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    [{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2021","type":"Inapplicable","leadProduct":"Visugromab","moa":"GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Undisclosed"},{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2022","type":"Inapplicable","leadProduct":"Nivolumab","moa":"||GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Undisclosed"},{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2022","type":"Inapplicable","leadProduct":"Nivolumab","moa":"||GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Undisclosed"},{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2022","type":"Inapplicable","leadProduct":"Nivolumab","moa":"||GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Undisclosed"},{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2021","type":"Inapplicable","leadProduct":"Visugromab","moa":"GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Undisclosed"},{"orgOrder":0,"company":"CatalYm","sponsor":"Vesalius Biocapital III","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2020","type":"Series B Financing","leadProduct":"Visugromab","moa":"GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0.059999999999999998,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0.059999999999999998,"dosageForm":"Injection","sponsorNew":"CatalYm \/ Vesalius Biocapital III","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Vesalius Biocapital III"},{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2023","type":"Inapplicable","leadProduct":"Nivolumab","moa":"||GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Undisclosed"},{"orgOrder":0,"company":"CatalYm","sponsor":"Brandon Capital","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2022","type":"Series C Financing","leadProduct":"Nivolumab","moa":"||GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0.050000000000000003,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0.050000000000000003,"dosageForm":"Injection","sponsorNew":"CatalYm \/ Brandon Capital","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Brandon Capital"},{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2022","type":"Inapplicable","leadProduct":"Nivolumab","moa":"||GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Undisclosed"},{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2021","type":"Inapplicable","leadProduct":"Visugromab","moa":"GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Undisclosed"},{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2024","type":"Inapplicable","leadProduct":"Nivolumab","moa":"||GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Undisclosed"},{"orgOrder":0,"company":"CatalYm","sponsor":"Canaan Partners","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2024","type":"Series D Financing","leadProduct":"Nivolumab","moa":"||GDF15","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"CatalYm","amount2":0.14999999999999999,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.14999999999999999,"dosageForm":"Undisclosed","sponsorNew":"CatalYm \/ Canaan Partners","highestDevelopmentStatusID":"7","companyTruncated":"CatalYm \/ Canaan Partners"},{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2025","type":"Inapplicable","leadProduct":"Visugromab","moa":"GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Undisclosed"},{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Nutrition and Weight Loss","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2025","type":"Inapplicable","leadProduct":"Visugromab","moa":"GDF15","graph1":"Nutrition and Weight Loss","graph2":"Phase II\/ Phase III","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Infusion","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"9","companyTruncated":"CatalYm \/ Undisclosed"},{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2023","type":"Inapplicable","leadProduct":"Nivolumab","moa":"Programmed cell death protein 1","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Undisclosed"},{"orgOrder":0,"company":"CatalYm","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2025","type":"Inapplicable","leadProduct":"Visugromab","moa":"GDF15","graph1":"Oncology","graph2":"Phase II","graph3":"CatalYm","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"CatalYm \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"CatalYm \/ Undisclosed"}]

    Find Clinical Drug Pipeline Developments & Deals by CatalYm

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                            01

                            CatalYm

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                            Bio-Europe Autumn
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                            CatalYm

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                            Lead Product(s) : Visugromab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Visugromab, Nivolumab, TKI vs Placebo in Metastatic Liver Cancer

                            Details : CTL-002 (visugromab) is a antibody drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Carcinoma, Hepatocellular.

                            Product Name : CTL-002

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            October 21, 2025

                            Lead Product(s) : Visugromab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            CatalYm

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                            Bio-Europe Autumn
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                            Lead Product(s) : Visugromab

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Visugromab in Cachexia International Trial

                            Details : Visugromab is a Antibody drug candidate, which is currently being evaluated in Phase II/ Phase III clinical studies for the treatment of Cancer Cachexia.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            August 08, 2025

                            Lead Product(s) : Visugromab

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            CatalYm

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                            Bio-Europe Autumn
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                            Lead Product(s) : Visugromab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Visugromab + Immunochemotherapy In 1L Metastatic NSCLC

