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Find Clinical Drug Pipeline Developments & Deals for RBN-2397

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                          Top Deals by Deal Size (USD bn)

                          01

                          Iran Expo
                          Not Confirmed
                          Iran Expo
                          Not Confirmed

                          Details : Ribon plans to use the proceeds to support clinical development of its potentially first-in-class oral small molecule programs in oncology (RBN-2397, a PARP7 inhibitor) and immunology (RBN-3143, a PARP14 inhibitor).

                          Product Name : RBN-2397

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 30, 2023

                          Lead Product(s) : RBN-2397,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Pfizer Inc

                          Deal Size : $25.0 million

                          Deal Type : Financing

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                          02

                          Iran Expo
                          Not Confirmed
                          Iran Expo
                          Not Confirmed

                          Details : RBN-2397 is an orally available small molecule inhibitor of PARP7 being developed for the treatment cancer. RBN-2397 has been shown to directly inhibit cellular proliferation and restore interferon signaling to stimulate an innate and adaptive antitumor ...

                          Product Name : RBN-2397

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 29, 2022

                          Lead Product(s) : RBN-2397,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Iran Expo
                          Not Confirmed
                          Iran Expo
                          Not Confirmed

                          Details : Ono will have the exclusive rights to develop and commercialize RBN-2397 in the Ono Territory. Additionally, Ono will have the right to participate in global clinical studies of RBN-2397 by bearing the costs of such studies in the Ono Territory.

                          Product Name : RBN-2397

                          Product Type : Other Small Molecule

                          Upfront Cash : $16.3 million

                          February 02, 2021

                          Lead Product(s) : RBN-2397

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Ono Pharmaceutical

                          Deal Size : $148.3 million

                          Deal Type : Collaboration

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                          04

                          Iran Expo
                          Not Confirmed
                          Iran Expo
                          Not Confirmed

                          Details : RBN-2397 restores type I IFN signaling in the tumor, causes complete tumor regressions and adaptive immunity in preclinical models.

                          Product Name : RBN-2397

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 15, 2020

                          Lead Product(s) : RBN-2397

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Iran Expo
                          Not Confirmed
                          Iran Expo
                          Not Confirmed

                          Details : This presentation will highlight 3 ongoing clinical activities of the company which includes data on a selective PARP14 Inhibitor and RBN-2397 in Treatment of cancer.

                          Product Name : RBN-2397

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 14, 2020

                          Lead Product(s) : RBN-2397

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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