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    Chemistry

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    Also known as: Morphine sulfate, Schembl29317, Morphinesulfatenarcoticanalgesic
    Molecular Formula
    C17H21NO7S
    Molecular Weight
    383.4  g/mol
    InChI Key
    OOZBZVAQKFGLOL-VYKNHSEDSA-N
    Morphine Sulfate
    The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.
    1 2D Structure

    Morphine Sulfate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol;sulfuric acid
    2.1.2 InChI
    InChI=1S/C17H19NO3.H2O4S/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18;1-5(2,3)4/h2-5,10-11,13,16,19-20H,6-8H2,1H3;(H2,1,2,3,4)/t10-,11+,13-,16-,17-;/m0./s1
    2.1.3 InChI Key
    OOZBZVAQKFGLOL-VYKNHSEDSA-N
    2.1.4 Canonical SMILES
    CN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O.OS(=O)(=O)O
    2.1.5 Isomeric SMILES
    CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O.OS(=O)(=O)O
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Chloride, Morphine

    2. Contin, Ms

    3. Duramorph

    4. Morphia

    5. Morphine

    6. Morphine Chloride

    7. Morphine Sulfate

    8. Morphine Sulfate (2:1), Anhydrous

    9. Morphine Sulfate (2:1), Pentahydrate

    10. Ms Contin

    11. Oramorph Sr

    12. Sdz 202 250

    13. Sdz 202-250

    14. Sdz 202250

    15. Sdz202 250

    16. Sdz202-250

    17. Sdz202250

    18. Sulfate, Morphine

    2.2.2 Depositor-Supplied Synonyms

    1. Morphine Sulfate

    2. Schembl29317

    3. Morphinesulfatenarcoticanalgesic

    2.3 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 383.4 g/mol
    Molecular Formula C17H21NO7S
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count0
    Exact Mass383.10387318 g/mol
    Monoisotopic Mass383.10387318 g/mol
    Topological Polar Surface Area136 Ų
    Heavy Atom Count26
    Formal Charge0
    Complexity576
    Isotope Atom Count0
    Defined Atom Stereocenter Count5
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 6  
    Drug NameAstramorph pf
    PubMed HealthMorphine (Injection)
    Active IngredientMorphine sulfate
    Dosage FormInjectable
    RouteInjection
    Strength1mg/ml; 0.5mg/ml
    Market StatusPrescription
    CompanyFresenius Kabi Usa

    2 of 6  
    Drug NameDuramorph pf
    Active IngredientMorphine sulfate
    Dosage FormInjectable
    RouteInjection
    Strength1mg/ml; 0.5mg/ml
    Market StatusPrescription
    CompanyHikma Maple

    3 of 6  
    Drug NameMorphine sulfate
    PubMed HealthMorphine Sulfate Liposome (Injection)
    Drug ClassesAnalgesic, Anesthetic Adjunct, Central Nervous System Agent
    Drug LabelDESCRIPTIONChemically, morphine sulfate is 7, 8-didehydro-4, 5-epoxy-17-methylmorphinan-3, 6-diol sulfate (2:1) (salt) pentahydrate...
    Active IngredientMorphine sulfate
    Dosage FormTablet, extended release; Tablet; Injectable; Capsule, extended release; Solution
    RouteIntramuscular, intravenous; oral; Injection; Oral
    Strength2mg/ml; 200mg; 10mg/5ml; 1mg/ml; 8mg/ml (8mg/ml); 30mg; 10mg/ml (10mg/ml); 100mg/5ml; 90mg; 15mg; 120mg;