadin

    83. Pentilzeno

    84. Poltiazem

    85. Presoken

    86. Rg-83606

    87. Smr000058375

    88. Tilazem

    89. Trumsal

    90. Ziruvate

    91. Bruzem

    92. Carzem

    93. Diatal

    94. Dilfar

    95. Dilsal

    96. Diltam

    97. Diltan

    98. Doclis

    99. Dyalac

    100. Etizen

    101. Etyzen

    102. Herben

    103. Kardil

    104. Myonil

    105. Slozen

    106. Tiadil

    107. Tiaves

    108. Ubicor

    109. Zildem

    110. Carex

    111. Coras

    112. Dazil

    113. Dilem

    114. Dilso

    115. Hesor

    116. Tazem

    117. Apo-diltiazem

    118. Iski

    119. Altiazem Retard

    120. Cardizem Retard

    121. Diltiazem Merck

    122. Diltiazem Stada

    123. Diltiazem Verla

    124. Diltiazem-mepha

    125. 33286-22-5 (hcl)

    126. Cardil Retard

    127. Dil-sonaramia

    128. Diltiazem-isis

    129. Dilzem Retard

    130. Dinisor Retard

    131. Myonil Retard

    132. Novo-diltazem

    133. Syn-diltiazem

    134. Tildiem Retard

    135. Diltiazem Basics

    136. Diltiazem-cophar

    137. Mfcd00069252

    138. Uni Masdil

    139. Wl Diltiazem

    140. Altiazem Rr

    141. Cardizem Sr

    142. Diltiazem Awd

    143. Diltiazem Gnr

    144. Diltiazem Msd

    145. Diltiazem-gry

    146. Cirilen Ap

    147. Diltiazem Henning

    148. Diltiazem Upsa

    149. Tildiem Cr

    150. Tildiem La

    151. Adizem-cd

    152. Cartia Xt

    153. Diltan Sr

    154. Diltiazem Eu Rho

    155. Dilzem Rr

    156. Taztia Xt

    157. Viazem Sr

    158. Viazem Xl

    159. Herbesser 60

    160. (2s-cis)-3-acetoxy-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5h)-one Monohydrochloride

    161. [(2s,3s)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] Acetate;hydron;chloride

    162. 1,5-benzothiazepin-4(5h)-one, 3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-, Monohydrochloride, (+)-cis-

    163. Herbesser 90 Sr

    164. Tilazem 90

    165. Diltiazem Chloridrate

    166. Dilatam 120

    167. Tilazem As 60

    168. Tilazem As 90

    169. Dilzereal 90 Retard

    170. Herbesser 180 Sr

    171. Dolizem

    172. Iski-90 Sr

    173. Diltia Xt

    174. Dilt-xr

    175. Dodexen A.p.

    176. Presokin A. P.

    177. Mk-793

    178. Crd 401

    179. Tiazac Extended Release

    180. Sr-01000003042

    181. Einecs 251-443-3

    182. Dilacor Xr Extended Release Capsules

    183. Unii-olh94387te

    184. Milptin

    185. Carzen

    186. Slozem

    187. Crd401

    188. Dilthiazem Hcl

    189. Dov Diltiazem

    190. Uni-masdil

    191. Cardizem Xl

    192. Tiazac Xc

    193. Cardizem (tn)

    194. Prestwick_176

    195. Acetate Hydrochloride

    196. Einecs 253-918-0

    197. Dilacor Xr (tn)

    198. Cartia Xt (tn)

    199. Opera_id_79

    200. Diltiazem Hydrochloride [usan:usp:jan]

    201. Dilt-cd (tn)

    202. (+)-5-(2-(dimethylamino)ethyl)-cis-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5h)-one Acetate Ester Monohydrochloride

    203. 2-[(2s,3s)-3-(acetyloxy)-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-1,5-benzothiazepin-5(2h)-yl]-n,n-dimethylethanaminium Chloride

