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Find Clinical Drug Pipeline Developments & Deals by Amphera

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                          01

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : MesoPher (Autologous Tumor Lysate-Loaded Dendritic Cell) is comprised of autologous patient DCs loaded with “PheraLys” – Amphera’s allogeneic lysate of mesothelioma cell lines and being developed for pancreatic cancer.

                          Product Name : MesoPher

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          June 06, 2023

                          Lead Product(s) : MesoPher,Mitazalimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : The DENIM trial confirmed MesoPher’s excellent safety profile and MesoPher induced a robust T-cell response. The immune response did not translate into clinical benefit, and consequently the primary endpoint of an improvement of Overall Survival (OS) w...

                          Product Name : MesoPher

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          December 12, 2022

                          Lead Product(s) : MesoPher

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : The latest REACtiVe data for MesoPher showed an average Overall Survival after surgery of approximately 36 months, with 8 of 10 patients alive, which is far beyond expected survival.

                          Product Name : MesoPher

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          April 05, 2022

                          Lead Product(s) : MesoPher,Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : Patients received 3 bi-weekly injections of MesoPher, plus two further injections of MesoPher after 4 and 7 months. Patients in the control arm received best supportive care alone. The primary endpoint of the study is overall survival.

                          Product Name : MesoPher

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 08, 2022

                          Lead Product(s) : MesoPher

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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