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Details:

GMRx2 is a single-pill, multi-mechanism, triple combination of telmisartan, amlodipine and indapamide, in novel and proprietary dosage strengths and is in Phase III development for hypertension and for the prevention of recurrent intracerebral haemorrhage.


Lead Product(s): Telmisartan,Amlodipine,Indapamide

Therapeutic Area: Cardiology/Vascular Diseases Product Name: GMRx2

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 12, 2023

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GMRx2 is George Medicine’s most advanced candidate in late-stage development. A single-pill triple combination, it contains low doses of the commonly used hypertension medications telmisartan, amlodipine and indapamide.


Lead Product(s): Telmisartan,Amlodipine,Indapamide

Therapeutic Area: Cardiology/Vascular Diseases Product Name: GMRx2

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 07, 2022

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The agreement outlines a transition period during which Daiichi Sankyo and Cosette will transfer responsibilities for the manufacture and commercialization of Azor, Benicar, Effient and other products, including quality assurance, pharmacovigilance and regulatory matters.


Lead Product(s): Amlodipine,Olmesartan Medoxomil

Therapeutic Area: Cardiology/Vascular Diseases Product Name: Azor

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Cosette Pharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Divestment January 18, 2022

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GMRx2 is a single pill triple combination in novel and proprietary dosage strengths containing telmisartan, amlodipine and indapamide, targeted for first line therapy to control hypertension.


Lead Product(s): Telmisartan,Amlodipine,Indapamide

Therapeutic Area: Cardiology/Vascular Diseases Product Name: GMRx2

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 01, 2021

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Pfizer and Mylan have received clearance from the US FTC to advance the merger of Pfizer’s Upjohn generics unit and Mylan. As part of the FTC clearance, the companies need to divest seven products before moving forward with the merger, this includes Upjohn’s Caduet.


Lead Product(s): Amlodipine,Atorvastatin

Therapeutic Area: Cardiology/Vascular Diseases Product Name: Caduet

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Viatris

Deal Size: $12,000.0 million Upfront Cash: Undisclosed

Deal Type: Merger November 16, 2020

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