    204. Chembl1697

    205. Diltiazem Hydrochloride,(s)

    206. Schembl15457

    207. Mls001148257

    208. Mls002222179

    209. Diltiazem Hcl [vandf]

    210. (+)-cis-diltiazem Hydrochlorid

    211. Diltiazem For System Suitability

    212. Dtxsid8040147

    213. Amy8835

    214. Slv-324

    215. Ven-307

    216. Hms1568k10

    217. (2s-trans)-diltiazem Hydrochloride

    218. Act02682

    219. Bcp13814

    220. Diltiazem Hydrochloride [mi]

    221. Tox21_500327

    222. Bnp-32762

    223. Diltiazem Hydrochloride (jp17/usp)

    224. Diltiazem Hydrochloride [jan]

    225. S1865

    226. 3,3,3-phosphinylidynetrispropionamide

    227. Diltiazem Hydrochloride [usan]

    228. Akos015961992

    229. Ccg-220134

    230. Ccg-221631

    231. Diltiazem Hydrochloride [mart.]

    232. Diltiazem Hydrochloride [vandf]

    233. Ks-5089

    234. Lp00327

    235. Nc00558

    236. Nsc 759576

    237. Diltiazem Hydrochloride [usp-rs]

    238. Diltiazem Hydrochloride [who-dd]

    239. Tetrahydrobenzo[b][1,4]thiazepin-3-yl

    240. Ncgc00093768-01

    241. Ncgc00261012-01

    242. (2s,3s)-(+)-3-acetoxy-2,3-dihydro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5h)-one Hydrochloride

    243. 1,5-benzothiazepin-4(5h)-one, 2,3-dihydro-3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-, Monohydrochloride, Cis-(+)-

    244. Ac-15189

    245. Ac-32469

    246. As-13703

    247. Bd166408

    248. Cis-(1)-3-acetoxy-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5h)-one Monohydrochloride

    249. Hy-14656

    250. (+)-cis-diltiazem Hydrochloride, >/=98%

    251. (2s,3s)-5-(2-(dimethylamino)ethyl)-2

    252. D3662

    253. Diltiazem Hydrochloride [ep Impurity]

    254. Diltiazem Hydrochloride [orange Book]

    255. Eu-0100327

    256. Sw196487-3

    257. Diltiazem Hydrochloride [ep Monograph]

    258. Bim-0050315.0001

    259. D 2521

    260. D00616

    261. Diltiazem Hydrochloride [usp Monograph]

    262. Diltiazem, Hydrochloride - Cas 33286-22-5

    263. F20448

    264. M01693

    265. (+)-cis-diltiazem Hydrochloride, >=99% (hplc)

    266. 286d225

    267. Sr-01000075327

    268. J-019130

    269. Sr-01000003042-2

    270. Sr-01000003042-4

    271. Sr-01000075327-1

    272. Q27105183

    273. Diltiazem Hydrochloride 1.0 Mg/ml In Acetonitrile (as Free Base)

    274. Diltiazem Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    275. Diltiazem Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    276. Diltiazem For System Suitability, European Pharmacopoeia (ep) Reference Standard

    277. (2s,3s)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl Acetate Hcl

    278. (2s,3s)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-ylacetatehydrochloride

    279. (2s-cis)-3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5h)-one Hydrochloride

    280. 1,5-benzothiazepin-4(5h)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, Hydrochloride (1:1), (2s,3s)-

    281. Acetic Acid (2s,3s)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl Ester; Hydrochloride

    282. Cis-(+)-3-acetoxy-2,3-dihydro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5h)-one Hydrochloride

    283. Diltiazem Hydrochloride Solution, 1.0 Mg/ml In Acetonitrile (as Free Base), Ampule Of 1 Ml, Certified Reference Material

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 451.0 g/mol
    Molecular Formula C22H27ClN2O4S
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count7
    Exact Mass450.1380062 g/mol
    Monoisotopic Mass450.1380062 g/mol
    Topological Polar Surface Area84.4 Ų
    Heavy Atom Count30
    Formal Charge0
    Complexity565
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 16  
    Drug NameCardizem
    PubMed HealthDiltiazem
    Drug ClassesAntianginal, Antihypertensive, Benzothiazepine, Calcium Channel Blocker, Cardiovascular Agent
    Drug LabelCARDIZEM (diltiazem hydrochloride) is a calcium ion cellular influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-...
    Active IngredientDiltiazem hydrochloride
    Dosage FormTablet
    RouteOral
    Strength60mg; 30mg; 90mg; 120mg
    Market StatusPrescription
    CompanyValeant Intl

