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                          01

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Beyonttra (acoramidis hydrochloride) is an orally administered near-complete stabilizer of TTR for the treatment of transthyretin amyloidosis in adult patients with cardiomyopathy.

                          Product Name : Beyonttra

                          Product Type : Miscellaneous

                          Upfront Cash : $300.0 million

                          June 30, 2025

                          Lead Product(s) : Acoramidis Hydrochloride

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : HealthCare Royalty

                          Deal Size : $300.0 million

                          Deal Type : Agreement

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                          02

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Attruby (acoramidis) is a transthyretin stabilizer being investigated for the treatment of younger patients with cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM).

                          Product Name : Attruby

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 13, 2025

                          Lead Product(s) : Acoramidis HCl,Acoramidis Hydrochloride

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          03

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Beyonttra is an orally administered stabilizer of transthyretin (TTR) indicated for the treatment of wild-type or variant transthyretin amyloidosis in adult patients with cardiomyopathy.

                          Product Name : Beyonttra

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 28, 2025

                          Lead Product(s) : Acoramidis Hydrochloride

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          04

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Beyonttra (acoramidis) is a next-generation, orally-administered, highly potent, small molecule stabiliser of transthyretin. It is approved for the treatment of Transthyretin Amyloid Cardiomyopathy.

                          Product Name : Beyonttra

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          March 27, 2025

                          Lead Product(s) : Acoramidis Hydrochloride

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Beyonttra (acoramidis) is a next-generation, orally-administered, highly potent, small molecule stabiliser of transthyretin. It is approved for the treatment of Transthyretin Amyloid Cardiomyopathy.

                          Product Name : Beyonttra

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 11, 2025

                          Lead Product(s) : Acoramidis HCl

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Attruby (acoramidis) is a next-generation, orally-administered, highly potent, small molecule stabiliser of transthyretin. It is approved for the treatment of Transthyretin Amyloid Cardiomyopathy.

                          Product Name : Beyonttra

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 13, 2024

                          Lead Product(s) : Acoramidis HCl

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Under the terms of the agreement, UNP assumed responsibility for R&D, and BridgeBio will assume the further development of the macrocyclic peptide candidates for rare diseases and oncology.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Undisclosed

                          December 03, 2024

                          Lead Product(s) : Macrocyclic Peptide

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery Platform

                          Recipient : Unnatural Products

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          08

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Beyonttra (acoramidis) is a next-generation, orally-administered, highly potent, small molecule stabiliser of transthyretin. It is approved for the treatment of Transthyretin Amyloid Cardiomyopathy.

                          Product Name : Beyonttra

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 22, 2024

                          Lead Product(s) : Acoramidis HCl

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Attruby (acoramidis) is a next-generation, orally-administered, highly potent, small molecule stabiliser of transthyretin. It is approved for the treatment of Transthyretin Amyloid Cardiomyopathy.

                          Product Name : Beyonttra

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 22, 2024

                          Lead Product(s) : Acoramidis HCl

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : BBP-418 (ribitol), an investigational oral substrate supplementation therapy, being investiated in patients with limb-girdle muscular dystrophy type 2I (LGMD2I/R9).

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 30, 2024

                          Lead Product(s) : Ribitol

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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