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Chemistry

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Also known as: Butanedioic acid, 110-15-6, Amber acid, Wormwood acid, Asuccin, Dihydrofumaric acid
Molecular Formula
C4H6O4
Molecular Weight
118.09  g/mol
InChI Key
KDYFGRWQOYBRFD-UHFFFAOYSA-N
FDA UNII
AB6MNQ6J6L

Succinic Acid
A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
1 2D Structure

Succinic Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
butanedioic acid
2.1.2 InChI
InChI=1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
2.1.3 InChI Key
KDYFGRWQOYBRFD-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C(CC(=O)O)C(=O)O
2.2 Other Identifiers
2.2.1 UNII
AB6MNQ6J6L
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1,2 Ethanedicarboxylic Acid

2. 1,2-ethanedicarboxylic Acid

3. 1,4 Butanedioic Acid

4. 1,4-butanedioic Acid

5. Ammonium Succinate

6. Butanedioic Acid

7. Succinate

8. Succinate, Ammonium

2.3.2 Depositor-Supplied Synonyms

1. Butanedioic Acid

2. 110-15-6

3. Amber Acid

4. Wormwood Acid

5. Asuccin

6. Dihydrofumaric Acid

7. Katasuccin

8. 1,2-ethanedicarboxylic Acid

9. Bernsteinsaure

10. Ethylenesuccinic Acid

11. 1,4-butanedioic Acid

12. Wormwood

13. Succinicum Acidum

14. Butandisaeure

15. Acidum Succinicum

16. Butanedionic Acid

17. Kyselina Jantarova

18. Butane Diacid

19. Ethylene Dicarboxylic Acid

20. Spirit Of Amber

21. Bernsteinsaure [german]

22. Kyselina Jantarova [czech]

23. Ammonium Succinate

24. Hsdb 791

25. Succinic-acid

26. Mfcd00002789

27. Succ

28. Nsc 106449

29. Ai3-06297

30. Ab6mnq6j6l

31. Nsc-106449

32. Butanedioic Acid, Homopolymer

33. E363

34. Fema No. 4719

35. Chebi:15741

36. C4-beta-polymorph

37. Nsc25949

38. Succinicacid(industrialgrade&foodgrade)

39. Ncgc00159372-02

40. Ncgc00159372-04

41. Succinellite

42. Acide Succinique

43. Sal Succini

44. Acid Of Amber

45. Dsstox_cid_3602

46. Wln: Qv2vq

47. Dsstox_rid_77102

48. Dsstox_gsid_23602

49. 26776-24-9

50. Sin

51. Ethylene Succinic Acid

52. Ethanedicarboxylic Acid

53. Bernsteinsaeure

54. Sodium Succinate (anhydrous)

55. Succinate, 9

56. Acide Butanedioique

57. Cas-110-15-6

58. Succinic Acid [nf]

59. Succinic Acid (8ci)

60. Butanedioic Acid (9ci)

61. Einecs 203-740-4

62. Unii-ab6mnq6j6l

63. Brn 1754069

64. Dihydrofumarate

65. Succinicate

66. Butanedioic Acid Diammonium Salt

67. Salt Of Amber

68. 1cze

69. Nat.succinic Acid

70. 1,4-butanedioate

71. Succinic Acid, 6

72. Succinic Acid, Fcc

73. Succinic Acide,(s)

74. Succinic Acid (sa)

75. 1,4-butandioic Acid

76. Succinic Acid, 99%

77. Succinic Acid, Natural

78. 4lh2

79. 1,2-ethanedicarboxylate

80. Substrate Analogue, 11

81. Suc

82. Succinic Acid, Acs Grade

83. Bmse000183

84. Bmse000968

85. Chembl576

86. Ec 203-740-4

87. Succinic Acid [ii]

88. Succinic Acid [mi]

89. Hooc-ch2-ch2-cooh

90. Succinic Acid [fcc]

91. A 12084

92. Succinic Acid [hsdb]

93. Succinic Acid [inci]

94. 4-02-00-01908 (beilstein Handbook Reference)

