Evonik Evonik

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Find Clinical Drug Pipeline Developments & Deals for EIDD 2801

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            Details:

            Fermenta Biotech will exclusively license its biocatalytic technology for synthesis of Molnupiravir (Molflu) and supply its enzyme Candida Antarctica B Lipase (CAL B) to Aurigene. Molnupiravir API manufactured by Aurigene will be utilised by Dr Reddy’s for its formulation.

            Lead Product(s): Molnupiravir

            Therapeutic Area: Infections and Infectious Diseases Product Name: Molflu

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Fermenta Biotech Limited

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Licensing Agreement January 21, 2022

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            RDD 2024

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            Details:

            The licences are applicable for both molnupiravir (API) and finished product in capsules form. It enables the company to launch the product within India as well as export to 104 other countries around the world, Biophore India Pharmaceuticals said in a statement.

            Lead Product(s): Molnupiravir

            Therapeutic Area: Infections and Infectious Diseases Product Name: MK-4482

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: The Medicines Patent Pool

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Licensing Agreement January 20, 2022

            Details:

            Molflu a generic version of the Molnupiravir, is the first oral antiviral medication that helps treat mild to moderate COVID-19 in adults is expected to be available from next week in pharmacies throughout (India).

            Lead Product(s): Molnupiravir

            Therapeutic Area: Infections and Infectious Diseases Product Name: Molflu

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable January 04, 2022

            Details:

            Emergency-use authorisation recieved from DCGI to manufacture and market oral anti-viral drug Molflu (Molnupiravir) 200mg for treatment of adult patients with Covid19.

            Lead Product(s): Molnupiravir

            Therapeutic Area: Infections and Infectious Diseases Product Name: Molflu

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable December 29, 2021

            Details:

            DCGI approved Stripiravir (molnupiravir) an orally administered form of a potent ribonucleoside analog that inhibits the replication of SARS‐CoV‐2 in COVID-19 infection.

            Lead Product(s): Molnupiravir

            Therapeutic Area: Infections and Infectious Diseases Product Name: Stripiravir

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable December 28, 2021

            Details:

            Cipla Limited, Dr Reddy’s Laboratories Ltd, Emcure Pharmaceuticals, Sun Pharmaceutical Industries Limited and Torrent Pharmaceuticals will collaborate for the clinical trial of the oral anti-viral drug molnupiravir for mild Covid-19 in an outpatient setting in India.

            Lead Product(s): Molnupiravir

            Therapeutic Area: Infections and Infectious Diseases Product Name: MK-4482

            Highest Development Status: Phase III Product Type: Small molecule

            Partner/Sponsor/Collaborator: Cipla

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration June 29, 2021

            Details:

            Lagevrio (molnupiravir) is an investigational, orally administered nucleoside analog that accumulates errors in the viral genome leading in inhibition of SARS-CoV-2 replication, the causative agent of COVID-19.

            Lead Product(s): Molnupiravir

            Therapeutic Area: Infections and Infectious Diseases Product Name: Lagevrio

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Merck Group

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable February 24, 2023

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            Details:

            Lagevrio (molnupiravir) is an investigational, orally administered nucleoside analog that accumulates errors in the viral genome leading in inhibition of SARS-CoV-2 replication, the causative agent of COVID-19.

            Lead Product(s): Molnupiravir

            Therapeutic Area: Infections and Infectious Diseases Product Name: Lagevrio

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable February 21, 2023

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            Details:

            A preliminary analysis in highly-vaccinated adults mostly <65 years of age, showed no evidence of difference between LAGEVRIO (molnupiravir) added to usual care compared to usual care alone for reduction of hospitalizations and deaths through Day 28.

            Lead Product(s): Molnupiravir

            Therapeutic Area: Infections and Infectious Diseases Product Name: Lagevrio

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Ridgeback Biotherapeutics

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 06, 2022

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            Details:

            Analyses of pre-specied exploratory endpoints indicate that a lower proportion of LAGEVRIO (Molnupiravir)-treated participants in MTT population had an acute care visit or a COVID-19-related acute care visit versus placebo-treated participants in the MITT population.

            Lead Product(s): Molnupiravir

            Therapeutic Area: Infections and Infectious Diseases Product Name: Lagevrio

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Ridgeback Biotherapeutics

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable June 07, 2022

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