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    Pharma Services Category of Dishman Carbogen Amcis

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    HTL Biotechnology is the world leader in the responsible development and production of pharmaceutical-grade biopolymers.
    Polpharma is a Polish CDMO of APIs and a significant European API producer, delivering products to companies worldwide.
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    01 API Development (1)

    02 Active Pharmaceutical Ingredients (1)

    03 Analytical Method Development (2)

    04 Analytical Testing Services (8)

    05 Chromatography (1)

    06 Clinical Supply (1)

    07 Contract Manufacturing (1)

    08 Cytotoxic Compound (1)

    09 Fine Chemical / Intermediate (1)

    10 Formulation Development (3)

    11 GMP Manufacturing (1)

    12 High Potency APIs (HPAPIs) (1)

    13 Lyophilization (1)

    14 Preformulation & Material Science (1)

    15 Process Development & Optimization (1)

    16 Scale Up (1)

    17 Small Scale Batch (1)

    18 Softgel Capsule (1)

    19 Stability Studies (2)

    20 Vitamins / Minerals / Inorganic Salts (1)

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    Dishman Carbogen Amcis

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    PROCESS DEVELOPMENT TO COMMERCIALIZATION

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    Dishman's business focuses on high-value, cost-competitive contract development & manufacturing services: process development, process optimisation, manufacture for late stage clinical and commercialization.

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    Pharma Service: API Manufacturing

    Category: Process Development & Optimization

    Sub Category: Overview
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    LATE STAGE CLINICAL SUPPLY

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    Dishman's CRAMS business offers a range of high-value, cost competitive contract services. It includes process development, process optimization, manufacture for late stage clinical & commercial supply.

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    Pharma Service: API Manufacturing

    Category: Clinical Supply

    Sub Category: Overview
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    ADVANCED INTERMEDIATES & SPECIALITY CHEMICALS

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    The Dishman CRAMS business offers an unparalleled range of facilities dedicated to contract manufacture of APIs, Highly Potent APIs (HPAPIs) and advanced intermediates & speciality chemicals for pharmaceutical customers.

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    Pharma Service: API Manufacturing

    Category: Fine Chemical / Intermediate

    Sub Category: Overview
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    PRECLINICAL TO LARGE SCALE

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    Dishman Custom Services, comprising both the CARBOGEN AMCIS and Dishman CRAMS businesses. We operate seamlessly across the entire lifecycle of a product, having an ability to manage projects from preclinical through to commercial scale manufacture.

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    Pharma Service: API Manufacturing

    Category: Scale Up

    Sub Category: Overview
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    HIGHLY POTENT API (HPAPI) MANUFACTURING

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    The Dishman Group offers unparalleled capabilities in scale-up, development and commercial manufacture of highly potent APIs (HPAPIs) and vitamins. All its facilities operate under cGMP conditions.

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    Pharma Service: API Manufacturing

    Category: High Potency APIs (HPAPIs)

    Sub Category: Overview
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    TECHNOLOGY TRANSFER CDMO SERVICES

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    Dishman provides efficient technology transfer CDMO services. For a seamless technical transfer, a specialist team follows an established three stage procedure to fulfill their partners' needs.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Tech Transfer
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    ANALYTICAL CHARACTERIZATION

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    Dishman's offers various analytical characterization services such as Structure Elucidation, Physical Characterization, Polymorphism Investigation, DSC, XPRD, FTIR studies, Particle sizing, Impurity Profiling & Identification, Formulation studies, etc

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    Pharma Service: Analytical

    Category: Analytical Testing Services

    Sub Category: Structure Elucidation
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    PARTICLE SIZING

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    Dishman's offers various analytical characterization services such as Structure Elucidation, Physical Characterization, Polymorphism Investigation, DSC, XPRD, FTIR studies, Particle sizing, Impurity Profiling & Identification, Formulation studies, etc

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    Pharma Service: Analytical

    Category: Analytical Testing Services

    Sub Category: Particle Size
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    PROCESS CONTROL & MATERIAL CHARACTERIZATION

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    Dishman strives to provides analytical services support in both process control and material characterization for laboratory and production chemistry from initial raw material release to release of the final APIs.

