
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : ATAI Life Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PCN-101 (R-ketamine), a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, is a single isomer of ketamine and belongs to a new generation of glutamate receptor modulators with the potential for rapid-acting antidepressant activity and anti-...
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
August 08, 2023
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : ATAI Life Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PCN-101 is a single isomer of ketamine and belongs to a new generation of glutamate receptor modulators with the potential for rapid-acting antidepressant (RAAD) activity and anti-suicidal effects. Pharmacologically, PCN-101 is a non-competitive NMDA rec...
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
October 25, 2022
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Precision For Medicine | IQVIA
Deal Size : Inapplicable
Deal Type : Inapplicable
A Randomized, Placebo-Controlled, Double-Blind Study to Assess Safety and Efficacy of PCN-101 in TRD
Details : PCN-101 is a Controlled Substance drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Depressive Disorder, Treatment-Resistant.
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
June 10, 2022
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Precision For Medicine | IQVIA
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Company initiate, Phase 2a clinical study to evaluate the safety and efficacy of PCN-101 (R-ketamine), a stereoisomer of ketamine being developed for therapeutic treatment of psychiatric disorders such as TRD.
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
September 14, 2021
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Otsuka Pharmaceutical
Deal Size : Undisclosed
Deal Type : Collaboration
Perception and Otsuka Enter Collaboration and Licensing Deal for Depression Drug Candidate
Details : Under the terms of the license, Otsuka will have exclusive rights to develop and commercialize products containing PCN-101 in Japan. Otsuka will undertake development, regulatory, and commercialization activities in Japan, with input and guidance from bo...
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : $20.0 million
March 16, 2021
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Otsuka Pharmaceutical
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PCN-101 was safe and well-tolerated at all doses up to 150 mg, the highest dose tested. There were no serious adverse events reported. The pharmacokinetics of PCN-101 in plasma were approximately dose-proportional.
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
February 19, 2021
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
