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Details:

VS-6766 (avutometinib) in combination with Lumakras (sotorasib) is being evaluated in phase 1/2 clinical studies for the treatment of KRAS G12C-Mutant Non-Small Cell Lung Cancer (NSCLC).


Lead Product(s): VS-6766,Sotorasib

Therapeutic Area: Oncology Product Name: VS-6766

Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 18, 2024

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Lumakras (sotorasib) is a small molecule, KRAS G12C inhibitor. It is approved for the treatment of adult patients with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC).


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 26, 2023

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Lumakras (Sotorasib) was the first KRASG12C inhibitor to receive regulatory approval with its approval in the U.S., under accelerated approval for the treatment of metastatic KRAS G12C-mutated non-small cell lung cancer.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 21, 2023

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Details:

VIC-1911 is a novel, highly selective, and orally active small molecular inhibitor of aurora kinase A (AURKA). AURKA gene amplification/overexpression is reported in multiple tumors, including NSCLC.


Lead Product(s): VIC-1911,Sotorasib

Therapeutic Area: Oncology Product Name: VIC-1911

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 24, 2023

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Details:

SHP2 (PTPN11), a cellular enzyme in the protein tyrosine phosphatase family, plays an important role in multiple forms of cancer and in regulating the immune system.


Lead Product(s): Vociprotafib,Sotorasib

Therapeutic Area: Oncology Product Name: RMC-4630

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Sanofi

Deal Size: $550.0 million Upfront Cash: $50.0 million

Deal Type: Termination December 07, 2022

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ABI-009 (Nab-sirolimus) is a novel albumin-bound nanoparticle form of the mTOR inhibitor sirolimus and is approved for the treatment of locally advanced unresectable or metastatic malignant perivascular epithelioid cell tumor (PEComa).


Lead Product(s): Nab-sirolimus,Sotorasib,Adagrasib

Therapeutic Area: Oncology Product Name: ABI-009

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 27, 2022

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BBP-398 is a SHP2 inhibitor and as a monotherapy or in combination with other targeted therapies, could potentially be a promising therapy for patients with the KRAS G12C mutation.


Lead Product(s): BBP-398,Sotorasib

Therapeutic Area: Oncology Product Name: BBP-398

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 11, 2022

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Data showed that combining LUMAKRAS®/LUMYKRAS® (sotorasib) with Vectibix® (panitumumab), Amgen's monoclonal anti-epidermal growth factor receptor (anti-EGFR) antibody, demonstrated encouraging efficacy and safety.


Lead Product(s): Sotorasib,Panitumumab

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 12, 2022

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LUMAKRAS (sotorasib) significantly improved PFS as determined by Blinded Independent Central Review (BICR) compared to docetaxel in heavily pre-treated patients (median PFS of 5.6 vs 4.5 months, respectively; HR, 0.66 [95% CI: 0.51, 0.86]; P = 0.002).


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 11, 2022

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LUMAKRAS/LUMYKRAS (sotorasib) has demonstrated a positive benefit-risk profile with rapid, deep, and durable anticancer activity in patients with locally advanced or metastatic non-small cell lung cancer harboring the KRAS G12C mutation with a once daily oral formulation.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 30, 2022

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Details:

ERAS-007 is a potential best-in-class ERK1/2 inhibitor being investigated alone or in combination with different inhibitors targeting upstream nodes of the MAPK pathway as part of Erasca’s MAPKlamp strategy.


Lead Product(s): ERAS-007,Sotorasib

Therapeutic Area: Oncology Product Name: ERAS-007

Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 02, 2022

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Details:

LUMAKRAS/LUMYKRAS (sotorasib) has demonstrated a positive benefit-risk profile with rapid, deep, and durable anticancer activity in patients with locally advanced or NSCLC harboring the KRAS G12C mutation with a once daily oral formulation.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 27, 2022

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Details:

In preclinical study, Immuneering researchers tested IMM-1-104 in a head-to-head comparison versus agent, in a series of preclinical models to characterize differential activity of each compound against pancreatic tumors driven by diverse KRAS mutations.


