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II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Solution","sponsorNew":"IGC Pharma \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"IGC Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Addex Therapeutics","sponsor":"Johnson & Johnson","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"SWITZERLAND","productType":"Other Small Molecule","year":"2025","type":"Termination","leadProduct":"ADX71149","moa":"mGlu2 receptor","graph1":"Neurology","graph2":"Phase II","graph3":"Addex Therapeutics","amount2":0.13,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0.13,"dosageForm":"Oral Capsule","sponsorNew":"Addex Therapeutics \/ Johnson & Johnson","highestDevelopmentStatusID":"8","companyTruncated":"Addex Therapeutics \/ Johnson & Johnson"},{"orgOrder":0,"company":"H. 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                            Sanofi

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                            Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

                            Lead Product(s) : Frexalimab

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

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                            Positive Phase 2 Data of Novel Investigational Anti-CD40L Antibody Frexalimab Show Significantly Reduced Disea...

                            Details : SAR441344 (frexalimab) is a novel monoclonal antibody that is thought to block the costimulatory CD40/CD40L and investigational product relapsing multiple sclerosis.

                            Product Name : SAR441344

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            May 31, 2023

                            Lead Product(s) : Frexalimab

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

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                            Evonik

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                            Virtual BoothEvonik's CDMO solutions for APIs and HPAPIs: It specializes where the client needs it most!

                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Allay Therapeutics

                            Deal Size : Inapplicable

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                            No Opioids After Surgery: Evonik Invests in Allay Therapeutics and Supplies Key Technology for Pain Therapy Im...

                            Details : ATX-101 is a small product placed directly into the TKA surgical site in a simple, ‘place & go’ manner designed to add minimal extra complexity and time to the procedure.

                            Product Name : ATX-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 13, 2022

                            Lead Product(s) : Bupivacaine

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Allay Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Pfizer CentreOne

                            U.S.A
                            APGA Annual Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothPfizer CentreOne is a global CDMO and a leading supplier of Specialty APIs.

                            Lead Product(s) : Squalamine phosphate

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Enterin

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            How Creative Chemistry and Collaboration Synthesized a Better Drug Strategy For Enterin

                            Details : Enterin completed the first human clinical trials for ENT-01 which demonstrated that oral administration of its treatment has restored function of the nervous system of the gastrointestinal tract in Parkinson’s patients.

                            Product Name : ENT-01

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 28, 2022

                            Lead Product(s) : Squalamine phosphate

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Enterin

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            04

                            Dr. Reddy's Laboratories

                            India
                            CPhI Korea
                            Attending
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : MediCane Health

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Dr. Reddy's Laboratories and MediCane Health Announce the Launch of Medical Cannabis Products in Germany

                            Details : As part of a collaboration between Dr. Reddy's and MediCane that started in 2021, MediCane will supply the medical cannabis products to Dr. Reddy's from its EU-GMP-certified facilities in Portugal along with providing logistical and regulatory support.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            January 04, 2022

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : MediCane Health

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            05

                            Sanofi

                            France
                            ChemOutsourcing
                            Attending
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

                            Lead Product(s) : Tolebrutinib

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            New Long-Term Data Reinforcing Promising Safety and Efficacy Profile of Brain-Penetrant Tolebrutinib Presented...

                            Details : Tolebrutinib is an investigational brain-penetrant Bruton’s tyrosine kinase inhibitor that achieves CSF concentrations needed for targeting B lymphocytes and microglial cells, modulating neuroinflammation.

                            Product Name : SAR442168

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 13, 2021

                            Lead Product(s) : Tolebrutinib

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Evonik

                            Germany
                            CPhI WW Frankfurt
                            Booth #6.1B44
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothEvonik's CDMO solutions for APIs and HPAPIs: It specializes where the client needs it most!

                            Lead Product(s) : Simufilam

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Cassava Sciences

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Evonik and Cassava Sciences Join Forces to Fight Alzheimer’s Disease

                            Details : Evonik to supply commercial quantities of simufilam, a drug candidate for the treatment of Alzheimer’s disease. Simufilam is a novel drug, discovered at Cassava Sciences, that targets both neuroinflammation and neurodegeneration.

                            Product Name : PTI-125

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            September 03, 2021

                            Lead Product(s) : Simufilam

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Cassava Sciences

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            07

                            Sanofi

                            France
                            ChemOutsourcing
                            Attending
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

                            Lead Product(s) : Tolebrutinib

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sanofi brain-penetrant BTK inhibitor meets primary endpoint

                            Details : Sanofi’s BTK inhibitor will be first disease-modifying therapy to address sources of multiple sclerosis damage in the brain.

                            Product Name : SAR442168

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 02, 2020

                            Lead Product(s) : Tolebrutinib

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Sanofi

                            France
                            ChemOutsourcing
                            Attending
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

                            Lead Product(s) : Tolebrutinib

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sanofi to Present Phase 2 Detailed Results of its Brain-Penetrant BTK Inhibitor in Relapsing Multiple Sclerosi...

                            Details : Study’s primary endpoint was met, demonstrating that the BTK inhibitor significantly reduced disease activity associated with multiple sclerosis (MS) as measured by magnetic resonance imaging.

                            Product Name : SAR442168

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 17, 2020

                            Lead Product(s) : Tolebrutinib

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Novaremed

                            Switzerland arrow
                            APGA Annual Conference
                            Not Confirmed

                            Novaremed

                            Switzerland arrow
                            APGA Annual Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : NRD135s.E1

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Novaremed Completes Enrollment in Phase 2b Chronic Pain Drug Trial

                            Details : NRD.E1 (or NRD135S.E1), an orally active small molecule with a novel mechanism of action, is being developed to treat chronic pain associated with diabetic peripheral neuropathy.

                            Product Name : NRD.E1

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 06, 2025

                            Lead Product(s) : NRD135s.E1

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Beijing Tide Pharmaceutical

                            China arrow
                            APGA Annual Conference
                            Not Confirmed

                            Beijing Tide Pharmaceutical

                            China arrow
                            APGA Annual Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : TRD205

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            TRD205 AT2R Antagonist Enters Phase 2 Pain Trial with First Patient Dosed

                            Details : TRD205 is a highly selective angiotensin II type 2 receptor (AT2R) antagonist. It is being evaluated for the treatment of chronic post-surgical neuropathic pain trial.

                            Product Name : TRD205

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 05, 2025

                            Lead Product(s) : TRD205

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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