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Chemistry

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Also known as: 1383982-64-6, Azd-3293, Ly3314814, Azd3293, Lanabecestat [usan], X8spj492vf
Molecular Formula
C26H28N4O
Molecular Weight
412.5  g/mol
InChI Key
WKDNQONLGXOZRG-BOPKNSRXSA-N
FDA UNII
X8SPJ492VF

Lanabecestat
Lanabecestat is under investigation in clinical trial NCT03499041 (A Study of LY3314814 in Participants With Liver Impairment).
1 2D Structure

Lanabecestat

2 Identification
2.1 Computed Descriptors
2.1.1 InChI
InChI=1S/C26H28N4O/c1-4-5-18-12-21(16-28-15-18)19-6-7-20-14-25(10-8-22(31-3)9-11-25)26(23(20)13-19)29-17(2)24(27)30-26/h6-7,12-13,15-16,22H,8-11,14H2,1-3H3,(H2,27,30)/t22?,25?,26-/m0/s1
2.1.2 InChI Key
WKDNQONLGXOZRG-BOPKNSRXSA-N
2.1.3 Canonical SMILES
CC#CC1=CC(=CN=C1)C2=CC3=C(CC4(C35N=C(C(=N5)N)C)CCC(CC4)OC)C=C2
2.1.4 Isomeric SMILES
CC#CC1=CC(=CN=C1)C2=CC3=C(CC4([C@]35N=C(C(=N5)N)C)CCC(CC4)OC)C=C2
2.2 Other Identifiers
2.2.1 UNII
X8SPJ492VF
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-methoxy-5'-methyl-6'-(5-(prop-1-yn-1-yl)pyridin-3-yl)-3'h-dispiro(cyclohexane-1,2'-inden-1',2'-imidazol)-4'-amine

2. Azd3293

2.3.2 Depositor-Supplied Synonyms

1. 1383982-64-6

2. Azd-3293

3. Ly3314814

4. Azd3293

5. Lanabecestat [usan]

6. X8spj492vf

7. Lanabecestat (azd3293; Ly3314814)

8. Chembl4217620

9. Ly-3314814

10. Lanabecestat (usan)

11. (1,4-trans,1'r)-4-methoxy-5''-methyl-6'-(5-(prop-1-yn-1-yl)pyridin-3-yl)-3'h-dispiro(cyclohexane-1,2'-indene-1',2''-imidazol)-4''-amine

12. (1r,1'r,4r)-4-methoxy-5''-methyl-6'-(5-(prop-1-yn-1-yl)pyridin-3-yl)-3'h-- Dispiro(cyclohexane-1,2'-indene-1',2''-imidazol)-4''-amine

13. (1r,1'r,4r)-4-methoxy-5''-methyl-6'-(5-(prop-1-yn-1-yl)pyridin-3-yl)-3'h-dispiro[cyclohexane-1,2'-indene-1',2''-imidazol]-4''-amine

14. Dispiro[cyclohexane-1,2'-[2h]indene-1'(3'h),2''-[2h]imidazol]-4''-amine, 4-methoxy-5''-methyl-6'-[5-(1-propyn-1-yl)-3-pyridinyl]-, (1alpha,1'r,4beta)-

15. Dispiro(cyclohexane-1,2'-(2h)indene-1'(3'h),2''-(2h)imidazol)-4''-amine, 4-methoxy-5''-methyl-6'-(5-(1-propyn-1-yl)-3-pyridinyl)-, (1alpha,1'r,4beta)-

