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Chemistry

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Also known as: 1197-21-3, Phentermine hcl, Fastin, Oby-trim, Phenteral, Tora
Molecular Formula
C10H16ClN
Molecular Weight
185.69  g/mol
InChI Key
NCAIGTHBQTXTLR-UHFFFAOYSA-N
FDA UNII
0K2I505OTV

Phentermine Hydrochloride
A central nervous system stimulant and sympathomimetic with actions and uses similar to those of DEXTROAMPHETAMINE. It has been used most frequently in the treatment of obesity.
1 2D Structure

Phentermine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-methyl-1-phenylpropan-2-amine;hydrochloride
2.1.2 InChI
InChI=1S/C10H15N.ClH/c1-10(2,11)8-9-6-4-3-5-7-9;/h3-7H,8,11H2,1-2H3;1H
2.1.3 InChI Key
NCAIGTHBQTXTLR-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C)(CC1=CC=CC=C1)N.Cl
2.2 Other Identifiers
2.2.1 UNII
0K2I505OTV
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Adipex P

2. Adipex-p

3. Adipexp

4. Duromine

5. Hydrochloride, Phentermine

6. Ionamine

7. Phentermine

2.3.2 Depositor-Supplied Synonyms

1. 1197-21-3

2. Phentermine Hcl

3. Fastin

4. Oby-trim

5. Phenteral

6. Tora

7. Ona-mast

8. Phentermyl Wyncaps

9. Obestin-30

10. 2-methyl-1-phenylpropan-2-amine Hydrochloride

11. Suprenza

12. Wilpo

13. Ona-mast Hydrochloride

14. Adipex-p

15. Ionamin

16. Zantryl

17. Alpha,alpha-dimethylphenethylamine Hydrochloride

18. Phentermine Hydrochloride [usp]

19. Mg 18370

20. S 58

21. 1,1-dimethyl-2-phenylethylamine Hydrochloride

22. 1-phenyl-2-methyl-2-aminopropane Hydrochloride

23. Nsc-44090

24. Phentermine Hydrochloride Civ

25. Phenyl-t-butylamine Hydrochloride

26. 0k2i505otv

27. Duromine

28. Dea No. 1640

29. 2-methyl-1-phenylpropan-2-amine;hydrochloride

30. Benzeneethanamine, Alpha,alpha-dimethyl, Hydrochloride

31. .alpha.,.alpha.-dimethylphenethylamine Hydrochloride

32. Wilpo (van)

33. Phentermine Hydrochloride (usp)

34. Chebi:50506

35. Alpha-methylamphetamine Hydrochloride

36. Einecs 214-821-9

37. Nsc 44090

38. Unii-0k2i505otv

39. Lomaira

40. Fastin (tn)

41. Adipex-p (tn)

42. Phenteramine Hydrochloride

43. Schembl41585

44. Mls003882563

45. Phenethylamine, Alpha,alpha-dimethyl-, Hydrochloride

46. Benzeneethanamine, Alpha,alpha-dimethyl-, Hydrochloride

47. Chembl1200912

48. Dtxsid20152550

49. Wln: Zx1&1&1r &gh

50. Bcp23776

51. Nsc44090

52. Phentermine Hydrochloride [mi]

53. Akos015891196

54. .alpha.-methylamphetamine Hydrochloride

55. Ccg-221139

56. Phentermine Hydrochloride [mart.]

57. Phentermine Hydrochloride [vandf]

58. Mg 18570

59. Phentermine Hydrochloride [usp-rs]

60. Phentermine Hydrochloride [who-dd]

61. Smr000058739

62. Phentermine Hydrochloride, >=98% (hplc)

63. 2-methyl-1-phenyl-2-propanamine Hydrochloride

64. 2-amino-2-methyl-1-phenylpropane Hydrochloride

65. D05459

66. Phentermine Hcl; Adipex P; Adipex-p; Adipexp

67. Phentermine Hydrochloride [orange Book]

68. Benzeneethanamine,.alpha.-dimethyl, Hydrochloride

69. Phentermine Hydrochloride [usp Monograph]

70. Qsymia Component Phentermine Hydrochloride

71. Phentermine Hydrochloride Component Of Qsymia

72. Q19885635

73. Benzeneethanamine, .alpha.,.alpha.-dimethyl-, Hydroch

74. Phentermine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 185.69 g/mol
Molecular Formula C10H16ClN
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Exact Mass185.0971272 g/mol
Monoisotopic Mass185.0971272 g/mol
Topological Polar Surface Area26 Ų
Heavy Atom Count12
Formal Charge0
Complexity112
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NamePhentermine hydrochloride
PubMed HealthPhentermine (By mouth)
Drug ClassesAppetite Suppressant, Centrally Acting
Drug LabelPhentermine hydrochloride USP has the chemical name of , -Dimethylphenethylamine hydrochloride. The structural formula is as follows:C10H15NHClM.W. 185.7Phentermine hydrochlor...
Active IngredientPhentermine hydrochloride
Dosage FormTablet; Capsule