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    Pharma Service: Analytical

    Category: Analytical Method Development

    Sub Category: Impurity Isolation and Identification
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    PHYSICAL CHARACTERISATION

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    Dishman's offers various analytical characterization services such as Structure Elucidation, Physical Characterization, Polymorphism Investigation, DSC, XPRD, FTIR studies, Particle sizing, Impurity Profiling & Identification, Formulation studies, etc

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    Pharma Service: Analytical

    Category: Analytical Testing Services

    Sub Category: Physical Characterization
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    SEPARATION & PURIFICATION OF APIs

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    Dishman's anlaytical services support offers various Chromatography services for separation & purification of APIs such as HPLC (DAD, UV, RI), Ion Chromatography, HPLC-MS, GC (FID, NPD), GC (Head Space), GC-MS and TLC with scanner.

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    Pharma Service: API Manufacturing

    Category: Chromatography

    Sub Category: Overview
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    IMPURITY PROFILING & IDENTIFICATION

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    Dishman's offers various analytical characterization services such as Structure Elucidation, Physical Characterization, Polymorphism Investigation, DSC, XPRD, FTIR studies, Particle sizing, Impurity Profiling & Identification, Formulation studies, etc

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    Pharma Service: Analytical

    Category: Analytical Testing Services

    Sub Category: Impurity Isolation and Identification
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    POLYMORPHISM INVESTIGATION

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    Dishman's offers various analytical characterization services such as Structure Elucidation, Physical Characterization, Polymorphism Investigation, DSC, XPRD, FTIR studies, Particle sizing, Impurity Profiling & Identification, Formulation studies, etc

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    Pharma Service: Analytical

    Category: Analytical Testing Services

    Sub Category: XRPD
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    FTIR SPECTROSCOPY

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    Dishman's offers various analytical characterization services such as Structure Elucidation, Physical Characterization, Polymorphism Investigation, DSC, XPRD, FTIR Spectroscopy, Particle sizing, Impurity Profiling & Identification, Formulation studies,etc

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    Pharma Service: Analytical

    Category: Analytical Testing Services

    Sub Category: FTIR / NIR
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    METHOD DEVELOPMENT & VALIDATION

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    Dishman's analytical services support both process control and material characterization including method development & validation for laboratory and production chemistry from initial raw material release to release of the final APIs.

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    Pharma Service: Analytical

    Category: Analytical Method Development

    Sub Category: Method Development and Validation
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    STRESSING TESTS & PHOTOSTABILITY STUDIES

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    Dishman offers various analytical services under Stability which includes ICH Stability Studies, Stressing Studies, Photostability Studies, Drug Substance & Drug Product Stability and Degradation profiling.

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    Pharma Service: Analytical

    Category: Stability Studies

    Sub Category: Photostability
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    ICH STABILITY STUDIES/DEGRADATION PROFILING

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    Dishman offers various analytical services under Stability which includes ICH Stability Studies, Stressing Studies, Photostability Studies, Drug Substance & Drug Product Stability and Degradation profiling.

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    Pharma Service: Analytical

    Category: Stability Studies

    Sub Category: Overview
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    CONTENT & PURITY TESTING

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    Dishman's anlaytical services support offers various spectroscopy services to determine the content & purity of a sample with NMR 400 MHz, FTIR, ICP, CHN, XRD, UV-Spectrophotomtry, Polarimetry.

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    Pharma Service: Analytical

    Category: Analytical Testing Services

    Sub Category: Solid State NMR
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    ANALYSIS OF HIGHLY POTENT APIs

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    Dishman's analytical services support both process control and material characterisation for laboratory and production chemistry from initial raw material release to release of the final APIs including Analysis of Highly Potent APIs.

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    Pharma Service: Analytical

    Category: Analytical Testing Services

    Sub Category: UV Spectrophotometry
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    API/HPAPI/INTERMEDIATE CONTRACT MANUFACTURER

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    The Dishman CRAMS business offers an unparalleled range of facilities dedicated to contract manufacture of APIs, Highly Potent APIs (HPAPIs) and advanced intermediates & speciality chemicals for pharmaceutical customers.