    2 of 16  
    Drug NameCardizem cd
    Drug LabelCARDIZEM (diltiazem hydrochloride) is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2, 3-dihydro-2-(4-metho...
    Active IngredientDiltiazem hydrochloride
    Dosage FormCapsule, extended release
    RouteOral
    Strength300mg; 180mg; 120mg; 360mg; 240mg
    Market StatusPrescription
    CompanyValeant Intl

    3 of 16  
    Drug NameCardizem la
    PubMed HealthDiltiazem
    Drug ClassesAntianginal, Antihypertensive, Benzothiazepine, Calcium Channel Blocker, Cardiovascular Agent
    Drug LabelCARDIZEM LA (diltiazem hydrochloride) is a calcium ion cellular influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro...
    Active IngredientDiltiazem hydrochloride
    Dosage FormTablet, extended release
    RouteOral
    Strength300mg; 180mg; 420mg; 120mg; 360mg; 240mg
    Market StatusPrescription
    CompanyValeant Intl

    4 of 16  
    Drug NameCartia xt
    PubMed HealthDiltiazem (Intravenous route)
    Drug ClassesBenzothiazepine, Calcium Channel Blocker, Cardiovascular Agent
    Drug LabelDiltiazem hydrochloride is a calcium ion cellular influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-benzothiazepin-4(5H)one,3-(acetyloxy)-5-[2-(dimethylamino) ethyl]-2,3-dihydro-2-(4-methoxyphen...
    Active IngredientDiltiazem hydrochloride
    Dosage FormCapsule, extended release
    RouteOral
    Strength300mg; 180mg; 120mg; 240mg
    Market StatusPrescription
    CompanyActavis Labs Fl

    5 of 16  
    Drug NameDilacor xr
    Drug LabelDILACOR XR (diltiazem hydrochloride, USP) is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H)one,3-(acetyloxy)-5-[2-(dimethylamino) ethyl]-2,3-dihydro-2-(4-...
    Active IngredientDiltiazem hydrochloride
    Dosage FormCapsule, extended release
    RouteOral
    Strength180mg; 120mg; 240mg
    Market StatusPrescription
    CompanyWatson Labs

    6 of 16  
    Drug NameDiltiazem hydrochloride
    Drug LabelDiltiazem is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H)one,3-(acetyloxy)-5-[2-(dimethylamino) ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride...
    Active IngredientDiltiazem hydrochloride
    Dosage FormTablet, extended release; Injectable; Tablet; Capsule, extended release
    Routeinjection; Injection; Oral
    Strength300mg; 50mg/10ml; 180mg; 100mg/vial; 5mg/ml; 30mg; 60mg; 90mg; 125mg/25ml; 420mg; 120mg; 10mg/ml; 360mg; 240mg
    Market StatusPrescription
    CompanyIntl Medication; Bedford; Valeant Intl; Hospira; Hikma Maple; Actavis Labs Fl; Teva; Apotex; Hikma Farmaceutica; Teva Pharms Usa; Sandoz; Sun Pharma Global; Par Pharm; Mylan; Actavis; Akorn

    7 of 16  
    Drug NameTaztia xt
    Drug LabelTAZTIA XT brand ofDILTIAZEM HYDROCHLORIDE EXTENDED-RELEASECAPSULES USP(ONCE-A-DAY DOSAGE)Rx Only...
    Active IngredientDiltiazem hydrochloride
    Dosage FormCapsule, extended release
    RouteOral
    Strength180mg; 120mg; 360mg; 300mg; 240mg
    Market StatusPrescription
    CompanyActavis Labs Fl

    8 of 16  
    Drug NameTiazac
    Drug LabelTiazac (diltiazem hydrochloride) is a calcium ion cellular influx inhibitor (slow channel blocker). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2, 3-dihydro-2-(4-methoxyphenyl)-, mon...
    Active IngredientDiltiazem hydrochloride
    Dosage FormCapsule, extended release
    RouteOral
    Strength180mg; 420mg; 120mg; 360mg; 300mg; 240mg
    Market StatusPrescription
    CompanyValeant Intl