95. Succinic Acid [vandf]

96. Succinic Acid [mart.]

97. Gtpl3637

98. Succinic Acid [usp-rs]

99. Succinic Acid [who-dd]

100. Dtxsid6023602

101. Succinicum Acidum [hpus]

102. Bdbm26121

103. Succinic Acid (butanedioic Acid)

104. Hms3885o04

105. Zinc895030

106. Hy-n0420

107. Str02803

108. Tox21_111612

109. Tox21_201918

110. Tox21_303247

111. Bbl002473

112. Lmfa01170043

113. Nsc-25949

114. Nsc106449

115. S3791

116. Stk387105

117. Succinic Acid [usp Impurity]

118. Succinic Acid, >=99%, Fcc, Fg

119. Succinic Acid, Bioxtra, >=99.0%

120. Akos000118899

121. Tox21_111612_1

122. Ccg-266069

123. Db00139

124. Ncgc00159372-03

125. Ncgc00159372-05

126. Ncgc00159372-06

127. Ncgc00257092-01

128. Ncgc00259467-01

129. Succinic Acid, Acs Reagent, >=99.0%

130. Bp-21128

131. Succinic Acid, Reagentplus(r), >=99.0%

132. Adipic Acid Impurity B [ep Impurity]

133. Cs-0008946

134. Ft-0652509

135. Ft-0773657

136. N1941

137. S0100

138. Succinic Acid 100 Microg/ml In Acetonitrile

139. Succinic Acid, P.a., Acs Reagent, 99.0%

140. Succinic Acid, Saj First Grade, >=99.0%

141. Succinic Acid High Purity Grade 2.5kg

142. Succinic Acid, Purum P.a., >=99.0% (t)

143. Succinic Acid, Saj Special Grade, >=99.5%

144. 1,4-butanedioic Acid (succinic Acid)

145. A14596

146. C00042

147. D85169

148. Succinic Acid, Vetec(tm) Reagent Grade, 98%

149. Ab01332192-02

150. Q213050

151. Sr-01000944556

152. J-002386

153. Sr-01000944556-2

154. Z57127453

155. F2191-0239

156. 37e8fffb-70da-4399-b724-476bd8715ef0

157. Succinic Acid, Certified Reference Material, Tracecert(r)

158. Succinic Acid, Puriss. P.a., Acs Reagent, >=99.5% (t)

159. Succinic Acid, United States Pharmacopeia (usp) Reference Standard

160. Succinic Acid, Matrix Substance For Maldi-ms, >=99.5% (t), Ultra Pure

161. Succinic Acid, Anhydrous, Free-flowing, Redi-dri(tm), Acs Reagent, >=99.0%

162. Succinic Acid, Bioreagent, Suitable For Cell Culture, Suitable For Insect Cell Culture

163. Succinic Acid, Pharmaceutical Secondary Standard; Certified Reference Material

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 118.09 g/mol
Molecular Formula C4H6O4
XLogP3-0.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass118.02660867 g/mol
Monoisotopic Mass118.02660867 g/mol
Topological Polar Surface Area74.6 Ų
Heavy Atom Count8
Formal Charge0
Complexity92.6
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Therapeutic Uses

/EXPTL THER/ Succinic acid (100 mM) significantly inhibited systemic anaphylaxis induced by compound 48/80 /a potent mast cell degranulator/ in mice and dose-dependently inhibited local anaphylaxis activated by anti-dinitrophenyl IgE. Further 10 and 100 mM significantly inhibited histamine release from rat peritoneal mast cells activated by compound 48/80 or anti-dinitrophenyl IgE. In addition succinic acid (0.1 and 1 mM) had a significant inhibitory effect on anti-dinitrophenyl IgE-induced tumor necrosis factor-alpha secretion from rat peritoneal mast cells. The level of cyclic AMP in rat peritoneal mast cells, when succinic acid (100 mM) was added, transiently and significantly increased about 4 times compared with that of basal cells. These results suggest a possible use of succinic acid in managing mast cell-dependent anaphylaxis.

Kim HM et al;


4.2 Drug Indication

For nutritional supplementation, also for treating dietary shortage or imbalance


5 Pharmacology and Biochemistry
5.1 Absorption, Distribution and Excretion

Succinic acid occurs normally in human urine (1.9-8.8 mg/L).

Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V5 758


5.2 Metabolism/Metabolites

Succinic acid is a normal intermediary metabolite and a constituent of the citric acid cycle. It is readily metabolized when administered to animals, but may be partly excreted unchanged in the urine if large doses are fed.

Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V5 757


5.3 Mechanism of Action

Succinate is an essential component of the Krebs or citric acid cycle and serves an electron donor in the production of fumaric acid and FADH2. It also has been shown to be a good "natural" antibiotic because of its relative acidic or caustic nature (high concentrations can even cause burns). Succinate supplements have been shown to help reduce the effects of hangovers by activating the degradation of acetaldehyde - a toxic byproduct of alcohol metabolism - into CO2 and H2O through aerobic metabolism. Succinic acid has been shown to stimulate neural system recovery and bolster the immune system. Claims have also been made that it boosts awareness, concentration and reflexes.