RouteOral
Strength37.5mg; 30mg; 15mg
Market StatusPrescription
CompanyVintage Pharms; Aurolife Pharma; Ken Lifescience; Mirror Pharms; Sun Pharm Inds; Sandoz; Invagen Pharms; Lannett Holdings; Lannett; Mutual Pharm; Mikah Pharma; Kvk Tech; Elite Labs; Barr

2 of 4  
Drug NameSuprenza
Drug LabelSuprenza is an orally disintegrating tablet (ODT) of phentermine hydrochloride, USP. Phentermine hydrochloride is a sympathomimetic amine anorectic. Its chemical name is ,,-dimethylphenethylamine hydrochloride. The structural formula is as follow...
Active IngredientPhentermine hydrochloride
Dosage FormTablet, orally disintegrating
RouteOral
Strength37.5mg; 30mg; 15mg
Market StatusPrescription
CompanyCitius Pharms

3 of 4  
Drug NamePhentermine hydrochloride
PubMed HealthPhentermine (By mouth)
Drug ClassesAppetite Suppressant, Centrally Acting
Drug LabelPhentermine hydrochloride USP has the chemical name of , -Dimethylphenethylamine hydrochloride. The structural formula is as follows:C10H15NHClM.W. 185.7Phentermine hydrochlor...
Active IngredientPhentermine hydrochloride
Dosage FormTablet; Capsule
RouteOral
Strength37.5mg; 30mg; 15mg
Market StatusPrescription
CompanyVintage Pharms; Aurolife Pharma; Ken Lifescience; Mirror Pharms; Sun Pharm Inds; Sandoz; Invagen Pharms; Lannett Holdings; Lannett; Mutual Pharm; Mikah Pharma; Kvk Tech; Elite Labs; Barr

4 of 4  
Drug NameSuprenza
Drug LabelSuprenza is an orally disintegrating tablet (ODT) of phentermine hydrochloride, USP. Phentermine hydrochloride is a sympathomimetic amine anorectic. Its chemical name is ,,-dimethylphenethylamine hydrochloride. The structural formula is as follow...
Active IngredientPhentermine hydrochloride
Dosage FormTablet, orally disintegrating
RouteOral
Strength37.5mg; 30mg; 15mg
Market StatusPrescription
CompanyCitius Pharms

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Adrenergic Agents

Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters. (See all compounds classified as Adrenergic Agents.)


Sympathomimetics

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)


Appetite Depressants

Agents that are used to suppress appetite. (See all compounds classified as Appetite Depressants.)


Central Nervous System Stimulants

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Increased Sympathetic Activity [PE]; Sympathomimetic Amine Anorectic [EPC]; Appetite Suppression [PE]

Listed Suppliers

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  • WHO-GMP

Virtual BoothMoehs Group, a reference company in the production of pharmaceutical active ingredients.

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Phentermine Hydrochloride

About the Company : Since its founding in 1962, MOEHS has produced Active Pharmaceutical Ingredients (APIs) for the international pharmaceutical industry. Thanks to a business history of more than 50 ...

Since its founding in 1962, MOEHS has produced Active Pharmaceutical Ingredients (APIs) for the international pharmaceutical industry. Thanks to a business history of more than 50 years, MOEHS has considerable technical experience in the production of these substances. At Moehs Group we have a large tradition and experience in the area of manufacturing of active pharmaceutical and veterinary ingredients, agrochemicals, nutraceutical, cosmetic, as well as fine chemistry in general, with high levels of quality and safety standards-GMP´s, ICH, approved by the FDA and TGA.
Moehs Iberica

02

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothTenatra connects Indian manufacturers with global buyers through active partners in Germany, Switzerland, Belgium, Spain & Turkey.

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Phentermine Hydrochloride

About the Company : Tenatra International was established as a proprietorship firm in 1999. It got off to a very good start, supporting clients in the United States, Mexico and Europe. As business opp...

