MELBOURNE, Australia, Nov. 2, 2023 /PRNewswire/ -- PolyActiva is a Melbourne-based ophthalmology company developing a novel proprietary drug delivery platform. Today the company reported promising interim results from an ongoing Phase 2a clinical study for its PA5108 Ocular Implant in subjects with mild to moderate glaucoma. This ocular implant is designed to deliver 6 months of latanoprost and to biodegrade, allowing for repeat dosing. In the initial cohort, PA5108 showed a >20% reduction in intraocular pressure (IOP) at 12 weeks and 26 weeks. In a further cohort, the implant's rapid biodegradation profile has also allowed for eight (8) patients thus far to receive a second implant at 21 weeks, providing ongoing, uninterrupted therapy, with no product related adverse effects.
MELBOURNE, Australia, March 4, 2022 /PRNewswire/ -- PolyActiva Pty Ltd, a clinical-stage Australian biopharmaceutical company focused on developing unique biodegradable ocular implants with sustained drug delivery for patients suffering from ophthalmic diseases such as glaucoma, today announced that data from the Phase IIa study of its PA5108 Ocular Implant for the treatment of Primary Open-Angle Glaucoma (POAG) will be presented at the 2022 American Glaucoma Society (AGS) Annual Meeting. The conference is taking place March 3-6, 2022 in Nashville, TN.