    9 of 16  
    Drug NameCardizem
    PubMed HealthDiltiazem
    Drug ClassesAntianginal, Antihypertensive, Benzothiazepine, Calcium Channel Blocker, Cardiovascular Agent
    Drug LabelCARDIZEM (diltiazem hydrochloride) is a calcium ion cellular influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-...
    Active IngredientDiltiazem hydrochloride
    Dosage FormTablet
    RouteOral
    Strength60mg; 30mg; 90mg; 120mg
    Market StatusPrescription
    CompanyValeant Intl

    10 of 16  
    Drug NameCardizem cd
    Drug LabelCARDIZEM (diltiazem hydrochloride) is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2, 3-dihydro-2-(4-metho...
    Active IngredientDiltiazem hydrochloride
    Dosage FormCapsule, extended release
    RouteOral
    Strength300mg; 180mg; 120mg; 360mg; 240mg
    Market StatusPrescription
    CompanyValeant Intl

    11 of 16  
    Drug NameCardizem la
    PubMed HealthDiltiazem
    Drug ClassesAntianginal, Antihypertensive, Benzothiazepine, Calcium Channel Blocker, Cardiovascular Agent
    Drug LabelCARDIZEM LA (diltiazem hydrochloride) is a calcium ion cellular influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro...
    Active IngredientDiltiazem hydrochloride
    Dosage FormTablet, extended release
    RouteOral
    Strength300mg; 180mg; 420mg; 120mg; 360mg; 240mg
    Market StatusPrescription
    CompanyValeant Intl

    12 of 16  
    Drug NameCartia xt
    PubMed HealthDiltiazem (Intravenous route)
    Drug ClassesBenzothiazepine, Calcium Channel Blocker, Cardiovascular Agent
    Drug LabelDiltiazem hydrochloride is a calcium ion cellular influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-benzothiazepin-4(5H)one,3-(acetyloxy)-5-[2-(dimethylamino) ethyl]-2,3-dihydro-2-(4-methoxyphen...
    Active IngredientDiltiazem hydrochloride
    Dosage FormCapsule, extended release
    RouteOral
    Strength300mg; 180mg; 120mg; 240mg
    Market StatusPrescription
    CompanyActavis Labs Fl

    13 of 16  
    Drug NameDilacor xr
    Drug LabelDILACOR XR (diltiazem hydrochloride, USP) is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H)one,3-(acetyloxy)-5-[2-(dimethylamino) ethyl]-2,3-dihydro-2-(4-...
    Active IngredientDiltiazem hydrochloride
    Dosage FormCapsule, extended release
    RouteOral
    Strength180mg; 120mg; 240mg
    Market StatusPrescription
    CompanyWatson Labs

    14 of 16  
    Drug NameDiltiazem hydrochloride
    Drug LabelDiltiazem is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H)one,3-(acetyloxy)-5-[2-(dimethylamino) ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride...
    Active IngredientDiltiazem hydrochloride
    Dosage FormTablet, extended release; Injectable; Tablet; Capsule, extended release
    Routeinjection; Injection; Oral
    Strength300mg; 50mg/10ml; 180mg; 100mg/vial; 5mg/ml; 30mg; 60mg; 90mg; 125mg/25ml; 420mg; 120mg; 10mg/ml; 360mg; 240mg
    Market StatusPrescription
    CompanyIntl Medication; Bedford; Valeant Intl; Hospira; Hikma Maple; Actavis Labs Fl; Teva; Apotex; Hikma Farmaceutica; Teva Pharms Usa; Sandoz; Sun Pharma Global; Par Pharm; Mylan; Actavis; Akorn

    15 of 16  
    Drug NameTaztia xt
    Drug LabelTAZTIA XT brand ofDILTIAZEM HYDROCHLORIDE EXTENDED-RELEASECAPSULES USP(ONCE-A-DAY DOSAGE)Rx Only...
    Active IngredientDiltiazem hydrochloride
    Dosage FormCapsule, extended release
    RouteOral
    Strength180mg; 120mg; 360mg; 300mg; 240mg
    Market StatusPrescription
    CompanyActavis Labs Fl

