Fierce Biotech may have only broken the story of Goldfinch Bio’s demise last Friday, but Karuna Therapeutics has already raced to the closing down sale to take its pick from the shuttered biotech’s pipeline.
CEO Tony Johnson and Chief Financial and Operating Officer Kyle Kuvalanka told Fierce Biotech that the company is closing up shop after failing to secure additional financing. Goldfinch is now in an assignment for the benefit of creditors in Delaware court, an alternative to bankruptcy.
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Goldfinch Bio, Inc., a clinical stage biotechnology company focused on discovering and developing precision medicines for the treatment of kidney diseases, today announced the publication of data validating transplanted, perfused human kidney organoids as a novel, predictive and translatable preclinical PD model for use in kidney disease drug development. This breakthrough approach was initially validated with the company’s lead drug candidate, GFB-887, a selective Transient Receptor Potential Canonical Channel 5 (TRPC5) inhibitor, which, since this original organoid work, demonstrated clinical proof of concept in a Phase 2 study in patients with FSGS. The manuscript, titled “Transplanted organoids empower human preclinical assessment of drug candidate for the clinic,” is available online in the international peer-reviewed journal Science Advances at: https://www.science.org/doi/10.1126/sciadv.abj5633.
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Goldfinch Bio, a clinical stage biotechnology company focused on discovering and developing precision medicines for the treatment of kidney diseases, today announced that it will present initial data from its Phase 1 clinical trial of GFB-024 in a poster presentation at the American Diabetes Association (ADA) 82nd Scientific Sessions, taking place June 3-7 in New Orleans, LA, and an oral presentation at the Endocrine Society’s Annual Meeting, ENDO 2022, taking place June 11-14 in Atlanta, GA. Both meetings also have a virtual component.
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Goldfinch Bio, a clinical stage biotechnology company focused on discovering and developing precision medicines for the treatment of kidney diseases, today announced that it will host a virtual event to discuss the unmet need in focal segmental glomerular sclerosis (FSGS), as well as the recently announced clinical data from TRACTION-2, the ongoing Phase 2 trial evaluating GFB-887 as a precision medicine for the treatment of FSGS. GFB-887 is a podocyte-targeting, small molecule inhibitor of Transient Receptor Potential Canonical Channel 5 (TRPC5). The event will be held on Tuesday, March 29, 2022, beginning at 4:00 p.m. ET.
Goldfinch Bio’s kidney disease treatment quelled rising protein levels in patients’ urine, but only in one of the two diseases being tested, according to initial data from a phase 2 trial.
VANCOUVER, British Columbia--(BUSINESS WIRE)--REVITALIST LIFESTYLE AND WELLNESS LTD. (“Revitalist” or the “Company”) (CSE: CALM) (OTCQB: RVLWF) (FSE: 4DO) is pleased to announce its collaboration with PharmaTher Holdings Ltd. (“PharmaTher”) (CSE: PHRM) (O
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Goldfinch Bio, a clinical stage biotechnology company focused on discovering and developing precision medicines for the treatment of kidney diseases, today announced its participation in the following upcoming scientific and investor conferences.
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Goldfinch Bio, a clinical stage biotechnology company focused on discovering and developing precision medicines for the treatment of kidney diseases, today announced that it has dosed the first patient in an open-label extension study for patients with focal segmental glomerular sclerosis (FSGS) enrolled in its Phase 2 TRACTION-2 clinical trial of GFB-887, a highly potent and selective inhibitor of Transient Receptor Potential Canonical Channel 5 (TRPC5)1. Anticipated to enroll approximately 35 patients, the extension study is designed to evaluate the long-term safety and tolerability of GFB-887.
Goldfinch Bio, a clinical stage biotechnology company focused on discovering and developing precision medicines for the treatment of kidney diseases, today announced that Anthony Johnson, M.D., President and Chief Executive Officer of Goldfinch Bio, will participate in a panel discussion, Casino Re-nal Part 1 – Novel Mechanisms in Renal Disorders, at the Wedbush PacGrow Healthcare Virtual Conference on Tuesday, August 10, 2021 at 3:30 p.m. ET.