BURLINGTON, Mass. & OXFORD, England--(BUSINESS WIRE)--Blue Earth Diagnostics, a Bracco company and recognized leader in the development and commercialization of innovative PET radiopharmaceuticals, today announced results of a secondary, post-hoc analysis of data from the prospective LOCATE and FALCON clinical trials that evaluated the impact of Axumin® (fluciclovine F 18) PET/CT imaging on management of patients with recurrent prostate cancer. This analysis characterized the impact of Axumin PET/CT on sites of disease recurrence and plans for androgen deprivation therapy (ADT) in patients with biochemical recurrence of prostate cancer. Of 146 patients who had a pre-scan plan for ADT, Axumin PET/CT detected lesions in 85 (58%) of patients. Detection rates in the prostate/bed, pelvic lymph nodes, extra-pelvic lymph nodes, soft tissue and bone were 30% (44/146), 25% (37/146), 13% (19/146), 2.1% (3/146) and 13% (19/146), respectively. Among the 146 patients with a pre-scan plan for ADT, 64% (93/146) had a change in their management plan following an Axumin scan. Of those whose management plan changed, 59% (55/93) avoided or delayed ADT. Of 60 patients originally planned for ADT monotherapy, only 25% (15) were still due to receive ADT monotherapy after Axumin PET/CT imaging. Axumin, a novel amino acid-based radiopharmaceutical, is FDA-approved for PET imaging in men with suspected prostate cancer recurrence based on elevated blood prostate specific antigen (PSA) levels following prior treatment. The secondary analysis is based on the Axumin LOCATE and FALCON trials, which have safety profiles consistent with that described in the approved U.S. Prescribing Information.