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Details:

The agreements aim to support Aspen for commercialization of Sandostatin LAR Depot (octreotide acetate), which is indicated for long-term treatment of acromegaly & severe diarrhea and flushing episodes associated with metastatic carcinoid tumors.


Lead Product(s): Octreotide Acetate

Therapeutic Area: Endocrinology Product Name: Sandostatin LAR Depot

Highest Development Status: ApprovedProduct Type: Peptide

Recipient: Sandoz B2B

Deal Size: $99.9 million Upfront Cash: Undisclosed

Deal Type: Agreement December 04, 2023

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PNEUMOSIL® (pneumococcal polysaccharide conjugate vaccine – adsorbed, 10 Valent), a well-designed vaccine, provide comparable protection by targeting the most prevalent serotypes of the bacterium causing serious illness in developing countries.


Lead Product(s): Pneumococcal Polysaccharide Conjugate Vaccine

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: Pneumosil

Highest Development Status: ApprovedProduct Type: Vaccine

Partner/Sponsor/Collaborator: Gates Foundation

Deal Size: $30.0 million Upfront Cash: Undisclosed

Deal Type: Funding December 12, 2022

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ASPEN 2024

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Details:

PNEUMOSIL® (Pneumococcal Conjugate Vaccine – adsorbed, 10 Valent), a well-designed vaccine with relevant serotypes, provide comparable protection by targeting the most prevalent serotypes of the bacterium causing serious illness in developing countries.


Lead Product(s): 10 Valent Pneumococcal Polysaccharide Conjugate Vaccine

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: Pneumosil

Highest Development Status: ApprovedProduct Type: Vaccine

Partner/Sponsor/Collaborator: Serum Institute of India

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration August 31, 2022

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EIKANCE (atropine sulfate monohydrate eye drops) are available on prescription for children aged 4 to 14 years, as a treatment to slow the progression of myopia and may be initiated in children when myopia progresses by 1 or more diopters per year.


Lead Product(s): Atropine Sulfate

Therapeutic Area: Ophthalmology Product Name: Eikance

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 18, 2022

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Details:

Debiopharm to enter into this new alliance with Aspen, a well-established and trusted pharmaceutical partner for the commercialization of Trelstar® in South Africa and recognize the therapeutic benefits that Trelstar® could bring to prostate cancer patients in this region.


Lead Product(s): Triptorelin Pamoate

Therapeutic Area: Oncology Product Name: Trelstar

Highest Development Status: ApprovedProduct Type: Peptide

Partner/Sponsor/Collaborator: Debiopharm

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership February 01, 2022

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ASPEN 2024

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Details:

The license under discussion would enable Aspen, using COVID-19 vaccine JNJ-78436735, drug substance supplied by Johnson & Johnson, to produce Aspen-branded finished vaccine for sale to public sector markets in Africa.


Lead Product(s): Ad26.COV2.S

Therapeutic Area: Infections and Infectious Diseases Product Name: JNJ-78436735

Highest Development Status: ApprovedProduct Type: Vaccine

Partner/Sponsor/Collaborator: Johnson & Johnson

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement November 30, 2021

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ASPEN 2024

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Details:

The transaction includes Trustan, Altosec, Zuvamor, Ciavor, Grantryl and Aspen Granisetron brands. To secure uninterrupted patient access to these medicines, the parties have also signed a manufacturing and supply agreement.


Lead Product(s): Esomeprazole Magnesium

Therapeutic Area: Gastroenterology Product Name: Trustan

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Acino Pharma AG

Deal Size: $119.4 million Upfront Cash: Undisclosed

Deal Type: Acquisition October 22, 2021

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ASPEN 2024

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Details:

Avion Pharmaceuticals gets exclusive rights to relaunch Cenestin® in the USA. Cenestin® is the only plant-derived mixture of nine conjugated estrogens indicated for treatment of moderate to severe symptoms of vasomotor, and vulvar and vaginal atrophy due to menopause.


Lead Product(s): Conjugated Estrogens

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Product Name: Cenestin

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Avion Pharmaceuticals

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership November 12, 2020

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ASPEN 2024

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Details:

Under the terms of the agreement, Mylan Ireland Limited will acquire the commercialisation rights and related intellectual property relating to Aspen’s Thrombosis Business in Europe which includes Arixtra, Fraxiparine, Mono-Embolex and Orgaran.


Lead Product(s): Fondaparinux Sodium

Therapeutic Area: Cardiology/Vascular Diseases Product Name: Arixtra

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Viatris

Deal Size: $757.2 million Upfront Cash: $310.4 million

Deal Type: Acquisition September 08, 2020

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ASPEN 2024

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Details:

The acquisition strengthens Sandoz’s presence in the hospital channel by complementing the broad Sandoz portfolio and pipeline of hospital generic and biosimilar products in Japan like Lidocaine Hydrochloride.


Lead Product(s): Lidocaine Hydrochloride

Therapeutic Area: Neurology Product Name: Lidocaine HCl-Generic

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Sandoz B2B

Deal Size: $440.0 million Upfront Cash: $330.0 million

Deal Type: Acquisition January 31, 2020

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ASPEN 2024

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