    16 of 16  
    Drug NameTiazac
    Drug LabelTiazac (diltiazem hydrochloride) is a calcium ion cellular influx inhibitor (slow channel blocker). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2, 3-dihydro-2-(4-methoxyphenyl)-, mon...
    Active IngredientDiltiazem hydrochloride
    Dosage FormCapsule, extended release
    RouteOral
    Strength180mg; 420mg; 120mg; 360mg; 300mg; 240mg
    Market StatusPrescription
    CompanyValeant Intl

    4.2 Drug Indication

    Treatment of chronic anal fissure

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Antihypertensive Agents

    Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)

    Vasodilator Agents

    Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)

    Calcium Channel Blockers

    A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)

    Cardiovascular Agents

    Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume. (See all compounds classified as Cardiovascular Agents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Calcium Channel Blocker [EPC]; Calcium Channel Antagonists [MoA]

    API Reference Price

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SOLA BRIDGE,, S.G. HIGHWAY, THALTEJ","city":"AHMEDABAD,GUJARAT","supplier":"FIS FABBRICA ITALIANA SINTETICI S P A","supplierCountry":"ITALY","foreign_port":"NA","customer":"INTAS PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"243.10","actualQuantity":"243.1","unit":"KGS","unitRateFc":"98","totalValueFC":"27174.8","currency":"EURO","unitRateINR":"9187.2","date":"31-Jul-2023","totalValueINR":"2233481.25","totalValueInUsd":"27174.8","indian_port":"AHMEDABAD AIR","hs_no":"29349990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"CORPORATE HOUSE, NR. SOLA BRIDGE,, S.G. HIGHWAY, THALTEJ"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1700850600,"product":"DILTIAZEM HYDROCHLORIDE (DILTIAZEM HYDROCHLORIDE EP\/BP\/IP\/USP\/PH.EUR.)","address":"2ND FLOOR, CHINUBHAI CENTRE,","city":"AHMEDABAD, GUJARAT","supplier":"FIS FABBRICA ITALIANA SINTETICI S P A","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"INTAS PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"4.50","actualQuantity":"4.5","unit":"KGS","unitRateFc":"98","totalValueFC":"485.9","currency":"EURO","unitRateINR":"8991.5","date":"25-Nov-2023","totalValueINR":"40461.75","totalValueInUsd":"485.9","indian_port":"Ahmedabad Air","hs_no":"29349990","bill_no":"8944617","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"VIALE MILANO,26 36705 MONTECCHIO MAGGIORE ITALY, , ItalySDNF Italy","customerAddress":"2ND FLOOR, CHINUBHAI CENTRE,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1700850600,"product":"DILTIAZEM HYDROCHLORIDE (DILTIAZEM HYDROCHLORIDE EP\/BP\/IP\/USP\/PH.EUR.)","address":"2ND FLOOR, CHINUBHAI CENTRE,","city":"AHMEDABAD, GUJARAT","supplier":"FIS FABBRICA ITALIANA SINTETICI S P A","supplierCountry":"ITALY","foreign_port":"MILAN - 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MALPENSA","supplierAddress":"VIALE MILANO,26 36705 MONTECCHIO MAGGIORE ITALY, , ItalySDNF Italy","customerAddress":"2ND FLOOR, CHINUBHAI CENTRE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1708626600,"product":"DILTIAZEM HYDROCHLORIDE API","address":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM","city":"","supplier":"XXODUXX","supplierCountry":"UNITED