Tenatra International was established as a proprietorship firm in 1999. It got off to a very good start, supporting clients in the United States, Mexico and Europe. As business opportunities grew, it was felt that the proprietorship firm had outlived its usefulness and that it needed a corporate structure. So, Tenatra Chemie Private Limited (TCPL) was incorporated in 2002. Since then, the company has come a long way, gaining valuable experience and knowledge in the fields of chemicals and pharmaceuticals in India.
Tenatra

03

Biotechnica DWC

Algeria
STLE Annual Meeting
Not Confirmed
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Biotechnica DWC

Algeria
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STLE Annual Meeting
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Phentermine Hydrochloride

About the Company : BIOTECHNICA DWC LLC has carved a niche for itself in providing value added compliance, regulatory qualification, project management and GDP guidance services to pharma companies al...

BIOTECHNICA DWC LLC has carved a niche for itself in providing value added compliance, regulatory qualification, project management and GDP guidance services to pharma companies all over the world. Biotechnica is an integrated global solution provider from design to implementation of industrial projects in the areas of Pharmaceuticals,Agri-food ,Cosmetics and Nutrition. With more than 25 years of experience in the assembly of plants, particularly in the pharmaceutical sector, we accompany our customers in the various stages of their projects – E-CTD Dossieers – Raw Materiels – Equipements – Accessories – Packaging – Distribution.
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04

Olon S.p.A

Italy
STLE Annual Meeting
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Olon S.p.A

Italy
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STLE Annual Meeting
Not Confirmed

Phentermine Hydrochloride

About the Company : We produce Active Pharmaceutical Ingredients (APIs) providing integrated full-service capabilities. Olon’s ability to develop and manufacture Active Pharmaceutical Ingredients (...

We produce Active Pharmaceutical Ingredients (APIs) providing integrated full-service capabilities. Olon’s ability to develop and manufacture Active Pharmaceutical Ingredients (APIs) in our network of facilities allows clients full access to integrated services resulting in faster production and delivery timelines, with one of the most extensive track records. We rely on synthetic and biological processes both for generic and contract development and the manufacturing market, in a full cGMPs environment, following ICH Q7 compliance.
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Siegfried AG

Switzerland
STLE Annual Meeting
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Siegfried AG

Switzerland
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STLE Annual Meeting
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Phentermine Hydrochloride

About the Company : As an internationally renowned outsourcing partner, we offer products and tailor-made service packages that are seamlessly embedded in the value chain of our customers. Our pharmac...

As an internationally renowned outsourcing partner, we offer products and tailor-made service packages that are seamlessly embedded in the value chain of our customers. Our pharmaceutical industry partners benefit from a wide range of offers - from the development of active ingredients to development services for ready-made drugs, their approval and production to packaging and logistics. As a former fully integrated pharmaceutical company, Siegfried is now one of the few suppliers who can develop both active ingredients and ready-made drugs under one roof. This combination of experience and know-how is unique in the CDMO market.
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06

Symed Labs

India
STLE Annual Meeting
Not Confirmed
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Symed Labs

India
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STLE Annual Meeting
Not Confirmed

Phentermine Hydrochloride

About the Company : Symed Labs Ltd is a leading Hyderabad based manufacturer of Active Pharmaceutical Ingredients (APIs) and an end-to-end solution provider for the pharmaceutical industry for chemist...

Symed Labs Ltd is a leading Hyderabad based manufacturer of Active Pharmaceutical Ingredients (APIs) and an end-to-end solution provider for the pharmaceutical industry for chemistry related services. We are more than 300 employees strong and our core competence is in the application of strong process chemistry to manufacturing in a regulatory environment. For the past 15 years, Symed has been at the forefront of facilitating and accelerating drug development (and GMP manufacturing) of APIs. The company's technical and scientific teams provide reliable solutions and services to the global pharmaceutical industry.
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API Reference Price

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LTD","customerCountry":"INDIA","quantity":"64.00","actualQuantity":"64","unit":"KGS","unitRateFc":"431.7","totalValueFC":"28008.5","currency":"N\/A","unitRateINR":"37906.7","date":"10-Mar-2025","totalValueINR":"2426026.38","totalValueInUsd":"28008.5","indian_port":"Bombay Air","hs_no":"29214600","bill_no":"8809847","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"ZURICH","supplierAddress":"SUITE 305 10 NORBRIK DRIVE BELLA VISTA, NSW 2153 UNITED STATES","customerAddress":"A 204, NEELAM CENTRE"}]
27-Jan-2021
10-Mar-2025
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DOSAGE - TABLET;ORAL - 37.5MG

USFDA APPLICATION NUMBER - 85128

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DOSAGE - CAPSULE;ORAL - 30MG

USFDA APPLICATION NUMBER - 86945

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DOSAGE - CAPSULE;ORAL - 15MG

USFDA APPLICATION NUMBER - 87190

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DOSAGE - CAPSULE;ORAL - 30MG

USFDA APPLICATION NUMBER - 87190

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DOSAGE - CAPSULE;ORAL - 37.5MG

USFDA APPLICATION NUMBER - 88023

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ABOUT THIS PAGE

Looking for 1197-21-3 / Phentermine Hydrochloride API manufacturers, exporters & distributors?

