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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : Rohto Pharmaceutical

                          Deal Size : Undisclosed

                          Deal Type : Partnership

                          Details : RELISTOR® (methylnaltrexone bromide) is an opioid antagonist. RELISTOR tablets and RELISTOR injection are indicated for the treatment of opioid-induced constipation (OIC) in adults with chronic non-cancer pain.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          June 24, 2022

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Rohto Pharmaceutical

                          Deal Size : Undisclosed

                          Deal Type : Partnership

                          Bloomage Company Banner

                          02

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Adagene is providing a proprietary antibody to ConjugateBio, which will use it to develop novel bispecific antibody-drug conjugates (ADCs) targeting solid tumors.

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          July 08, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : ConjugateBio

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          03

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Under the licensing agreement, Juri will hold the exclusive global rights to a development-ready T-cell engager targeting KLK2/CD3 for the treatment of metastatic prostate cancer.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          May 27, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Juri Biosciences

                          Deal Size : $210.0 million

                          Deal Type : Licensing Agreement

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                          04

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : The collaboration aims to evaluate the combination of ATG-022, a CLDN18.2-targeting ADC, and MSD's anti-PD-1 therapy, Keytruda in patients with advanced solid tumors.

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          May 21, 2025

                          Lead Product(s) : ATG-022,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Merck & Co

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Under the terms of the agreement, Lepu Biopharma has granted ArriVent exclusive global rights to develop, manufacture and commercialize MRG007 outside of Greater China.

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : $47.0 million

                          January 21, 2025

                          Lead Product(s) : MRG007

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Arrivent

                          Deal Size : $1,207.0 million

                          Deal Type : Licensing Agreement

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                          06

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Under the licensing agreement, Sotio's SOT109 will leverage antibodies generated with Biocytogen RenMab platform as the backbone of ADC for colorectal cancer and other gastrointestinal cancers.

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          January 09, 2025

                          Lead Product(s) : SOT109

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Sotio

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          07

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Through the collaboration, Zai Lab further expands its oncology pipeline with another potential first-in-class, ADC ZL-6201 targeting multiple solid tumors.

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          January 09, 2025

                          Lead Product(s) : ZL-6201

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : MediLink Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          08

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Under the license agreement, Aadi is granted exclusive rights to three preclinical ADC programs, including PTK7-CPT113, which is being evaluated for the treatment of NSCLC.

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : $44.0 million

                          December 19, 2024

                          Lead Product(s) : PTK7-CPT113

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Aadi Bioscience

                          Deal Size : $849.0 million

                          Deal Type : Licensing Agreement

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                          09

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Under the terms of the agreement, Biocytogen will use cutting-edge platforms for antibody discovery to support Adcendo’s innovative ADC drug development for cancer.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          December 16, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Adcendo

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          10

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : GSK gains an exclusive option to obtain a license to develop and commercialize a potentially best-in-class ADC candidate, DB-1324 worldwide (excluding mainland China, Hong Kong, and Macau).

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : $30.0 million

                          December 04, 2024

                          Lead Product(s) : DB-1324

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : GSK

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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