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Find Clinical Drug Pipeline Developments & Deals by Aristea Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          HPAPI Summit
                          Not Confirmed
                          HPAPI Summit
                          Not Confirmed

                          Details : RIST4721, is a solid oral dose that inhibits the activity of CXCR2. CXCR2 is a prominent cytokine receptor with an important role in the recruitment of neutrophils to the site of inflammation.

                          Product Name : RIST4721

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 02, 2023

                          Lead Product(s) : RIST4721

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          HPAPI Summit
                          Not Confirmed
                          HPAPI Summit
                          Not Confirmed

                          Details : The phase 2a study represents the second disease under investigation for the CXCR2 antagonist, RIST4721 and its initiation brings one step closer to potentially developing a treatment for HS.

                          Product Name : RIST4721

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 30, 2022

                          Lead Product(s) : RIST4721

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Arena Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          HPAPI Summit
                          Not Confirmed
                          HPAPI Summit
                          Not Confirmed

                          Details : RIST4721, an oral CXCR2 antagonist being developed by Aristea for the treatment of palmoplantar pustulosis (PPP) and other neutrophil-mediated diseases.

                          Product Name : RIST4721

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 30, 2022

                          Lead Product(s) : RIST4721

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          HPAPI Summit
                          Not Confirmed
                          HPAPI Summit
                          Not Confirmed

                          Details : Aristea has Phase 2a studies in development for RIST4721 in four additional CXCR2-mediated diseases: familial Mediterranean fever, Behcet's disease, hidradenitis suppurativa, and inflammatory bowel disease.

                          Product Name : RIST4721

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 28, 2022

                          Lead Product(s) : RIST4721

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          HPAPI Summit
                          Not Confirmed
                          HPAPI Summit
                          Not Confirmed

                          Details : RIST4721 is an oral CXCR2 antagonist being developed for the treatment of PPP with results reported from its Phase 2a clinical trial in 2020. Agreement Provides Arena with Exclusive Option to Acquire Aristea and its CXCR2 Programs post-Phase 2.

                          Product Name : RIST4721

                          Product Type : Other Small Molecule

                          Upfront Cash : $60.0 million

                          July 27, 2021

                          Lead Product(s) : RIST4721

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Arena Pharmaceuticals

                          Deal Size : $70.0 million

                          Deal Type : Collaboration

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                          06

                          HPAPI Summit
                          Not Confirmed
                          HPAPI Summit
                          Not Confirmed

                          Details : Aristea will use the proceeds of the financing to continue the build-out of its leadership team, the formation of new partnerships and the advancement of the development of its portfolio including RIST4721, programs to address orphan diseases.

                          Product Name : RIST4721

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          July 27, 2021

                          Lead Product(s) : RIST4721

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Fidelity Management & Research Company

                          Deal Size : $63.0 million

                          Deal Type : Series B Financing

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