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Therapy","year":"2020","type":"Inapplicable","leadProduct":"Cytarabine","moa":"||Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Sanofi","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Sanofi \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Sanofi \/ Undisclosed"},{"orgOrder":0,"company":"Sanofi","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Cell & Gene Therapy","year":"2020","type":"Inapplicable","leadProduct":"Cytarabine","moa":"||Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Sanofi","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Sanofi \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Sanofi \/ Undisclosed"}]

Find Clinical Drug Pipeline Developments & Deals for Alexan

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                          01

                          Details : The FDA approval of VENCLEXTA for newly-diagnosed AML patients who are ineligible for intensive chemotherapy is supported by data from a series of trials including two Phase 3 trials - VIALE-A (M15-656) and VIALE-C (M16-043).

                          Product Name : Venclexta

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 16, 2020

                          Lead Product(s) : Venetoclax,Cytarabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          02

                          Lead Product(s) : K-NK003,Cytarabine,Fludarabine Phosphate

                          Therapeutic Area : Oncology

                          Study Phase : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : The trial is expected to provide further clinical proof-of-concept of Kiadis’ K-NK003 product.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          June 25, 2020

                          Lead Product(s) : K-NK003,Cytarabine,Fludarabine Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          03

                          Details : AbbVie and Roche’s Venclexta has failed to significantly improve overall survival in an acute myeloid leukaemia (AML) trial that was supposed to confirm its efficacy.

                          Product Name : Venclexta

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          March 03, 2020

                          Lead Product(s) : Venetoclax,Cytarabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          04

                          Details : Study did not demonstrate statistically significant improvement in the primary endpoint of overall survival (OS) (Hazard Ratio [HR]=0.75, [95% CI 0.52 - 1.07], p=0.11)

                          Product Name : Venclexta

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 28, 2020

                          Lead Product(s) : Venetoclax,Cytarabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          05

                          Lead Product(s) : K-NK003,Cytarabine,Decitabine

                          Therapeutic Area : Oncology

                          Study Phase : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : The trial is expected to provide further clinical proof-of-concept of Kiadis’ K-NK003 product.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          February 26, 2020

                          Lead Product(s) : K-NK003,Cytarabine,Decitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          06

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Cytarabine is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Leukemia.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 01, 2025

                          Lead Product(s) : Cytarabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Children's Oncology Group

                          Country arrow
                          The MedTech Conference
                          Not Confirmed

                          Children's Oncology Group

                          Country arrow
                          The MedTech Conference
                          Not Confirmed

                          Details : Cytarabine is a Other Small Molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Leukemia, Myeloid, Acute.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 15, 2025

                          Lead Product(s) : Cytarabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : The Company’s lead program, Annamycin, is a next-generation highly efficacious and well tolerated anthracycline, in development for the treatment of relapsed or refractory AML and STS lung metastases.

                          Product Name : AnnAraC

                          Product Type : Antibiotic

                          Upfront Cash : Inapplicable

                          May 12, 2025

                          Lead Product(s) : Annamycin,Cytarabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : AnnAraC (naxtarubicin & cytarabine) is an antibiotic combination which targets DNA intercalation and topoisomerase II inhibition. Currently being investogated for R/R acute myeloid leukemia.

                          Product Name : AnnAraC

                          Product Type : Antibiotic

                          Upfront Cash : Inapplicable

                          May 06, 2025

                          Lead Product(s) : Annamycin,Cytarabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : SENTI-202 is a first-in-class off-the-shelf logic gated selective CD33 OR FLT3 cell therapy product candidate which eliminates CD33 and/or FLT3-expressing hematologic malignancies, such as AML.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          April 28, 2025

                          Lead Product(s) : SENTI-202,Cytarabine,Fludarabine Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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