Lead Product(s): IMM-1-104,Sotorasib

Therapeutic Area: Oncology Product Name: IMM-1-104

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 26, 2022

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Details:

Lumakras (sotorasib) , a KRASG12C inhibitor demonstrated a centrally confirmed objective response rate (ORR) of 40.7%, disease control rate (DCR) of 83.7% and median duration of response (DOR) of 12.3 months.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 10, 2022

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Details:

LUMAKRAS/LUMYKRAS has demonstrated a positive benefit-risk profile with rapid, deep, and durable anticancer activity in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring the KRAS G12C mutation with a once daily oral formulation.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 08, 2022

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Details:

LUMAKRAS demonstrated a centrally confirmed objective response rate (ORR) of 21% and disease control rate (DCR) of 84% across 38 heavily pre-treated advanced pancreatic cancer patients. Nearly 80% of patients received LUMAKRAS as a third-line or later therapy.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 14, 2022

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LUMAKRAS (sotorasib) KRAS G12C Inhibitor, approval based on pivotal Codebreaker 100 data demonstrating durable responses and a favorable benefit-risk profile in the treatment of patients with non-small cell lung cancer.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 20, 2022

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Details:

First patient dosed in global phase 2 clinical trial evaluating the combination of RMC-4630 (SAR442720)and lumakras™ (sotorasib) in patients with advanced non-small-cell lung cancer.


Lead Product(s): Vociprotafib,Sotorasib

Therapeutic Area: Oncology Product Name: RMC-4630

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 11, 2022

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Details:

First Targeted Therapy for Patients With the KRAS G12C Mutation Approved in the European Union and the approval is based on Pivotal CodeBreaK 100 data demonstrating durable responses and a favorable benefit-risk profile with LUMYKRAS (Sotorasib).


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumykras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 09, 2022

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Details:

The Lancet Oncology study is a proof of principle that targeting KRAS G12C with a small molecule KRAS G12C inhibitor, sotorasib, can lead to tumor shrinkage and meaningful duration of disease control in a patient population that otherwise has very limited treatment options.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 14, 2021

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Details:

In the trial, LUMYKRAS demonstrated favorable efficacy and tolerability in these 124 patients with KRAS G12C mutation-positive NSCLC who had disease progression after receiving an immunotherapy and/or chemotherapy.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumykras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 12, 2021

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Details:

IMM-1-104 is designed to be a highly selective dual-MEK inhibitor that further disrupts the kinase suppressor of RAS 1 and 2 (KSR1/2) for the treatment of advanced solid tumors in patients harboring RAS mutant tumors.


Lead Product(s): IMM-1-104,Sotorasib

Therapeutic Area: Oncology Product Name: IMM-1-104

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 11, 2021

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Details:

IMM-1-104: a novel, oral, selective dual-MEK inhibitor that displays broad antitumor activity and high tolerability across RAS and RAF mutant tumors.


Lead Product(s): IMM-1-104,Sotorasib

Therapeutic Area: Oncology Product Name: IMM-1-104

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 01, 2021

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Details:

Verastem has signed collaboration agreement to explore the potential of VS-6766 as a therapy to treat RAS pathway-driven cancers and to evaluate the combination of VS-6766 with Amgen’s KRAS G12C inhibitor LUMAKRAS (sotorasib) in KRAS G12C-mutant non-small cell lung cancer.


Lead Product(s): VS-6766,Sotorasib

Therapeutic Area: Oncology Product Name: VS-6766

Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Amgen Inc

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration September 20, 2021

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Details:

New data support initiation of Phase 3 trial of LUMAKRAS plus Vectibix in patients with 3L+ KRAS G12C-mutated advanced colorectal cancer (CRC). 9.7% response rate observed with LUMAKRAS monotherapy and highlight the importance of combination therapy in CodeBreaK 101 data.


Lead Product(s): Sotorasib,Panitumumab

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 16, 2021

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Details:

New LUMAKRAS™ (sotorasib) Post-Hoc Analysis Shows Intracranial Disease Control was Achieved in a Subset of Patients With Previously Treated Evaluable Stable Brain Metastases.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 08, 2021

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Details:

Using the lung biopsy specimen, the assay identifies whether a patient with NSCLC has a specific mutation in the KRAS gene and is eligible for treatment with LUMAKRAS™ (sotorasib) which was developed by Amgen.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Amgen Inc

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 01, 2021

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Details:

FDA recently approved LUMAKRAS for the treatment of adult patients with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC), as determined by an FDA-approved test, who have received at least one prior systemic therapy.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Amgen Inc

Deal Size: $240.0 million Upfront Cash: Undisclosed

Deal Type: Collaboration June 29, 2021

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  • Development Update

Details:

