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19925 Stevens Creek Blvd., Suite 100 Cupertino, CA 95014
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RP5063 (brilaroxazine), an atypical antipsychotic new chemical entity with potent affinity and selectivity against key serotonin and dopamine receptors, is being developed for the treatment of schizophrenia.


Lead Product(s): Brilaroxazine

Therapeutic Area: Psychiatry/Psychology Product Name: RP5063

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 15, 2024

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The net proceeds will fund research and development activities, including the registrational Phase 3 RECOVER-2 trial evaluating RP5063 (brilaroxazine), an in-house discovered new chemical entity with potent affinity and selectivity against key serotonin and dopamine receptors.


Lead Product(s): Brilaroxazine

Therapeutic Area: Dermatology Product Name: RP5063

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: H.C. Wainwright & Co.

Deal Size: $30.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering November 20, 2023

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The net proceeds will fund research and development activities, including the registrational Phase 3 RECOVER-2 trial evaluating RP5063 (brilaroxazine), an in-house discovered new chemical entity with potent affinity and selectivity against key serotonin and dopamine receptors.


Lead Product(s): Brilaroxazine

Therapeutic Area: Dermatology Product Name: RP5063

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: H.C. Wainwright & Co.

Deal Size: $30.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering November 16, 2023

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Details:

RP5063 (brilaroxazine), an atypical antipsychotic new chemical entity with potent affinity and selectivity against key serotonin and dopamine receptors, is being developed for the treatment of schizophrenia.


Lead Product(s): Brilaroxazine

Therapeutic Area: Psychiatry/Psychology Product Name: RP5063

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 30, 2023

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Details:

RP5063 (brilaroxazine), an atypical antipsychotic new chemical entity with potent affinity and selectivity against key serotonin and dopamine receptors, is being developed for the treatment of schizophrenia.


Lead Product(s): Brilaroxazine

Therapeutic Area: Dermatology Product Name: RP5063

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 25, 2023

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RP5063 (brilaroxazine) is selectivity against key serotonin and dopamine receptors implicated in schizophrenia and its comorbid symptoms. In a multinational, multicenter, double-blind Phase 2 study in 234 patients with acute schizophrenia or schizoaffective disorder.


Lead Product(s): Brilaroxazine

Therapeutic Area: Psychiatry/Psychology Product Name: RP5063

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 17, 2023

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Details:

RP5063 (brilaroxazine), an atypical antipsychotic new chemical entity with potent affinity and selectivity against key serotonin and dopamine receptors, is being developed for the treatment of schizophrenia.


Lead Product(s): Brilaroxazine

Therapeutic Area: Psychiatry/Psychology Product Name: RP5063

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 22, 2023

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Details:

RP5063 (brilaroxazine, a topical liposomal-gel formulation) is a modulator of D and 5-HT receptors with multifaceted activity that may affect underlying psoriasis pathology.


Lead Product(s): Brilaroxazine

Therapeutic Area: Dermatology Product Name: RP5063

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 11, 2023

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Details:

Brilaroxazine (RP5063) is a new chemical entity with potent affinity and selectivity against key serotonin and dopamine receptors implicated in schizophrenia and its comorbid symptoms.


Lead Product(s): Brilaroxazine

Therapeutic Area: Psychiatry/Psychology Product Name: RP5063

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 15, 2022

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Details:

The Canadian patent covers the compositions of novel RP1208, phenylcycloalkylmethylamine derivatives and the use of the compositions for the treatment of obesity, and related co-morbid conditions and depression and related co-morbid conditions.


Lead Product(s): RP1208

Therapeutic Area: Psychiatry/Psychology Product Name: RP1208

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 21, 2022

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