STATES","foreign_port":"LOS ANGELES","customer":"MS PAR FORMULATIONS PVT LTD","customerCountry":"INDIA","quantity":"1654.00","actualQuantity":"1654","unit":"KGS","unitRateFc":"80","totalValueFC":"133768.9","currency":"USD","unitRateINR":"6710.6","date":"23-Feb-2024","totalValueINR":"11099310","totalValueInUsd":"133768.9","indian_port":"Indore-EPZ\/SEZ","hs_no":"29349990","bill_no":"1001243","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"LOS ANGELES","supplierAddress":"N\/A","customerAddress":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1708626600,"product":"DILTIAZEM HYDROCHLORIDE API","address":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM","city":"","supplier":"XXODUXX","supplierCountry":"UNITED STATES","foreign_port":"LOS ANGELES","customer":"MS PAR FORMULATIONS PVT LTD","customerCountry":"INDIA","quantity":"2027.00","actualQuantity":"2027","unit":"KGS","unitRateFc":"80","totalValueFC":"163979.7","currency":"USD","unitRateINR":"6712.4","date":"23-Feb-2024","totalValueINR":"13606012","totalValueInUsd":"163979.7","indian_port":"Indore-EPZ\/SEZ","hs_no":"29349990","bill_no":"1001243","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"LOS ANGELES","supplierAddress":"N\/A","customerAddress":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717007400,"product":"DILTIAZEM HYDROCHLORIDE","address":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM","city":"","supplier":"FIS FABBRICA ITALIANA SINTETICI S P A","supplierCountry":"ITALY","foreign_port":"N\/A","customer":"MS PAR FORMULATIONS PVT LTD","customerCountry":"INDIA","quantity":"2064.00","actualQuantity":"2064","unit":"KGS","unitRateFc":"95","totalValueFC":"198451.4","currency":"USD","unitRateINR":"8014.4","date":"30-May-2024","totalValueINR":"16541752","totalValueInUsd":"198451.4","indian_port":"Indore-EPZ\/SEZ","hs_no":"29349990","bill_no":"1003860","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"N\/A","customerAddress":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718649000,"product":"DILTIAZEM HYDROCHLORIDE","address":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM","city":"","supplier":"FIS FABBRICA ITALIANA SINTETICI S P A","supplierCountry":"ITALY","foreign_port":"N\/A","customer":"MS PAR FORMULATIONS PVT LTD","customerCountry":"INDIA","quantity":"3153.00","actualQuantity":"3153","unit":"KGS","unitRateFc":"95","totalValueFC":"302465.9","currency":"USD","unitRateINR":"8008.1","date":"18-Jun-2024","totalValueINR":"25249679","totalValueInUsd":"302465.9","indian_port":"Indore-EPZ\/SEZ","hs_no":"29349990","bill_no":"1004333","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"VIALE MILANO, 26-36075 MONTECCHIO M AGGIO RE (VI) - ITALY , , Italy Italy","customerAddress":"OLD NO.1\/63, NEW NO.1\/58 PUDUPAKKAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1721586600,"product":"DILTIAZEM HYDROCHLORIDE USP LOT NO-2038406","address":"1\/5, SANTOSH COMPLEX, ARMUGAM","city":"BANGALORE , KARNATAKA","supplier":"SAGENT PHARMACEUTICALS INC","supplierCountry":"UNITED STATES","foreign_port":"NEW YORK - JOHN F. 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BOX 28 FI-02101 ESPOO FI","customerAddress":"1\/5, SANTOSH COMPLEX, ARMUGAM"}]
    21-Jan-2022
    26-Apr-2025
    KGS
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    DOSAGE - TABLET;ORAL - 120MG