Sotorasib is a novel covalent inhibitor that, thanks to recent advances in medical chemistry, can target a specific building block (cysteine residue) only present in the inactive form of KRAS.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Amgen Inc

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 04, 2021

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Details:

The FDA approval of LUMAKRAS is based on results from a subset of patients in CodeBreaK 100, the largest clinical trial conducted to date exclusively for patients with the KRAS G12C mutation.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 28, 2021

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Details:

QIAGEN’s therascreen KRAS Kit was used to support the CodeBreaK 100 clinical trial of sotorasib and the expansion of the Kit’s CDx claims to include identification of the KRAS G12C mutation in NSCLC samples has been co-approved with LUMAKRAS by the FDA.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 28, 2021

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Details:

The FDA approval of LUMAKRAS is based on results from a subset of patients in CodeBreaK 100, the largest clinical trial conducted to date exclusively for patients with the KRAS G12C mutation.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Lumakras

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 28, 2021

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Details:

The U.S. Food and Drug Administration (FDA) has granted Priority Review for Amgen's sotorasib for the treatment of patients with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC), following at least one prior systemic therapy.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: AMG 510

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 16, 2021

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Details:

The Breakthrough Therapy Designation is supported by the positive CodeBreaK 100 Phase 2 results. In the study, treatment with sotorasib demonstrated durable anticancer activity with a positive benefit-risk profile.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: AMG510

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 29, 2021

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Details:

Sotorasib demonstrated a confirmed objective response rate (ORR) and disease control rate (DCR) of 37.1% and 80.6%, respectively, and a median duration of response of 10 months (data cutoff of Dec.1, 2020; median follow-up time was 12.2 months).


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: AMG510

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 28, 2021

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Details:

The submission is supported by positive Phase 2 results in which treatment with sotorasib provided durable anticancer activity with a positive benefit-risk profile.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: AMG 510

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 16, 2020

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Details:

The designation and RTOR are supported by positive Phase 2 results in patients with advanced NSCLC from the CodeBreaK 100 clinical study. In the study, treatment with sotorasib provided durable anticancer activity with a positive benefit-risk profile.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: AMG 510

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 08, 2020

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Details:

Sotorasib demonstrated an objective response rate (primary end point) consistent with previously reported Phase 1 data in patients with advanced NSCLC taking the 960 mg daily dose.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: AMG510

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 05, 2020

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Details:

Sotorasib demonstrated confirmed objective response rate (ORR) and disease control rates (DCR) of 35.3% and 91.2%, respectively, in 34 heavily pretreated patients (median of two prior lines of therapy) with NSCLC, who were treated with the 960 mg daily dose.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: AMG510

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 20, 2020

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Details:

Data from the study of sotorasib, Amgen's investigational KRASG12C inhibitor, will showcase Phase 1 clinical results on durability of clinical benefit in patients with non-small cell lung cancer (NSCLC).


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: AMG510

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 16, 2020

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Details:

The preclinical antitumor activities of repotrectinib in combination with proxy molecules for AMG510, an investigational KRAS-G12C inhibitor, and trametinib, an approved MEK inhibitor were highlighted for the first time in two poster presentations.


Lead Product(s): Repotrectinib,Sotorasib

Therapeutic Area: Oncology Product Name: TPX-0005

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 22, 2020

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Details:

The trial is an open-label, dose-escalation and dose-expansion study evaluating the safety, tolerability, pharmacokinetics, and efficacy of the combination of RMC-4630 and AMG 510 in patients with advanced solid tumors harboring the KRASG12C mutation.


Lead Product(s): Vociprotafib,Sotorasib

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Amgen Inc

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 09, 2020

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Details:

Updated Phase 1 data from patients with advanced colorectal cancer and other selected solid tumors continued to demonstrate disease control activity, safety and tolerability after AMG 510 treatment.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 29, 2020

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Details:

Presentation will highlight data evaluating sotorasib (AMG 510), a first-in-class investigational KRASG12C inhibitor, in colorectal cancer and other solid tumors. Amgen is also going present AMG 330 Data in Acute Myeloid Leukemia Highlights Innovative BiTE® Technology.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 13, 2020

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Details:

QIAGEN and Amgen to develop tissue-based therascreen® test, paired with investigational treatment AMG 510, to identify patients whose cancers have KRAS G12C mutation.


Lead Product(s): Sotorasib

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Amgen Inc

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration January 13, 2020

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