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    [{"orgOrder":0,"company":"Lion TCR","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SINGAPORE","productType":"Cell & Gene Therapy","year":"2018","type":"Inapplicable","leadProduct":"Autologous Hbv-Tcr T Cell Therapy","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Lion TCR \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Lion TCR \/ Undisclosed"},{"orgOrder":0,"company":"Lion TCR","sponsor":"Beijing GoBroad Hospital","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SINGAPORE","productType":"Cell & Gene Therapy","year":"2025","type":"Inapplicable","leadProduct":"Autologous Hbv-Tcr T Cell Therapy","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Lion TCR \/ Beijing GoBroad Hospital","highestDevelopmentStatusID":"7","companyTruncated":"Lion TCR \/ Beijing GoBroad Hospital"},{"orgOrder":0,"company":"Lion TCR","sponsor":"Lion TCR","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CHINA","productType":"Protein","year":"2025","type":"Inapplicable","leadProduct":"Liocyx-M","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Lion TCR \/ Lion TCR","highestDevelopmentStatusID":"6","companyTruncated":"Lion TCR \/ Lion TCR"},{"orgOrder":0,"company":"Lion TCR","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SINGAPORE","productType":"Protein","year":"2022","type":"Inapplicable","leadProduct":"Liocyx-M","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase II","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lion TCR \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Lion TCR \/ Undisclosed"},{"orgOrder":0,"company":"Lion TCR","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SINGAPORE","productType":"Cell & Gene Therapy","year":"2021","type":"Inapplicable","leadProduct":"LioCyx-M004","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"Lion TCR \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Lion TCR \/ Undisclosed"},{"orgOrder":0,"company":"Lion TCR","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SINGAPORE","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"mRNA Modified HBV-TCR Redirected T-Cell","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Lion TCR \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Lion TCR \/ Undisclosed"},{"orgOrder":0,"company":"Lion TCR","sponsor":"Lion TCR","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Cell & Gene Therapy","year":"2019","type":"Inapplicable","leadProduct":"TCR-T Cell","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Lion TCR \/ Lion TCR","highestDevelopmentStatusID":"6","companyTruncated":"Lion TCR \/ Lion TCR"},{"orgOrder":0,"company":"Lion TCR","sponsor":"First Affiliated Hospital, Sun Yat-Sen University | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SINGAPORE","productType":"Cell & Gene Therapy","year":"2016","type":"Inapplicable","leadProduct":"TCR-T Cell","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lion TCR \/ First Affiliated Hospital, Sun Yat-Sen University | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","highestDevelopmentStatusID":"6","companyTruncated":"Lion TCR \/ First Affiliated Hospital, Sun Yat-Sen University | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University"},{"orgOrder":0,"company":"Lion TCR","sponsor":"A*STAR | Third Affiliated Hospital, Sun Yat-sen University","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SINGAPORE","productType":"Cell & Gene Therapy","year":"2016","type":"Inapplicable","leadProduct":"TCR-T Cell","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lion TCR \/ A*STAR | Third Affiliated Hospital, Sun Yat-sen University","highestDevelopmentStatusID":"6","companyTruncated":"Lion TCR \/ A*STAR | Third Affiliated Hospital, Sun Yat-sen University"},{"orgOrder":0,"company":"Lion TCR","sponsor":"Zelluna Immunotherapy","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"NORWAY","productType":"Undisclosed","year":"2020","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Undisclosed","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lion TCR \/ Lion TCR","highestDevelopmentStatusID":"1","companyTruncated":"Lion TCR \/ Lion TCR"},{"orgOrder":0,"company":"Lion TCR","sponsor":"MaxCyte","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lion TCR \/ Lion TCR","highestDevelopmentStatusID":"4","companyTruncated":"Lion TCR \/ Lion TCR"},{"orgOrder":0,"company":"Lion TCR","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"SINGAPORE","productType":"Cell & Gene Therapy","year":"2025","type":"Inapplicable","leadProduct":"LioCyx-M004","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"IND Enabling","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lion TCR \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"Lion TCR \/ Undisclosed"},{"orgOrder":0,"company":"Lion TCR","sponsor":"Xiaoshun He","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SINGAPORE","productType":"Cell & Gene Therapy","year":"2020","type":"Inapplicable","leadProduct":"TCR-T Cell","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Lion TCR","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Lion TCR \/ Xiaoshun He","highestDevelopmentStatusID":"6","companyTruncated":"Lion TCR \/ Xiaoshun He"}]

    Find Clinical Drug Pipeline Developments & Deals by Lion TCR

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                            01

                            Lion TCR

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                            Lead Product(s) : LioCyx-M004

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Lion TCR Gets IND Clearance for Chronic Hepatitis B After Fast Track, Orphan Status

                            Details : LioCyx-M004 represents an innovative autologous cell therapy engineered using mRNA to encode T-cell receptors that specifically target hepatitis B virus antigens.

