
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : ORKA-002
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Viking Global Investors
Deal Size : $180.0 million
Deal Type : Private Placement
Oruka Therapeutics Announces $180 Million Private Placement
Details : The Company intends to use the net proceeds for research and development, including ORKA-002, a novel, extended half-life monoclonal antibody targeting IL-17A/F.
Product Name : ORKA-002
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
September 17, 2025
Lead Product(s) : ORKA-002
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Viking Global Investors
Deal Size : $180.0 million
Deal Type : Private Placement

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Lead Product(s) : ORKA-001
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ORKA-001 Versus Placebo in Patients with Moderate-to-Severe Plaque Psoriasis
Details : ORKA-001 is a Antibody drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Psoriasis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
July 29, 2025
Lead Product(s) : ORKA-001
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ORKA-002
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ORKA-002-211 A Phase I Study to Evaluate ORKA-002 in Healthy Volunteers Following A Single Dose
Details : ORKA-002 is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
April 25, 2025
Lead Product(s) : ORKA-002
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ORKA-002
Therapeutic Area : Dermatology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Oruka Therapeutics Announces Preclinical Data for ORKA-002
Details : ORKA-002 is a novel, subcutaneously administered, half-life extended monoclonal antibody targeting IL-17A/F. It is being evaluated for the treatment of plaque psoriasis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
March 07, 2025
Lead Product(s) : ORKA-002
Therapeutic Area : Dermatology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ORKA-001
Therapeutic Area : Dermatology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Oruka Doses First Participants in Phase 1 Trial of ORKA-001 Anti-IL-23p19 Antibody
Details : ORKA-001 is a IL-23p19 inhibitor, antibody. It is currently being evaluated in early-stage clinical trials for the treatment of psoriasis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
December 19, 2024
Lead Product(s) : ORKA-001
Therapeutic Area : Dermatology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ORKA-001
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ORKA-001 in Healthy Volunteers
Details : ORKA-001 is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 21, 2024
Lead Product(s) : ORKA-001
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ORKA-001
Therapeutic Area : Dermatology
Study Phase : IND Enabling
Sponsor : Braidwell LP
Deal Size : $200.0 million
Deal Type : Private Placement
Oruka Therapeutics Announces $200 Million Private Placement
Details : The net proceeds from the financing will be used to support the clinical development of ORKA-001, currently being evaluated in early-stage clinical trials for the treatment of psoriasis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
September 12, 2024
Lead Product(s) : ORKA-001
Therapeutic Area : Dermatology
Highest Development Status : IND Enabling
Sponsor : Braidwell LP
Deal Size : $200.0 million
Deal Type : Private Placement

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Lead Product(s) : ORKA-001
Therapeutic Area : Dermatology
Study Phase : IND Enabling
Sponsor : Oruka Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
ARCA Biopharma Completes Merger with Oruka Therapeutics, Implements Stock Split
Details : Through the merger, the company will focus on advancing Oruka’s pipeline of potentially best-in-class biologics, including ORKA-001 (an IL-23p19 inhibitor) for the treatment of plaque psoriasis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
August 29, 2024
Lead Product(s) : ORKA-001
Therapeutic Area : Dermatology
Highest Development Status : IND Enabling
Sponsor : Oruka Therapeutics
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : ORKA-001
Therapeutic Area : Dermatology
Study Phase : IND Enabling
Sponsor : Oruka Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
ARCA biopharma and Oruka Therapeutics Announce Merger Agreement
Details : Through the merger, the company will focus on advancing Oruka’s pipeline of potentially best-in-class biologics, including ORKA-001 (an IL-23p19 inhibitor) for the treatment of plaque psoriasis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
April 03, 2024
Lead Product(s) : ORKA-001
Therapeutic Area : Dermatology
Highest Development Status : IND Enabling
Sponsor : Oruka Therapeutics
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : ORKA-001
Therapeutic Area : Dermatology
Study Phase : IND Enabling
Sponsor : Fairmount Funds Management LLC
Deal Size : $275.0 million
Deal Type : Private Placement
ARCA biopharma and Oruka Therapeutics Announce Merger Agreement
Details : The net proceeds will be used to advance Oruka’s pipeline of potentially best-in-class biologics, including ORKA-001 (an IL-23p19 inhibitor) for the treatment of plaque psoriasis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
April 03, 2024
Lead Product(s) : ORKA-001
Therapeutic Area : Dermatology
Highest Development Status : IND Enabling
Sponsor : Fairmount Funds Management LLC
Deal Size : $275.0 million
Deal Type : Private Placement