                            Details : Visugromab is a Antibody drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Carcinoma, Non-Small-Cell Lung.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            August 01, 2025

                            Lead Product(s) : Visugromab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            CatalYm

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                            Bio-Europe Autumn
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                            CatalYm

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                            Lead Product(s) : Visugromab,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Canaan Partners

                            Deal Size : $150.0 million

                            Deal Type : Series D Financing

                            DEALS_DEV arrow-down

                            CatalYm cashes in on early-stage cancer data with $150M series D

                            Details : The Proceeds will expand CTL-002 (visugromab) late-stage clinical development into earlier lines of treatment in combination with nivolumab for the treatment of bladder cancer.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            July 16, 2024

                            Lead Product(s) : Visugromab,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Canaan Partners

                            Deal Size : $150.0 million

                            Deal Type : Series D Financing

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                            05

                            CatalYm

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                            Bio-Europe Autumn
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                            CatalYm

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                            Lead Product(s) : Visugromab,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CatalYm Reports Lasting Responses in Late-Line NSCLC and Other Cancer Patients

                            Details : CTL-002 (visugromab) is a monoclonal antibody that neutralizes GDF-15 is being investigated in combination with nivolumab, a PD-1 inhibitor) in R/R non-small cell lung cancer (MIBC).

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            June 02, 2024

                            Lead Product(s) : Visugromab,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            CatalYm

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                            CatalYm

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                            Lead Product(s) : Visugromab,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CatalYm Commences Dosing in a Phase 2 Study with Visugromab in Combination with Neoadjuvant Immunotherapy in T...

                            Details : CTL-002 (Visugromab) is a monoclonal antibody that neutralizes the tumor-derived Growth Differentiation Factor-15 (GDF-15) in combination with neoadjuvant immunotherapy (nivolumab, aPD-1 inhibitor) in muscle invasive bladder cancer (MIBC).

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            October 26, 2023

                            Lead Product(s) : Visugromab,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            CatalYm

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                            CatalYm

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                            Lead Product(s) : Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neoadjuvant Immunotherapy Combined With the Anti-GDF-15 Antibody Visugromab to Treat Muscle Invasive Bladder C...

                            Details : Nivolumab is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Urinary Bladder Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            September 28, 2023

                            Lead Product(s) : Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            CatalYm

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                            Bio-Europe Autumn
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                            CatalYm

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                            Bio-Europe Autumn
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                            Lead Product(s) : Visugromab,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Brandon Capital

                            Deal Size : $51.8 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            CatalYm Closes EUR 50 Million Series C Financing to Expand and Accelerate Phase 2 Clinical Development of Visu...

                            Details : The financing will support the continued, promising clinical development of its lead candidate, visugromab, a humanized monoclonal antibody engineered to neutralize the tumor-produced Growth Differentiation Factor-15 (GDF-15).

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            November 22, 2022

                            Lead Product(s) : Visugromab,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Brandon Capital

                            Deal Size : $51.8 million

                            Deal Type : Series C Financing

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                            09

                            CatalYm

                            Germany arrow
                            Bio-Europe Autumn
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                            CatalYm

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                            Lead Product(s) : Visugromab,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CatalYm Receives FDA IND Clearance to Expand Development of Visugromab in Advanced Cancer Patients into the U....

                            Details : Visugromab, formerly known as CTL-002, is a monoclonal antibody that neutralizes GDF-15, a key immunosuppressor, which has been shown to prevent T cell migration into tumors, enabling cancerous cells to evade the immune system.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            September 26, 2022

                            Lead Product(s) : Visugromab,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            CatalYm

                            Germany arrow
                            Bio-Europe Autumn
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                            CatalYm

                            Germany arrow
                            Bio-Europe Autumn
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                            Lead Product(s) : Visugromab,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CatalYm Demonstrates Clinical Efficacy and Tolerability in First-in-Human Phase 1 Trial for Visugromab and Niv...

                            Details : Visugromab, formerly known as CTL-002, is a humanized, monoclonal antibody designed to neutralize the tumor-produced Growth Differentiation Factor-15 (GDF-15).

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            September 10, 2022

                            Lead Product(s) : Visugromab,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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