[{"orgOrder":0,"company":"Escape Bio","sponsor":"Wellington Management Company","pharmaFlowCategory":"D","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Financing","leadProduct":"ESB1609","moa":"S1P5 receptor","graph1":"Rare Diseases and Disorders","graph2":"Phase I","graph3":"Escape Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"Escape Bio \/ Wellington Management Company","highestDevelopmentStatusID":"6","companyTruncated":"Escape Bio \/ Wellington Management Company"},{"orgOrder":0,"company":"Escape Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"ESB1609","moa":"S1P5 receptor","graph1":"Rare Diseases and Disorders","graph2":"Phase I","graph3":"Escape Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Escape Bio \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Escape Bio \/ Inapplicable"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          APS Symposium
                          Not Confirmed
                          APS Symposium
                          Not Confirmed

                          Details : ESCAPE Bio is developing novel, precisely targeted therapeutics for genetically defined neurodegenerative diseases. ESB1609 is in a Phase 1 multiple ascending dose study in healthy volunteers.

                          Product Name : ESB1609

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          September 14, 2020

                          Lead Product(s) : ESB1609

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I

                          Sponsor : Wellington Management Company

                          Deal Size : $73.0 million

                          Deal Type : Financing

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                          02

                          APS Symposium
                          Not Confirmed
                          APS Symposium
                          Not Confirmed

                          Details : ESB1609 demonstrated durable CSF pharmacokinetics and excellent safety & tolerability in a single ascending dose Phase 1 Study.

                          Product Name : ESB1609

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 01, 2020

                          Lead Product(s) : ESB1609

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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