Phentermine Hydrochloride manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Phentermine Hydrochloride API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Phentermine Hydrochloride manufacturer or Phentermine Hydrochloride supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Phentermine Hydrochloride manufacturer or Phentermine Hydrochloride supplier.

PharmaCompass also assists you with knowing the Phentermine Hydrochloride API Price utilized in the formulation of products. Phentermine Hydrochloride API Price is not always fixed or binding as the Phentermine Hydrochloride Price is obtained through a variety of data sources. The Phentermine Hydrochloride Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Phentermine Hydrochloride

Synonyms

1197-21-3, Phentermine hcl, Fastin, Oby-trim, Phenteral, Tora

Cas Number

1197-21-3

Unique Ingredient Identifier (UNII)

0K2I505OTV

About Phentermine Hydrochloride

A central nervous system stimulant and sympathomimetic with actions and uses similar to those of DEXTROAMPHETAMINE. It has been used most frequently in the treatment of obesity.

Phentermine Hydrochloride Manufacturers

A Phentermine Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Phentermine Hydrochloride, including repackagers and relabelers. The FDA regulates Phentermine Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Phentermine Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Phentermine Hydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Phentermine Hydrochloride Suppliers

A Phentermine Hydrochloride supplier is an individual or a company that provides Phentermine Hydrochloride active pharmaceutical ingredient (API) or Phentermine Hydrochloride finished formulations upon request. The Phentermine Hydrochloride suppliers may include Phentermine Hydrochloride API manufacturers, exporters, distributors and traders.

click here to find a list of Phentermine Hydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Phentermine Hydrochloride USDMF

A Phentermine Hydrochloride DMF (Drug Master File) is a document detailing the whole manufacturing process of Phentermine Hydrochloride active pharmaceutical ingredient (API) in detail. Different forms of Phentermine Hydrochloride DMFs exist exist since differing nations have different regulations, such as Phentermine Hydrochloride USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Phentermine Hydrochloride DMF submitted to regulatory agencies in the US is known as a USDMF. Phentermine Hydrochloride USDMF includes data on Phentermine Hydrochloride's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Phentermine Hydrochloride USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Phentermine Hydrochloride suppliers with USDMF on PharmaCompass.

Phentermine Hydrochloride KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Phentermine Hydrochloride Drug Master File in Korea (Phentermine Hydrochloride KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Phentermine Hydrochloride. The MFDS reviews the Phentermine Hydrochloride KDMF as part of the drug registration process and uses the information provided in the Phentermine Hydrochloride KDMF to evaluate the safety and efficacy of the drug.

After submitting a Phentermine Hydrochloride KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Phentermine Hydrochloride API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Phentermine Hydrochloride suppliers with KDMF on PharmaCompass.

Phentermine Hydrochloride WC

A Phentermine Hydrochloride written confirmation (Phentermine Hydrochloride WC) is an official document issued by a regulatory agency to a Phentermine Hydrochloride manufacturer, verifying that the manufacturing facility of a Phentermine Hydrochloride active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Phentermine Hydrochloride APIs or Phentermine Hydrochloride finished pharmaceutical products to another nation, regulatory agencies frequently require a Phentermine Hydrochloride WC (written confirmation) as part of the regulatory process.

click here to find a list of Phentermine Hydrochloride suppliers with Written Confirmation (WC) on PharmaCompass.

Phentermine Hydrochloride NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Phentermine Hydrochloride as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Phentermine Hydrochloride API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Phentermine Hydrochloride as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Phentermine Hydrochloride and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Phentermine Hydrochloride NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Phentermine Hydrochloride suppliers with NDC on PharmaCompass.

Phentermine Hydrochloride GMP

Phentermine Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Phentermine Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Phentermine Hydrochloride GMP manufacturer or Phentermine Hydrochloride GMP API supplier for your needs.

Phentermine Hydrochloride CoA

A Phentermine Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Phentermine Hydrochloride's compliance with Phentermine Hydrochloride specifications and serves as a tool for batch-level quality control.

Phentermine Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Phentermine Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Phentermine Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Phentermine Hydrochloride EP), Phentermine Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Phentermine Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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