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MOORESTOWN NJ 08057 SDNF SDNF US","customerAddress":"1-5 SEVEN WELLS STREET"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1745605800,"product":"SUCCINIC ACID CRYST., EMPROVE ESSENTIAL CHP,NF,JPE,ACS 6PCSX 5KG (PHARMA GRADE)ORGANIC CHEMICAL","address":"50A , RING ROAD,","city":"BANGALORE, KARNATAKA","supplier":"MERCK LIFE SCIENCE KGAA","supplierCountry":"AUSTRIA","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"MERCK LIFE SCIENCE PRIVATE LTD","customerCountry":"INDIA","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"72","totalValueFC":"2180.6","currency":"USD","unitRateINR":"6222.1","date":"26-Apr-2025","totalValueINR":"186661.97","totalValueInUsd":"2180.6","indian_port":"Bombay Air","hs_no":"29171930","bill_no":"9720669","productDescription":"API","marketType":"REGULATED MARKET","country":"AUSTRIA","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"Frankfurter Strasse 25064293 Darmst adt Germany (BENEFICIARY MERCKFINA NCIAL SERVICES GMBH) GERMANY","customerAddress":"50A , RING ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1746556200,"product":"SUCCINIC ACID CRYST., EMPROVE ESSENTIAL CHP,NF,JPE,ACS 6PCSX 5KG (PHARMA GRADE)ORGANIC CHEMICAL","address":"50A , RING ROAD,","city":"BANGALORE, KARNATAKA","supplier":"MERCK LIFE SCIENCE KGAA","supplierCountry":"AUSTRIA","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"MERCK LIFE SCIENCE PRIVATE LTD","customerCountry":"INDIA","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"72.7","totalValueFC":"2190.9","currency":"N\/A","unitRateINR":"6222.1","date":"07-May-2025","totalValueINR":"186661.97","totalValueInUsd":"2190.9","indian_port":"Bombay Air","hs_no":"29171930","bill_no":"9921256","productDescription":"API","marketType":"REGULATED MARKET","country":"AUSTRIA","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"Frankfurter Strasse 25064293 Darmst adt Germany (BENEFICIARY MERCKFINA NCIAL SERVICES GMBH) GERMANY","customerAddress":"50A , RING ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1747765800,"product":"(2S,3S)-2,3-BIS(PIVALOYLOXY)SUCCINIC ACID","address":"BIOCON SEZ, BIOCON PARK,PLOT NO.2 3","city":"N\/A","supplier":"BLD PHARMATECH LTD","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"SYNGENE INTERNATIONAL LTD UNIT X","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1000","unit":"GMS","unitRateFc":"0.6","totalValueFC":"557.7","currency":"USD","unitRateINR":"47.5","date":"21-May-2025","totalValueINR":"47520","totalValueInUsd":"557.7","indian_port":"Biocon-SEZ","hs_no":"29420090","bill_no":"1004771","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"488 TAOQIAO ROAD, BUILDING 5, 5F HU INAN TOWN PUDONG NEW AREA SHANGHAI Pudong\/Shanghai, Shanghai, China China","customerAddress":"BIOCON SEZ, BIOCON PARK,PLOT NO.2 3"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1748370600,"product":"SUCCINIC ACID FOR SYNTHESIS 2PCS X 250GMS ORGANIC CHEMICALS","address":"50A , RING ROAD,","city":"BANGALORE, KARNATAKA","supplier":"MERCK LIFE SCIENCE KGAA","supplierCountry":"AUSTRIA","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"MERCK LIFE SCIENCE PRIVATE LTD","customerCountry":"INDIA","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"57.4","totalValueFC":"29.1","currency":"N\/A","unitRateINR":"4961.6","date":"28-May-2025","totalValueINR":"2480.79","totalValueInUsd":"29.1","indian_port":"Bombay Air","hs_no":"29171930","bill_no":"2323140","productDescription":"API","marketType":"REGULATED MARKET","country":"AUSTRIA","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"Frankfurter Strasse 250, 64293 Darm stadt,(BENEFICIARY MERCKFINANCIALS SERVICES GMBH) GERMANY","customerAddress":"50A , RING ROAD,"}]
17-Jan-2022
28-May-2025
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ABOUT THIS PAGE

Looking for 110-15-6 / Succinic Acid API manufacturers, exporters & distributors?

Succinic Acid manufacturers, exporters & distributors 1

27

PharmaCompass offers a list of Succinic Acid API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Succinic Acid manufacturer or Succinic Acid supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Succinic Acid manufacturer or Succinic Acid supplier.

PharmaCompass also assists you with knowing the Succinic Acid API Price utilized in the formulation of products. Succinic Acid API Price is not always fixed or binding as the Succinic Acid Price is obtained through a variety of data sources. The Succinic Acid Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Succinic Acid

Synonyms

Butanedioic acid, 110-15-6, Amber acid, Wormwood acid, Asuccin, Dihydrofumaric acid

Cas Number

110-15-6

Unique Ingredient Identifier (UNII)

AB6MNQ6J6L

About Succinic Acid

A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)

Succinic Acid Manufacturers

A Succinic Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Succinic Acid, including repackagers and relabelers. The FDA regulates Succinic Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Succinic Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Succinic Acid manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Succinic Acid Suppliers

A Succinic Acid supplier is an individual or a company that provides Succinic Acid active pharmaceutical ingredient (API) or Succinic Acid finished formulations upon request. The Succinic Acid suppliers may include Succinic Acid API manufacturers, exporters, distributors and traders.

click here to find a list of Succinic Acid suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Succinic Acid GMP

Succinic Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Succinic Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Succinic Acid GMP manufacturer or Succinic Acid GMP API supplier for your needs.

Succinic Acid CoA

A Succinic Acid CoA (Certificate of Analysis) is a formal document that attests to Succinic Acid's compliance with Succinic Acid specifications and serves as a tool for batch-level quality control.

Succinic Acid CoA mostly includes findings from lab analyses of a specific batch. For each Succinic Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Succinic Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (Succinic Acid EP), Succinic Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Succinic Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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