16. Lanabecestat [inn]

17. Unii-x8spj492vf

18. Lanabecestat [who-dd]

19. Gtpl7789

20. Schembl9947926

21. Schembl9947930

22. Chembl3261045

23. Chembl3349234

24. Chembl3989948

25. Schembl10249890

26. Schembl20702043

27. Schembl23085139

28. Bdbm41537

29. Bdbm41542

30. Bdbm136733

31. Hms3886b08

32. Azd 3293

33. Bcp16986

34. Ex-a1471

35. Bdbm50012629

36. Bdbm50452874

37. S8193

38. Zinc95576075

39. Us8865911, 20a Isomer 1

40. Ccg-268796

41. Cs-7494

42. Db14814

43. Sb18857

44. Ac-33090

45. Lanabecestat(azd3293,ly-3314814)

46. Hy-100740

47. Ly 3314814

48. D10946

49. Us8865911, 114

50. Us8865911, 122

51. Q27293694

52. Azd-3293;azd 3293;ly-3314814;ly 3314814;ly3314814

53. (1r,1'r,4r)-4-methoxy-5''-methyl-6'-(5-(prop-1-yn-1-yl)pyridin-3-yl)-3'h-dispiro(cyclohexane-1,2'-inden-1',2''-imidazol)-4''-amine

54. (1r,4r)-4-methoxy-5''-methyl-6'-(5-(prop-1-yn-1-yl)pyridin-3-yl)-3'h-dispiro[cyclohexane-1,2'-indene-1',2''-imidazol]-4''-amine

55. 1383984-21-1

56. 4-methoxy-5'-methyl-6'-(5-(prop-1-yn-1-yl)pyridin-3-yl)-3'h-dispiro(cyclohexane-1,2'-inden-1',2'-imidazol)-4'-amine

57. Dispiro(cyclohexane-1,2'-(2h)indene-1'(3'h),2''-(2h)imidazol)-4''-amine, 4-methoxy-5''-methyl-6'-(5-(1-propyn-1-yl)-3-pyridinyl)-, (1.alpha.,1'r,4.beta.)-

2.4 Create Date
2012-11-30
3 Chemical and Physical Properties
Molecular Weight 412.5 g/mol
Molecular Formula C26H28N4O
XLogP33
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass412.22631153 g/mol
Monoisotopic Mass412.22631153 g/mol
Topological Polar Surface Area72.9 Ų
Heavy Atom Count31
Formal Charge0
Complexity827
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 1383984-21-1 / Lanabecestat API manufacturers, exporters & distributors?

Lanabecestat manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Lanabecestat API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Lanabecestat manufacturer or Lanabecestat supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Lanabecestat manufacturer or Lanabecestat supplier.

PharmaCompass also assists you with knowing the Lanabecestat API Price utilized in the formulation of products. Lanabecestat API Price is not always fixed or binding as the Lanabecestat Price is obtained through a variety of data sources. The Lanabecestat Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Lanabecestat

Synonyms

1383982-64-6, Azd-3293, Ly3314814, Azd3293, Lanabecestat [usan], X8spj492vf

Cas Number

1383984-21-1

Unique Ingredient Identifier (UNII)

X8SPJ492VF

About Lanabecestat

Lanabecestat is under investigation in clinical trial NCT03499041 (A Study of LY3314814 in Participants With Liver Impairment).

Lanabecestat Manufacturers

A Lanabecestat manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Lanabecestat, including repackagers and relabelers. The FDA regulates Lanabecestat manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Lanabecestat API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Lanabecestat Suppliers

A Lanabecestat supplier is an individual or a company that provides Lanabecestat active pharmaceutical ingredient (API) or Lanabecestat finished formulations upon request. The Lanabecestat suppliers may include Lanabecestat API manufacturers, exporters, distributors and traders.

Lanabecestat GMP

Lanabecestat Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Lanabecestat GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Lanabecestat GMP manufacturer or Lanabecestat GMP API supplier for your needs.

Lanabecestat CoA

A Lanabecestat CoA (Certificate of Analysis) is a formal document that attests to Lanabecestat's compliance with Lanabecestat specifications and serves as a tool for batch-level quality control.

Lanabecestat CoA mostly includes findings from lab analyses of a specific batch. For each Lanabecestat CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Lanabecestat may be tested according to a variety of international standards, such as European Pharmacopoeia (Lanabecestat EP), Lanabecestat JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Lanabecestat USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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