    USFDA APPLICATION NUMBER - 18602

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    DOSAGE - TABLET;ORAL - 30MG

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    DOSAGE - TABLET;ORAL - 60MG

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    DOSAGE - TABLET;ORAL - 90MG

    USFDA APPLICATION NUMBER - 18602

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 120...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 120MG

    USFDA APPLICATION NUMBER - 20062

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 180...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 180MG

    USFDA APPLICATION NUMBER - 20062

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 240...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 240MG

    USFDA APPLICATION NUMBER - 20062

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 300...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 300MG

    USFDA APPLICATION NUMBER - 20062

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 360...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 360MG

    USFDA APPLICATION NUMBER - 20062

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 120...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 120MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 20092

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 180...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 180MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 20092

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 240...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 240MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 20092

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 120...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 120MG

    USFDA APPLICATION NUMBER - 20401

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 180...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 180MG

    USFDA APPLICATION NUMBER - 20401

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 240...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 240MG

    USFDA APPLICATION NUMBER - 20401

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 300...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 300MG

    USFDA APPLICATION NUMBER - 20401

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 360...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 360MG

    USFDA APPLICATION NUMBER - 20401

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    DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 420...DOSAGE - CAPSULE, EXTENDED RELEASE;ORAL - 420MG

    USFDA APPLICATION NUMBER - 20401

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 120M...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 120MG

    USFDA APPLICATION NUMBER - 21392

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 180M...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 180MG

    USFDA APPLICATION NUMBER - 21392

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 240M...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 240MG

    USFDA APPLICATION NUMBER - 21392

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 300M...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 300MG

    USFDA APPLICATION NUMBER - 21392

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 360M...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 360MG

    USFDA APPLICATION NUMBER - 21392

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    DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 420M...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 420MG

    USFDA APPLICATION NUMBER - 21392

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    Diltiazem Hydrochloride manufacturers, exporters & distributors 1

    18

    PharmaCompass offers a list of Diltiazem Hydrochloride API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Diltiazem Hydrochloride manufacturer or Diltiazem Hydrochloride supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Diltiazem Hydrochloride manufacturer or Diltiazem Hydrochloride supplier.

    PharmaCompass also assists you with knowing the Diltiazem Hydrochloride API Price utilized in the formulation of products. Diltiazem Hydrochloride API Price is not always fixed or binding as the Diltiazem Hydrochloride Price is obtained through a variety of data sources. The Diltiazem Hydrochloride Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Diltiazem Hydrochloride

    Synonyms

    33286-22-5, Diltiazem hcl, Cardizem, Dilzem, Dilzene, Masdil

    Cas Number

    33286-22-5

    Unique Ingredient Identifier (UNII)

    OLH94387TE

    About Diltiazem Hydrochloride

    A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.

    Watson Pharmaceuticals Brand of Diltazem Manufacturers

    A Watson Pharmaceuticals Brand of Diltazem manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Watson Pharmaceuticals Brand of Diltazem, including repackagers and relabelers. The FDA regulates Watson Pharmaceuticals Brand of Diltazem manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Watson Pharmaceuticals Brand of Diltazem API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Watson Pharmaceuticals Brand of Diltazem manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Watson Pharmaceuticals Brand of Diltazem Suppliers

    A Watson Pharmaceuticals Brand of Diltazem supplier is an individual or a company that provides Watson Pharmaceuticals Brand of Diltazem active pharmaceutical ingredient (API) or Watson Pharmaceuticals Brand of Diltazem finished formulations upon request. The Watson Pharmaceuticals Brand of Diltazem suppliers may include Watson Pharmaceuticals Brand of Diltazem API manufacturers, exporters, distributors and traders.

    click here to find a list of Watson Pharmaceuticals Brand of Diltazem suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Watson Pharmaceuticals Brand of Diltazem USDMF

    A Watson Pharmaceuticals Brand of Diltazem DMF (Drug Master File) is a document detailing the whole manufacturing process of Watson Pharmaceuticals Brand of Diltazem active pharmaceutical ingredient (API) in detail. Different forms of Watson Pharmaceuticals Brand of Diltazem DMFs exist exist since differing nations have different regulations, such as Watson Pharmaceuticals Brand of Diltazem USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Watson Pharmaceuticals Brand of Diltazem DMF submitted to regulatory agencies in the US is known as a USDMF. Watson Pharmaceuticals Brand of Diltazem USDMF includes data on Watson Pharmaceuticals Brand of Diltazem's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Watson Pharmaceuticals Brand of Diltazem USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Watson Pharmaceuticals Brand of Diltazem suppliers with USDMF on PharmaCompass.

    Watson Pharmaceuticals Brand of Diltazem JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Watson Pharmaceuticals Brand of Diltazem Drug Master File in Japan (Watson Pharmaceuticals Brand of Diltazem JDMF) empowers Watson Pharmaceuticals Brand of Diltazem API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Watson Pharmaceuticals Brand of Diltazem JDMF during the approval evaluation for pharmaceutical products. At the time of Watson Pharmaceuticals Brand of Diltazem JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Watson Pharmaceuticals Brand of Diltazem suppliers with JDMF on PharmaCompass.