                            Product Name : LioCyx-M004

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            September 15, 2025

                            Lead Product(s) : LioCyx-M004

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Lion TCR

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                            Lion TCR

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                            Lead Product(s) : Autologous Hbv-Tcr T Cell Therapy

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Beijing GoBroad Hospital

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Autologous HBV-TCR T Cell Therapy (LioCyx-M) for the Treatment of Hepatocellular Carcinoma

                            Details : LioCyx-M (Autologous Hbv-Tcr T Cell Therapy) is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Carcinoma, Hepatocellular.

                            Product Name : LioCyx-M

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            May 08, 2025

                            Lead Product(s) : Autologous Hbv-Tcr T Cell Therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Beijing GoBroad Hospital

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Lion TCR

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                            Lead Product(s) : Liocyx-M

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Recipient : Changhai Hospital

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            HBV-Specific TCR-T Cell Therapy Combined With Nucleos(t)Ide Analogues in Chronic Hepatitis B Patients

                            Details : Liocyx-M is a Protein drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hepatitis B, Chronic.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            March 20, 2025

                            Lead Product(s) : Liocyx-M

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Recipient : Changhai Hospital

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Lion TCR

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery Platform

                            Recipient : MaxCyte

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            MaxCyte and Lion TCR Partner To Expand TCR-T Cell Pipeline Globally

                            Details : Under the agreement, Lion TCR obtains worldwide non-exclusive rights to use MaxCyte’s Flow Electroporation® technology and ExPERT™ platform for developing new TCR-T cell therapies for solid tumors.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            January 03, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery Platform

                            Recipient : MaxCyte

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            05

                            Lion TCR

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                            Lead Product(s) : Liocyx-M

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of HBV-TCR T Cells (LioCyx-M) as Monotherapy or as Combination With Lenvatinib for HBV-related HCC

                            Details : Liocyx-M is a Protein drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Carcinoma, Hepatocellular.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            January 18, 2022

                            Lead Product(s) : Liocyx-M

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Lion TCR

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                            Lead Product(s) : LioCyx-M004

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Lion TCR Receives FDA Fast Track Designation for its HBV-specific TCR T Cell Therapy for Hepatocellular Carcin...

                            Details : This designation was granted based on the efficacy of LioCyx-M004, an autologous T-cells transfected with mRNA encoding HBsAg, as demonstrated by an improvement in the overall survival in patients with HBsAg-positive HCC relapsed or refractory to prior s...

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            December 23, 2021

                            Lead Product(s) : LioCyx-M004

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Lion TCR

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                            Lion TCR

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                            Lead Product(s) : mRNA Modified HBV-TCR Redirected T-Cell

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Redirected HBV-Specific T Cells in Patients With HBV-related HCC (SAFE-T-HBV)

                            Details : MRNA Modified HBV-TCR Redirected T-Cell is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Carcinoma, Hepatocellular.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            February 09, 2021

                            Lead Product(s) : mRNA Modified HBV-TCR Redirected T-Cell

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Lion TCR

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                            Lion TCR

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                            Lead Product(s) : TCR-T Cell

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Xiaoshun He

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            TCR-Redirected T Cell Treatment in Patients With Recurrent HBV-related Hepatocellular Carcinoma Post Liver Tra...

                            Details : TCR-T Cell is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Carcinoma, Hepatocellular.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            December 21, 2020

                            Lead Product(s) : TCR-T Cell

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Xiaoshun He

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Lion TCR

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                            Lion TCR

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Undisclosed

                            Recipient : Zelluna Immunotherapy

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Zelluna Collaborates with Lion TCR to Develop TCR-NK Cell Therapies to Treat Virally Induced Cancers

                            Details : The collaboration will initially focus on the development of TCR-NK products targeting Hepatitis B Virus (HBV) which is a leading cause of liver cancer and has a high unmet need for efficient treatment options.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            June 24, 2020

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Undisclosed

                            Recipient : Zelluna Immunotherapy

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            10

                            Lion TCR

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                            Lead Product(s) : TCR-T Cell

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Beijing 302 Hospital

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            TCR-Redirected T Cells Therapy in Patient With HBV Related HCC

                            Details : TCR-T Cell is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Carcinoma, Hepatocellular.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            April 02, 2019

                            Lead Product(s) : TCR-T Cell

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Beijing 302 Hospital

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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