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therapy","year":"2025","type":"Funding","leadProduct":"AGENT-797","moa":"Undisclosed","graph1":"Immunology","graph2":"Phase I","graph3":"MiNK Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"MiNK Therapeutics \/ National Institute of Allergy and Infectious Diseases","highestDevelopmentStatusID":"6","companyTruncated":"MiNK Therapeutics \/ National Institute of Allergy and Infectious Diseases"},{"orgOrder":0,"company":"ImmunAbs","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SOUTH KOREA","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"IM-101","moa":"C5 receptor","graph1":"Immunology","graph2":"Phase I","graph3":"ImmunAbs","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"ImmunAbs \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"ImmunAbs \/ Inapplicable"},{"orgOrder":0,"company":"Capstan Therapeutics","sponsor":"AbbVie Inc","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Acquisition","leadProduct":"CPTX2309","moa":"CD19","graph1":"Immunology","graph2":"Phase I","graph3":"Capstan Therapeutics","amount2":2.1000000000000001,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":2.1000000000000001,"dosageForm":"Undisclosed","sponsorNew":"Capstan Therapeutics \/ Abbvie Inc","highestDevelopmentStatusID":"6","companyTruncated":"Capstan Therapeutics \/ Abbvie Inc"}]

    Find Immunology Drugs in Phase I Clinical Development in UNITED STATES

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                            01

                            Dr. Reddy's Laboratories

                            India
                            CPhI Korea
                            Attending
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

                            Lead Product(s) : Tocilizumab

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Dr. Reddy’s Successfully Completes Phase I Study (IV Route) of DRL_TC, a Proposed Biosimilar of Tocilizumab

                            Details : Tocilizumab Biosimilar is a recombinant humanized monoclonal antibody targeting IL-6R, which specifically binds to sIL-6R and mIL-6R and inhibits signaling mediated by sIL-6R or mIL-6R. It is approved for the treatment of RA, sJIA, and CRS.

                            Product Name : DRL_TC

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            May 06, 2023

                            Lead Product(s) : Tocilizumab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Dr. Reddy's Laboratories

                            India
                            CPhI Korea
                            Attending
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

                            Lead Product(s) : Tocilizumab

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Dr. Reddy’s Successfully Completes Phase 1 Study Of DRL_TC, a Proposed Biosimilar of Tocilizumab

                            Details : Tocilizumab is an important anti-rheumatic agent used in the treatment of adult patients with moderate to severe active rheumatoid arthritis who have had an inadequate response to one or more Disease-Modifying Anti-Rheumatic Drugs (DMARDs).

                            Product Name : DRL_TC

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            December 19, 2022

                            Lead Product(s) : Tocilizumab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Capstan Therapeutics

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Capstan Therapeutics

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : CPTX2309

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : AbbVie Inc

                            Deal Size : $2,100.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            AbbVie to Acquire Capstan, Further Strengthening in Immunology

                            Details : Through the acqusition, Abbvie will leverage Capstan pipeline, including CPTX2309, anti-CD19 CAR-T therapy candidate, currently in Phase 1, in development for the treatment of autoimmune diseases.

                            Product Name : CPTX2309

                            Product Type : Cell and Gene therapy

                            Upfront Cash : $2,100.0 million

                            June 30, 2025

                            Lead Product(s) : CPTX2309

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : AbbVie Inc

                            Deal Size : $2,100.0 million

                            Deal Type : Acquisition

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                            04

                            MiNK Therapeutics

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            MiNK Therapeutics

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : AGENT-797

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : National Institute of Allergy and Infectious Diseases

                            Deal Size : Undisclosed

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            MiNK Awarded Prestigious NIAID Grant to Advance Allo-iNKT Cell Therapy

                            Details : The grant will support development of MiNK’s allo-iNKT cell therapy, AGENT-797, for the prevention and treatment of graft-versus-host disease (GvHD) following hematopoietic stem cell transplantation.

                            Product Name : AGENT-797

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            June 02, 2025

                            Lead Product(s) : AGENT-797

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : National Institute of Allergy and Infectious Diseases

                            Deal Size : Undisclosed

                            Deal Type : Funding

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                            05

                            ImmunAbs

                            South Korea arrow
                            Discovery Europe
                            Not Confirmed

                            ImmunAbs

                            South Korea arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : IM-101

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ImmunAbs Announces FDA Phase 2 IND Approval of IM-101 for Treatment of Myasthenia Gravis

                            Details : IM-101 is a humanized monoclonal antibody targeting complement C5 with high affinity. Ci=urrently being investigated for treating myasthenia gravis.

                            Product Name : IM-101

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            June 02, 2025

                            Lead Product(s) : IM-101

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Dren Bio

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Dren Bio

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : SAR448501

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Sanofi

                            Deal Size : $1,900.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Sanofi Completes Acquisition of DR-0201

                            Details : Sanofi acquired DR-0201, now named SAR448501, a targeted bispecific myeloid cell engager, has shown robust B-cell depletion in pre-clinical and early clinical studies.

                            Product Name : DR-0201

                            Product Type : Antibody

                            Upfront Cash : $600.0 million

                            May 27, 2025

                            Lead Product(s) : SAR448501

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Sanofi

                            Deal Size : $1,900.0 million

                            Deal Type : Acquisition

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                            07

                            Innovo Therapeutics

                            South Korea arrow
                            Discovery Europe
                            Not Confirmed

                            Innovo Therapeutics

                            South Korea arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : INV-101

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Innovo Reports Positive Phase 1 for INV-101 Targeting Autoimmune Diseases

                            Details : INV-101, a novel oral immuno-metabolic modulator targeting glycogen phosphorylase. It is being evaluated for the treatment of autoimmune diseases.

                            Product Name : INV-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 12, 2025

                            Lead Product(s) : INV-101

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Seismic Therapeutic

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Seismic Therapeutic

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : S-4321

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Seismic Doses First Patients with S-4321 PD-1/FcγRIIb Autoimmune Drug

                            Details : S-4321 is a novel bifunctional antibody that agonizes PD-1 and FcγRIIb inhibitory receptors for the treatment of autoimmune disease.

                            Product Name : S-4321

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            April 10, 2025

                            Lead Product(s) : S-4321

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Tr1X Bio

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Tr1X Bio

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : TRX103

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : California Institute for Regenerative Medicine

                            Deal Size : $8.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Tr1x Awarded $8 Million Cirm Grant for TRX103 Phase 1/2a Clinical Trial

                            Details : The funding aims to advance the development of TRX103 an engineered Tr1 Treg cell therapy for use in the prevention of GvHD in blood cancer patients undergoing mismatched stem cell transplants.

                            Product Name : TRX103

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            April 04, 2025

                            Lead Product(s) : TRX103

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : California Institute for Regenerative Medicine

                            Deal Size : $8.0 million

                            Deal Type : Funding

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                            10

                            Allakos

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Allakos

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : AK006

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Concentra Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Allakos to Be Acquired By Concentra Biosciences for $0.33 Per Share

                            Details : Through the acquisition, Company will be developing therapeutics that target immunomodulatory receptors, including AK006, a humanized IgG1 monoclonal antibody.

                            Product Name : AK006

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            April 02, 2025

                            Lead Product(s) : AK006

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Concentra Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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