    Watson Pharmaceuticals Brand of Diltazem KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Watson Pharmaceuticals Brand of Diltazem Drug Master File in Korea (Watson Pharmaceuticals Brand of Diltazem KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Watson Pharmaceuticals Brand of Diltazem. The MFDS reviews the Watson Pharmaceuticals Brand of Diltazem KDMF as part of the drug registration process and uses the information provided in the Watson Pharmaceuticals Brand of Diltazem KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Watson Pharmaceuticals Brand of Diltazem KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Watson Pharmaceuticals Brand of Diltazem API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Watson Pharmaceuticals Brand of Diltazem suppliers with KDMF on PharmaCompass.

    Watson Pharmaceuticals Brand of Diltazem CEP

    A Watson Pharmaceuticals Brand of Diltazem CEP of the European Pharmacopoeia monograph is often referred to as a Watson Pharmaceuticals Brand of Diltazem Certificate of Suitability (COS). The purpose of a Watson Pharmaceuticals Brand of Diltazem CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Watson Pharmaceuticals Brand of Diltazem EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Watson Pharmaceuticals Brand of Diltazem to their clients by showing that a Watson Pharmaceuticals Brand of Diltazem CEP has been issued for it. The manufacturer submits a Watson Pharmaceuticals Brand of Diltazem CEP (COS) as part of the market authorization procedure, and it takes on the role of a Watson Pharmaceuticals Brand of Diltazem CEP holder for the record. Additionally, the data presented in the Watson Pharmaceuticals Brand of Diltazem CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Watson Pharmaceuticals Brand of Diltazem DMF.

    A Watson Pharmaceuticals Brand of Diltazem CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Watson Pharmaceuticals Brand of Diltazem CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Watson Pharmaceuticals Brand of Diltazem suppliers with CEP (COS) on PharmaCompass.

    Watson Pharmaceuticals Brand of Diltazem WC

    A Watson Pharmaceuticals Brand of Diltazem written confirmation (Watson Pharmaceuticals Brand of Diltazem WC) is an official document issued by a regulatory agency to a Watson Pharmaceuticals Brand of Diltazem manufacturer, verifying that the manufacturing facility of a Watson Pharmaceuticals Brand of Diltazem active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Watson Pharmaceuticals Brand of Diltazem APIs or Watson Pharmaceuticals Brand of Diltazem finished pharmaceutical products to another nation, regulatory agencies frequently require a Watson Pharmaceuticals Brand of Diltazem WC (written confirmation) as part of the regulatory process.

    click here to find a list of Watson Pharmaceuticals Brand of Diltazem suppliers with Written Confirmation (WC) on PharmaCompass.

    Watson Pharmaceuticals Brand of Diltazem NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Watson Pharmaceuticals Brand of Diltazem as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Watson Pharmaceuticals Brand of Diltazem API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Watson Pharmaceuticals Brand of Diltazem as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Watson Pharmaceuticals Brand of Diltazem and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Watson Pharmaceuticals Brand of Diltazem NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Watson Pharmaceuticals Brand of Diltazem suppliers with NDC on PharmaCompass.

    Watson Pharmaceuticals Brand of Diltazem GMP

    Watson Pharmaceuticals Brand of Diltazem Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Watson Pharmaceuticals Brand of Diltazem GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Watson Pharmaceuticals Brand of Diltazem GMP manufacturer or Watson Pharmaceuticals Brand of Diltazem GMP API supplier for your needs.

    Watson Pharmaceuticals Brand of Diltazem CoA

    A Watson Pharmaceuticals Brand of Diltazem CoA (Certificate of Analysis) is a formal document that attests to Watson Pharmaceuticals Brand of Diltazem's compliance with Watson Pharmaceuticals Brand of Diltazem specifications and serves as a tool for batch-level quality control.

    Watson Pharmaceuticals Brand of Diltazem CoA mostly includes findings from lab analyses of a specific batch. For each Watson Pharmaceuticals Brand of Diltazem CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Watson Pharmaceuticals Brand of Diltazem may be tested according to a variety of international standards, such as European Pharmacopoeia (Watson Pharmaceuticals Brand of Diltazem EP), Watson Pharmaceuticals Brand of Diltazem JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Watson Pharmaceuticals Brand of Diltazem USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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