CAS 303-26-4

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Also known as: 303-26-4, Norchlorcyclizine, 1-((4-chlorophenyl)(phenyl)methyl)piperazine, 1-[(4-chlorophenyl)phenylmethyl]piperazine, 130018-88-1, N-(p-chlorobenzhydryl)piperazine

Molecular Formula

C₁₇H₁₉ClN₂

Molecular Weight

286.8 g/mol

InChI Key

UZKBSZSTDQSMDR-UHFFFAOYSA-N

FDA UNII

T875VN0D6E

1 2D Structure

CAS 303-26-4

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-[(4-chlorophenyl)-phenylmethyl]piperazine

2.1.2 InChI

InChI=1S/C17H19ClN2/c18-16-8-6-15(7-9-16)17(14-4-2-1-3-5-14)20-12-10-19-11-13-20/h1-9,17,19H,10-13H2

2.1.3 InChI Key

UZKBSZSTDQSMDR-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1CN(CCN1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl

2.2 Other Identifiers

2.2.1 UNII

T875VN0D6E

2.3 Synonyms

2.3.1 MeSH Synonyms

1. N-(p-chlorobenzhydryl)piperazine

2. Norchlorcyclizine

3. Norchlorcyclizine Hydrochloride

4. Norchlorcyclizine Monohydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 303-26-4

2. Norchlorcyclizine

3. 1-((4-chlorophenyl)(phenyl)methyl)piperazine

4. 1-[(4-chlorophenyl)phenylmethyl]piperazine

5. 130018-88-1

6. N-(p-chlorobenzhydryl)piperazine

7. 1-[(4-chlorophenyl)(phenyl)methyl]piperazine

8. 4-(4-chlorobenzhydryl)piperazine

9. N-(4-chlorobenzhydryl)piperazine

10. 1-[(4-chlorophenyl)-phenylmethyl]piperazine

11. Cetirizine Impurity A

12. Nsc 86164

13. (-)-1-[(4-chlorophenyl)phenylmethyl]piperazine

14. Chlorobenzhydryl Piperazine

15. Levocetirizine Impurity 2

16. Mfcd00005965

17. Piperazine, 1-((4-chlorophenyl)phenylmethyl)-

18. Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-

19. (-)-1-[(4-chlorophenyl) Phenylmethyl] Piperazine

20. 4-chlorobenzhydryl Piperazine

21. Hydroxyzine Related Compound A

22. T875vn0d6e

23. 1-(.alpha.-phenyl-4-chlorobenzyl)piperazine

24. 1-(4-chloro-.alpha.-phenylbenzyl)piperazine

25. 1-[(4-chlorophenyl)-phenyl-methyl]piperazine

26. 4-chlorobenzhydrylpiperazine

27. Nsc-86164

28. 1-((4-chlorophenyl)phenylmethyl)piperazine

29. Piperazine, 1-(p-chloro-.alpha.-phenylbenzyl)-

30. (rs)-1-[(4-chlorophenyl)phenylmethyl]piperazine

31. 1-[(4-chlorophenyl)phenylmethyl)piperazine

32. Piperazine, 1-(.alpha.-(4-chlorophenyl)benzyl)-

33. Piperazine, 1-[.alpha.-(4-chlorophenyl)benzyl]-

34. Einecs 206-137-4

35. 1-(4-chlorodiphenylmethyl)piperazine

36. Brn 0243027

37. Unii-t875vn0d6e

38. 1-(4-chloro-alpha-phenylbenzyl)piperazine

39. 1-(alpha-phenyl-4-chlorobenzyl)piperazine

40. Piperazine, 1-(alpha-(4-chlorophenyl)benzyl)-

41. 1-(4-chlorobenzhydryl) Piperazine

42. Meclozine Impurity H

43. Cbhp

44. Cetirizine-m N-desalkyl

45. (s)-nor-ccz

46. Oprea1_771131

47. 4-23-00-00072 (beilstein Handbook Reference)

