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    Grapiprant

    ACTIVE PHARMA INGREDIENTS

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    Looking for 415903-37-6 / Grapiprant API manufacturers, exporters & distributors?

    Grapiprant manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Grapiprant API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Grapiprant manufacturer or Grapiprant supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Grapiprant manufacturer or Grapiprant supplier.

    API | Excipient name

    Grapiprant

    Synonyms

    415903-37-6, Cj-023423, Aat-007, Cj 023423, Rq-7, Rq-00000007

    Cas Number

    415903-37-6

    Unique Ingredient Identifier (UNII)

    J9F5ZPH7NB

    About Grapiprant

    Grapiprant is an orally bioavailable antagonist of the prostaglandin E receptor subtype 4 (EP4), with potential analgesic, immunomodulating and antineoplastic activities. Upon administration of grapiprant, this agent selectively binds to and inhibits the binding of prostaglandin E2 (PGE2) and prevents the activation of the EP4 receptor. This inhibits PGE2-EP4 receptor-mediated signaling and prevents proliferation in tumor cells in which the PGE2-EP4 signaling pathway is over-activated. In addition, EP4 receptor inhibition modulates the immune system by preventing both interleukin-23 (IL-23) production and the IL-23-mediated expansion of Th17 cells. As EP4 is expressed by peripheral sensory neurons, blockade of EP4-mediated signaling may induce an analgesic effect. EP4, a prostanoid receptor subtype, is a G protein-coupled receptor that is expressed in certain types of cancers; it promotes tumor cell proliferation and invasion.

    Grapiprant Manufacturers

    A Grapiprant manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Grapiprant, including repackagers and relabelers. The FDA regulates Grapiprant manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Grapiprant API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Grapiprant manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

    Grapiprant Suppliers

    A Grapiprant supplier is an individual or a company that provides Grapiprant active pharmaceutical ingredient (API) or Grapiprant finished formulations upon request. The Grapiprant suppliers may include Grapiprant API manufacturers, exporters, distributors and traders.

    click here to find a list of Grapiprant suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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