
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : NVG-222
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Mabion SA
Deal Size : Undisclosed
Deal Type : Partnership
Mabion, NovalGen Partner to Bring NVG-222 to Market
Details : The partnership aims to bring the proprietary T-cell engager, NVG-222 targeting ROR1 and CD3, to market for phase one of in-human clinical trials.
Product Name : NVG-222
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
June 30, 2025
Lead Product(s) : NVG-222
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Mabion SA
Deal Size : Undisclosed
Deal Type : Partnership

Details : NVG-111 is generally well tolerated with a predictable and manageable safety profile. Promising evidence of efficacy was observed which appears to be durable in two subjects with MRD4 negative CR.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 03, 2022

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Lead Product(s) : NVG-111
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
NovalGen announces compelling data from the Phase 1/2 Study of NVG-111 at the ASCO Annual Meeting
Details : NVG-111 was well tolerated with the most common adverse event being transient, Grade 1 lethargy, headaches, nausea, vomiting and thrombocytopenia. Dose escalation is ongoing, including exploration of step-up dosing.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
May 26, 2022
Lead Product(s) : NVG-111
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : NVG-111
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NVG-111 is a first in class bispecific antibody T cell engager targeting receptor tyrosine kinase-like orphan receptor 1 (ROR1).
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
May 20, 2021
Lead Product(s) : NVG-111
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Noval Gen Enters Strategic Partnership with Halix B.V. to Manufacture Clinical Trial Materials
Details : HALIX will provide manufacturing and clinical supply of NovalGen's therapies as part of this partnership. HALIX has supported NovalGen with the successful completion of GMP manufacture of NVG-111 from drug substance up to drug product and final release.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
February 22, 2021

First in Human Study of NVG-111 in Relapsed/Refractory ROR1+ Malignancies
Details : NVG-111 is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Leukemia, Lymphocytic, Chronic, B-Cell.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
February 21, 2021
