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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Olumiant (baricitinib) is an oral JAK1/JAK2 inhibitor, small molecule drug candidate, which is being evaluated for the treatment of severe alopecia areata.

                          Product Name : Olumiant

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 08, 2025

                          Lead Product(s) : Baricitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Ebglyss (lebrikizumab) is an approved high-affinity and potent IL-13 inhibitor being studied in adult and adolescent patients 12 years of age and older with moderate-to-severe AD.

                          Product Name : LY3650150

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          October 03, 2024

                          Lead Product(s) : Lebrikizumab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Ebglyss (lebrikizumab) is an approved high-affinity and potent IL-13 inhibitor approved for patients 12 years or older with moderate-to-severe Atopic Dermatitis.

                          Product Name : LY3650150

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          September 13, 2024

                          Lead Product(s) : Lebrikizumab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Through the acquisition, Lilly expand its immunology pipeline by including, DICE therapeutics' oral IL-17 inhibitors, DC-806 and DC-853. DC-806 is an oral small molecule and a validated drug target for the treatment of autoimmune and inflammatory disease...

                          Product Name : DC-806

                          Product Type : Other Small Molecule

                          Upfront Cash : $2,400.0 million

                          September 08, 2023

                          Lead Product(s) : DC-806

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Eli Lilly

                          Deal Size : $2,400.0 million

                          Deal Type : Acquisition

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                          05

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Through the acquisition, Lilly expand its immunology pipeline by including, DICE therapeutics' oral IL-17 inhibitors, DC-806 and DC-853. DC-806 is an oral small molecule and a validated drug target for the treatment of autoimmune and inflammatory disease...

                          Product Name : DC-806

                          Product Type : Other Small Molecule

                          Upfront Cash : $2,400.0 million

                          June 20, 2023

                          Lead Product(s) : DC-806

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Eli Lilly

                          Deal Size : $2,400.0 million

                          Deal Type : Acquisition

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                          06

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Copellor (ixekizumab) is a human IgG mAb that selectively binds to IL-17A and prevents IL-17A binding to IL-17 receptor. Thus, this attenuates an inflammatory response mediated by interleukin 17A. It is indicated treat moderate-to-severe plaque psoriasis...

                          Product Name : Taltz

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          March 14, 2023

                          Lead Product(s) : Ixekizumab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Ebglyss (lebrikizumab) is an investigational, monoclonal antibody that binds IL-13, and FDA has issued a complete response letter for the lebrikizumab biologic license application (BLA) for the treatment of moderate-to-severe atopic dermatitis (eczema).

                          Product Name : LY3650150

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          February 10, 2023

                          Lead Product(s) : Lebrikizumab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : LY3650150 (lebrikizumab) is an investigational high-affinity and potent IL-13 inhibitor being studied in adult and adolescent patients 12 years of age and older with moderate-to-severe AD.

                          Product Name : LY3650150

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          January 05, 2023

                          Lead Product(s) : Lebrikizumab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Company expects to use the net proceeds from the offering, for general corporate purposes and working capital, including the development of its drug product candidates including DC-806.

                          Product Name : DC-806

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 10, 2022

                          Lead Product(s) : DC-806

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase I

                          Sponsor : BofA Securities

                          Deal Size : $300.0 million

                          Deal Type : Public Offering

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                          10

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : DC-806 is well tolerated with an excellent safety profile across all dose groups in healthy volunteers and psoriasis patients with a robust PK profile and clear pharmacodynamic effects on two distinct biomarkers at both high and low doses of DC-806.

                          Product Name : DC-806

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 10, 2022

                          Lead Product(s) : DC-806

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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