48. Mls000521343

49. Chembl81324

50. Schembl467086

51. Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-

52. Gtpl9162

53. Dtxsid00891490

54. Hms1648p05

55. Hms2464f07

56. N-(4-chlorobenzhydryl) Piperazine

57. Amy40892

58. Bcp08791

59. Bcp34517

60. Nsc86164

61. Norchlorcyclizine, (+/-)-

62. Bbl010366

63. Stk083473

64. Akos000268792

65. Akos016039386

66. Ac-3019

67. C 10c10

68. Cs-w001978

69. Gf-0133

70. Sb47944

71. N-(4-chlorophenyl)phenylmethylpiperazine

72. Ncgc00245963-01

73. Compound C10 [pmid: 24297249]

74. Smr000131751

75. Sy003580

76. Db-018556

77. C1611

78. Eu-0099994

79. Ft-0604324

80. Ft-0604325

81. Ft-0629215

82. Ft-0658637

83. Ft-0664913

84. 1-[(4-chlorophenyl)-phenylmethyl]-piperazine

85. En300-18220

86. Hydroxyzine Related Compound A [usp-rs]

87. N-[(4-chlorophenyl)(phenyl)-methyl]piperazine

88. (+/-)-1-(p-chlorobenzhydryl)piperazine

89. (-)-1-[(4chlorophenyl) Phenylmethyl]piperazine

90. 1-[(4-chloro-phenyl)-phenyl-methyl]-piperazine

91. (-)-1-[(4-chloro Phenyl)phenylmethyl]piperazine

92. 303c264

93. A806004

94. Sr-01000597190

95. (-)-1-[1-(4-chlorophenyl)phenylmethyl]piperazine

96. Q-200042

97. Sr-01000597190-1

98. (-)-1-[(4-chloro-phenyl)-phenyl-methyl]-piperazine

99. Q27076864

100. Z57388987

101. 1-(4-chlorobenzhydryl)piperazine, Technical Grade, 90%

102. Cetirizine Dihydrochloride Impurity A [ep Impurity]

103. Hydroxyzine Hydrochloride Impurity A [ep Impurity]

104. Meclozine Dihydrochloride Impurity H [ep Impurity]

105. Meclozine Impurity H, European Pharmacopoeia (ep) Reference Standard

106. Cetirizine Impurity A, European Pharmacopoeia (ep) Reference Standard

107. (r)-cetirizine Ep Impurity A;(r)-1-((4-chlorophenyl)(phenyl)methyl)piperazine

108. Hydroxyzine Related Compound A, United States Pharmacopeia (usp) Reference Standard

2.4 Create Date

2005-03-26

3 Chemical and Physical Properties

Molecular Formula	C₁₇H₁₉ClN₂
Molecular Weight	286.8 g/mol
XLogP3	3.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	3
Exact Mass	286.1236763 g/mol
Monoisotopic Mass	286.1236763 g/mol
Topological Polar Surface Area	15.3 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	277
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

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END USE APIs

01

Buclizine Hydrochloride

Jai Radhe Sales

India

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DK Pharmachem

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Fleming Laboratories

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Hema Pharmaceuticals Pvt....

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Nishchem International Pv...

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R L Fine Chem

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> 30 Yrs of Experience in Quality APIs & Intermediates Manufacturing

02

Cetirizine

Gonane Pharma

India

Gonane has API manufacturing expertise in new-age Corticosteroids, Hormones and other pharma raw materials.

Calyx Chemicals & Pharmac...

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DEAFARMA

Italy

Ipca Laboratories

India

NAM Group

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RA CHEM PHARMA LIMITED

India

03

Cetirizine Dihydrochloride

LGM Pharma

U.S.A

LGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

Seqens

France

Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients, & custom-made solutions to our customers.

Dr. Reddy's Laboratories

India

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Emay Pharmaceuticals

India

Emay Pharmaceuticals is a GMP-certified API manufacturing company.

Jai Radhe Sales

India

Jai Radhe Sales is your partner for all your sourcing needs.

Pharm-RX Chemical

U.S.A

Pharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

04

Levocetirizine Dihydrochloride

Granules India Limited

India

Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

LGM Pharma

U.S.A

LGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

Metrochem API Private Lim...

India

Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

Cohance Lifesciences

India

Cohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

DKSH

Switzerland

DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.

Dr. Reddy's Laboratories

India

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

05

Meclizine Hydrochloride

LGM Pharma

U.S.A

LGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

Cohance Lifesciences

India

Cohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

Jai Radhe Sales

India

Jai Radhe Sales is your partner for all your sourcing needs.

Pharm-RX Chemical

U.S.A

Pharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

Tenatra Chemie

India

Tenatra connects Indian manufacturers with global buyers through active partners in Germany, Switzerland, Belgium, Spain & Turkey.

Harika Drugs

India

Harika Drugs has been providing a qualitative range of Bulk Drugs/ APIs since 1993.

CAS 303-26-4 manufacturers and suppliers on PharmaCompass

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