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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Dexmedetomidine Hydrochloride,Inapplicable

                          Therapeutic Area : Neurology

                          Study Phase : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Dr. Reddy’s Dexmedetomidine Hydrochloride in 0.9% Sodium Chloride Injection is available in 200 mcg/50 mL (4 mcg/mL) and 400 mcg/100 mL (4 mcg/mL) in 50 mL and 100 mL clear glass vials, respectively.

                          Product Name : Dexmedetomidine Hydrochloride-Generic

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 25, 2020

                          Lead Product(s) : Dexmedetomidine Hydrochloride,Inapplicable

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Dr Reddy Company Banner

                          02

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 23, 2019

                          Lead Product(s) : Dexmedetomidine Hydrochloride,Inapplicable

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase IV

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Fermion Orion Company Banner

                          03

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Strengthened cash position will support advancement of SERENITY trial, to evaluate BXCL501, an ODT of dexmedetomidine, for agitation associated with bipolar disorders or schizophrenia.

                          Product Name : Igalmi

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          March 11, 2025

                          Lead Product(s) : Dexmedetomidine Hydrochloride,Inapplicable

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : $14.0 million

                          Deal Type : Financing

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                          04

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : An orally dissolving film formulation of BXCL501 (dexmedetomidine), in the at-home setting is being investigated for acute treatment of agitation associated with bipolar disorders or schizophrenia.

                          Product Name : Igalmi

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 07, 2025

                          Lead Product(s) : Dexmedetomidine Hydrochloride,Inapplicable

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          05

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The proceeds from the financing will be used to commercialize Igalmi (dexmedetomidine HCl). It is being indicated for the treatment of agitation associated with schizophrenia.

                          Product Name : Igalmi

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          March 04, 2025

                          Lead Product(s) : Dexmedetomidine Hydrochloride,Inapplicable

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Approved FDF

                          Sponsor : Rodman & Renshaw LLC

                          Deal Size : $14.0 million

                          Deal Type : Public Offering

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                          06

                          Lone Baandrup

                          Country arrow
                          EPSC
                          Not Confirmed

                          Lone Baandrup

                          Country arrow
                          EPSC
                          Not Confirmed

                          Lead Product(s) : Dexmedetomidine Hydrochloride,Midazolam

                          Therapeutic Area : Psychiatry/Psychology

                          Study Phase : Phase II/ Phase III

                          Sponsor : Copenhagen University Hospital - Bispebjerg and Frederiksberg Hospital | Capital Region Pharmacy, Denmark

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 30, 2024

                          Lead Product(s) : Dexmedetomidine Hydrochloride,Midazolam

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Copenhagen University Hospital - Bispebjerg and Frederiksberg Hospital | Capital Region Pharmacy, Denmark

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : BXCL501 (dexmedetomidine Hc;) is being evaluated in the late-stage clinical trials studies for the treatment of Agitation Associated with Bipolar Disorders and Schizophrenia.

                          Product Name : Igalmi

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 11, 2024

                          Lead Product(s) : Dexmedetomidine Hydrochloride,Inapplicable

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Sponsor : CSL Vifor

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : A generic version of Precedex (dexmedetomidine hydrochloride), an alpha2-adrenergic agonist with sedative properties used for short-term intravenous sedation.

                          Product Name : Precedex-Generic

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 18, 2024

                          Lead Product(s) : Dexmedetomidine Hydrochloride,Inapplicable

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : BXCL501 (dexmedetomidine HCl) is an adrenergic receptor alpha-2 agonist, small molecule drug candidate, which is currently being evaluated for agitation associated With alzheimer’s dementia.

                          Product Name : Igalmi

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 04, 2024

                          Lead Product(s) : Dexmedetomidine Hydrochloride,Inapplicable

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal

                          Country arrow
                          EPSC
                          Not Confirmed

                          Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal

                          Country arrow
                          EPSC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 01, 2024

                          Lead Product(s) : Dexmedetomidine Hydrochloride,Inapplicable

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Canadian Critical Care Trials Group

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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