[{"orgOrder":0,"company":"Argenx","sponsor":"Zai Lab","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"NETHERLANDS","productType":"Antibody, Unconjugated","year":"2023","type":"Inapplicable","leadProduct":"Efgartigimod","moa":"IgG receptor FcRn large subunit p51","graph1":"Nephrology","graph2":"Phase II","graph3":"Argenx","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Argenx \/ Zai Lab","highestDevelopmentStatusID":"8","companyTruncated":"Argenx \/ Zai Lab"},{"orgOrder":0,"company":"Argenx","sponsor":"Zai Lab","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"NETHERLANDS","productType":"Antibody, Unconjugated","year":"2023","type":"Inapplicable","leadProduct":"Efgartigimod","moa":"IgG receptor FcRn large subunit p51","graph1":"Nephrology","graph2":"Phase II","graph3":"Argenx","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Argenx \/ Zai Lab","highestDevelopmentStatusID":"8","companyTruncated":"Argenx \/ Zai Lab"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : recAP (Ilofotase Alfa), a recombinant alkaline phosphatase, is in Phase 2 trials for cardiac surgery-associated renal damage.

                          Product Name : recAP

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          January 16, 2024

                          Lead Product(s) : Ilofotase Alpha

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Efgartigimod is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Lupus Nephritis.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          April 13, 2023

                          Lead Product(s) : Efgartigimod

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Zai Lab

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Efgartigimod is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Glomerulonephritis, Membranous.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          April 13, 2023

                          Lead Product(s) : Efgartigimod

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Zai Lab

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : New capital to be used to support a multi-national pivotal Phase III trial of recAP in 1,400 patients with sepsis-associated-acute kidney injury (SA-AKI).

                          Product Name : recAP

                          Product Type : Enzyme

                          Upfront Cash : Undisclosed

                          March 31, 2020

                          Lead Product(s) : Ilofotase Alpha

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Cowen

                          Deal Size : $176.0 million

                          Deal Type : Funding

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