Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : LioCyx-M004
Therapeutic Area : Infections and Infectious Diseases
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lion TCR Gets IND Clearance for Chronic Hepatitis B After Fast Track, Orphan Status
Details : LioCyx-M004 represents an innovative autologous cell therapy engineered using mRNA to encode T-cell receptors that specifically target hepatitis B virus antigens.
Product Name : LioCyx-M004
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
September 15, 2025
Lead Product(s) : LioCyx-M004
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Autologous HBV-TCR T Cell Therapy (LioCyx-M) for the Treatment of Hepatocellular Carcinoma
Details : LioCyx-M (Autologous Hbv-Tcr T Cell Therapy) is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Carcinoma, Hepatocellular.
Product Name : LioCyx-M
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
May 08, 2025
Lead Product(s) : Liocyx-M
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Recipient : Changhai Hospital
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Liocyx-M is a Protein drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hepatitis B, Chronic.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
March 20, 2025
Lead Product(s) : Liocyx-M
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Recipient : Changhai Hospital
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Recipient : MaxCyte
Deal Size : Undisclosed
Deal Type : Licensing Agreement
MaxCyte and Lion TCR Partner To Expand TCR-T Cell Pipeline Globally
Details : Under the agreement, Lion TCR obtains worldwide non-exclusive rights to use MaxCyte’s Flow Electroporation® technology and ExPERT™ platform for developing new TCR-T cell therapies for solid tumors.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
January 03, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Recipient : MaxCyte
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Liocyx-M is a Protein drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Carcinoma, Hepatocellular.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
January 18, 2022
Lead Product(s) : LioCyx-M004
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : This designation was granted based on the efficacy of LioCyx-M004, an autologous T-cells transfected with mRNA encoding HBsAg, as demonstrated by an improvement in the overall survival in patients with HBsAg-positive HCC relapsed or refractory to prior s...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
December 23, 2021
Lead Product(s) : LioCyx-M004
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Redirected HBV-Specific T Cells in Patients With HBV-related HCC (SAFE-T-HBV)
Details : MRNA Modified HBV-TCR Redirected T-Cell is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Carcinoma, Hepatocellular.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
February 09, 2021
Details : TCR-T Cell is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Carcinoma, Hepatocellular.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
December 21, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Undisclosed
Recipient : Zelluna Immunotherapy
Deal Size : Undisclosed
Deal Type : Collaboration
Zelluna Collaborates with Lion TCR to Develop TCR-NK Cell Therapies to Treat Virally Induced Cancers
Details : The collaboration will initially focus on the development of TCR-NK products targeting Hepatitis B Virus (HBV) which is a leading cause of liver cancer and has a high unmet need for efficient treatment options.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
June 24, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Recipient : Zelluna Immunotherapy
Deal Size : Undisclosed
Deal Type : Collaboration