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    Pharma Service: API Manufacturing

    Category: Contract Manufacturing

    Sub Category: Overview
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    LAB SCALE TO LARGE SCALE MANUFACTURING

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    Our state-of–the-art infrastructure includes manufacturing capabilities for small batch sizes of up to 10-15 kg. The specialised laboratories and kilo-scale manufacturing equipment are designed to operate safely at or below 1 ?g/m³ OEL

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    Pharma Service: API Manufacturing

    Category: Small Scale Batch

    Sub Category: Overview
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    cGMP MANUFACTURING

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    Dishman is committed to current Good Manufacturing Practices (cGMP) procedures and ensure that our global manufacturing sites adhere fully to our internal GMP policies, local regulations and the international guidelines associated with the USFDA

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    Pharma Service: API Manufacturing

    Category: GMP Manufacturing

    Sub Category: Overview
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    CYTOTOXICS / CYTOSTATICS MANUFACTURING

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    Dishman's specialised laboratories and kilo-scale contract manufacturing equipment are designed to operate safely. This specification allows the safe handling of highly-potent compounds of all categories including cytotoxics / cytostatics.

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    Pharma Service: API Manufacturing

    Category: Cytotoxic Compound

    Sub Category: Overview
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    LYOPHILIZATION CAPABILITY

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    The dedicated expansion in Bavla, India offers large scale manufacturing capabilities with a safe operation at or below 1 ?g/m³ OEL on a scale up to 1600L in the 200kg range batches, particle size reduction capability and lyophilization capability etc

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    Pharma Service: API Manufacturing

    Category: Lyophilization

    Sub Category: Overview
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    VITAMIN MANUFACTURING

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    Dishman Netherlands plant manufacturing cholesterol, serving as a precursor to vitamin D & its analogues. We forayed into developing a wide spectrum of products for the pharmaceutical, nutraceutical and holistic animal nutrition verticals of Vitamin D3.

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    Pharma Service: API Manufacturing

    Category: Vitamins / Minerals / Inorganic Salts

    Sub Category: Overview
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    SCALE UP & DEVELOPMENT OF HPAPIs

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    The Dishman Group offers unparalleled capability in scale-up, development and commercial manufacture of highly potent APIs, compounds and vitamins.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: Scale-Up Capabilities
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    SCALE UP & FORMULATION DEVELOPMENT OF HPAPIs

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    The Dishman Group offers unparalleled support service capabilities in scale-up, development and commercial manufacture of HPAPIs (more potent APIs), compounds and vitamins.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Scale-Up Capabilities
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    PARTICLE SIZE REDUCTION CAPABILITY

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    Dishman has a dedicated facility in Bavla, India, that offers large-scale manufacturing capabilities with safe operations at or below 1 mg/m³ OEL on a scale up to 1,600 litres, along with particle size reduction and lyophilization capability, etc.

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    Pharma Service: API & Drug Product Development

    Category: Preformulation & Material Science

    Sub Category: Particle Size Reduction & Micronization
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    DEVELOPMENT OF SOFT GEL CAPSULES

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    Dishman has largely indulged in developing sophisticated infrastructure which enables the manufacturing of various novel dosage forms in soft gelatine capsules, such as therapeutic, nutraceutical, enteric-coated and cosmeceuticals.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Softgel Capsule
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    SOFTGEL CAPSULES MANUFACTURING

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    Dishman offers a commercial softgel facility equipped with 2 encapsulation machine lines having a capacity of 60 million capsules/month, with the capabilities to produce all the different types of dosage fills and shapes of capsules

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    Pharma Service: Drug Product Manufacturing

    Category: Softgel Capsule

    Sub Category: Overview
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    REGULATORY SUPPORT

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    We also provide substantial regulatory expertise and support, development of DMFs, CTDs for advanced intermediates and final APIs, strong technology offering to both the generic and ethical pharmaceutical industry

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    Pharma Service: Sales, Marketing, Registration

    Category: Active Pharmaceutical Ingredients

    Sub Category: India
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