Gossamer Bio’s GB001 has failed in two midphase trials in asthma and chronic rhinosinusitis. The failures come months after Novartis dumped rival DP2 inhibitor fevipiprant in response to a clutch of phase 3 flops.
Novartis’ fevipiprant has failed another pair of phase 3 clinical trials, prompting the Swiss pharma to halt further development in asthma.
The negative top-line data deal a big blow to the prospects of a drug analysts tipped to achieve blockbuster sales if it cleared phase 3.
Every Big Pharma company is judged by its late-stage pipeline and the number of prospective blockbusters in play. Novartis CEO Vas Narasimhan is giving his pivotal strategy top marks today as the giant player reviews its development game plan in the wake of a couple of key setbacks.