
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : BE-101
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Nextech
Deal Size : $92.0 million
Deal Type : Series C Financing
Be Bio Closes $92M Series C, Transitioning to Clinical Stage Company
Details : The proceeds from the financing will be used to advance the clinical development of BE-101, which is in the early-stage clinical trial for people with hemophilia B.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
January 15, 2025
Lead Product(s) : BE-101
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Nextech
Deal Size : $92.0 million
Deal Type : Series C Financing

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Lead Product(s) : BE-101
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Arch Ventures
Deal Size : $82.0 million
Deal Type : Financing
Be Bio Announces $82 Million Financing and Transition to Clinical Stage Company
Details : The financing is intended to support Be Bio in advancing BE-101 through clinical proof of concept, which is currently being evaluated for the treatment of hemophilia B.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
October 22, 2024
Lead Product(s) : BE-101
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Arch Ventures
Deal Size : $82.0 million
Deal Type : Financing

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Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Be Biopharma Shows Preclinical Efficacy of Engineered B Cell Medicine for Hypophosphatasia
Details : Be Biopharma's preclinical data showcases the transformative potential of BCMs in producing active alkaline phosphatase (ALP), positioning BCMs as a promising treatment for Hypophosphatasia.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
September 30, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : BE-101
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BE-101 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Hemophilia B.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
September 25, 2024
Lead Product(s) : BE-101
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : BE-101
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Be Bio’s haemophilia B treatment gains FDA orphan drug status
Details : BE-101 is an autologous B cell-derived ex vivo gene edited cell therapy candidate, whih is being evaluated for the treatment of patients with haemophilia B.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
June 05, 2024
Lead Product(s) : BE-101
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : BE-101
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Be Biopharma Announces FDA Clearance of IND Application for BE-101 in Hemophilia B
Details : BE-101 an autologous first-in-class B Cell Medicine that is engineered to insert the human FIX gene into primary human B cells, allowing for expression of active FIX for the treatment of hemophilia B.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
May 28, 2024
Lead Product(s) : BE-101
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Be Biopharma Reveals New Preclinical Data for B Cell Medicine Targeting Hypophosphatasia
Details : A therapy combining CRISPR/Cas9 and AI-guided protein design modifies primary human B cells to produce ALP, an enzyme deficient in Hypophosphatasia patients.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 10, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Recipient : MaxCyte
Deal Size : Undisclosed
Deal Type : Agreement
MaxCyte Signs License with Be Biopharma for Engineered B Cell Medicines
Details : Be Bio gains non-exclusive research, clinical, and commercial rights to use MaxCyte’s Flow Electroporation® technology and ExPERT platform to support the development of its BCMs programs.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
April 02, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Recipient : MaxCyte
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : BE-101
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BE-101 is a novel engineered B cell medicine, which produces active and sustained levels of Factor IX (FIX) and it is currently being evaluated for the treatment of hemophilia B.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
December 10, 2023
Lead Product(s) : BE-101
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Undisclosed
Sponsor : Arch Ventures
Deal Size : $130.0 million
Deal Type : Financing
Details : Proceeds will advance autologous and allogeneic Engineered B Cell Medicine (BeCM) platforms, as well as progress pipeline candidates in oncology and rare disease toward investigational new drug (IND) applications.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
April 14, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Sponsor : Arch Ventures
Deal Size : $130.0 million
Deal Type : Financing
