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                          Top Deals by Deal Size (USD bn)

                          01

                          AMWC Asia-TDAC
                          Not Confirmed
                          AMWC Asia-TDAC
                          Not Confirmed

                          Details : The funding will be used to evaluate Stealth's mitochondria-targeted molecule, SBT-272, a novel investigational small molecule that targets cardiolipin, a phospholipid within the inner mitochondrial membrane, for Parkinson's disease

                          Product Name : SBT-272

                          Product Type : Other Large Molecule

                          Upfront Cash : Undisclosed

                          September 08, 2023

                          Lead Product(s) : SBT-272

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Michael J. Fox Foundation for Parkinson’s Research

                          Deal Size : Undisclosed

                          Deal Type : Funding

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                          02

                          AMWC Asia-TDAC
                          Not Confirmed
                          AMWC Asia-TDAC
                          Not Confirmed

                          Details : SBT-272 significantly improved mitochondrial structural integrity and motility in TDP-43 mutant (A315T)-expressing upper motor neurons. These enhancements in mitochondrial health were associated with improved axon outgrowth, a key indicator of improved n...

                          Product Name : SBT-272

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          August 06, 2022

                          Lead Product(s) : SBT-272

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          AMWC Asia-TDAC
                          Not Confirmed
                          AMWC Asia-TDAC
                          Not Confirmed

                          Details : Interim results from the Phase 1 study for SBT-272 demonstrated that selected doses are anticipated to result in therapeutic concentrations in the brain based on observed drug levels achieved in preclinical studies.

                          Product Name : SBT-272

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          January 11, 2022

                          Lead Product(s) : SBT-272

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          AMWC Asia-TDAC
                          Not Confirmed
                          AMWC Asia-TDAC
                          Not Confirmed

                          Details : Systemic administration of SBT-272 in rodents resulted in sustained SBT-272 levels across different regions of the brain and protected mitochondria against ischemic stress, confirming that the compound crosses the blood brain barrier and has mitoprotecti...

                          Product Name : SBT-272

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          July 10, 2021

                          Lead Product(s) : SBT-272

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          AMWC Asia-TDAC
                          Not Confirmed
                          AMWC Asia-TDAC
                          Not Confirmed

                          Details : The Company expects to use proceeds from this capital raise to advance the Company's ongoing development of its lead candidate, elamipretide, its next-generation clinical stage compound, SBT-272.

                          Product Name : SBT-272

                          Product Type : Other Large Molecule

                          Upfront Cash : Undisclosed

                          April 13, 2020

                          Lead Product(s) : SBT-272

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Morningside Ventures

                          Deal Size : $20.0 million

                          Deal Type : Financing

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                          06

                          AMWC Asia-TDAC
                          Not Confirmed
                          AMWC Asia-TDAC
                          Not Confirmed

                          Details : Second Generation Mitochondrial Targeted Candidate Enters Clinic with Potential to Treat Neurodegenerative Diseases.

                          Product Name : SBT-272

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          January 21, 2020

                          Lead Product(s) : SBT-272

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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