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USDMF
CEP/COS
JDMF
WC
Looking for 1480724-61-5 / Vosoritide API manufacturers, exporters & distributors?
Vosoritide manufacturers, exporters & distributors
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API | Excipient name
Vosoritide
Synonyms
Voxzogo, Bmn 111, Bmn-111, Vosoritide [usan:inn], Unii-7se5582q2p, 1480724-61-5
About Vosoritide
Achondroplasia is an autosomal dominant genetic disease and the most common cause of dwarfism in humans. It results from a gain-of-function missense mutation in FGFR3 that results in a dramatic suppression of bone growth, both in volume and in length. Treatment for achondroplasia includes both surgical and pharmacological interventions, the latter of which includes C-type natriuretic peptide (CNP) analogs. Endogenous CNP, first described in 1998, is primarily responsible for the stimulation of chondrocytes and long bone growth via activity at the NPR-B receptor, making it an attractive target in the treatment of a condition like achondroplasia. While the remarkably short half-life of endogenous CNP - 2 to 3 minutes due to its rapid degradation by endopeptidases - makes it ineffective as a therapeutic intervention, the development of a peptidase-resistant formulation has allowed for its use as a viable treatment option in achondroplasia. Vosoritide is an analog of CNP with proline-glycine on its N-terminus to convey resistance to neutral endopeptidase. It was approved for use under the brand name Voxzogo (BioMarin Pharmaceutical Inc.) in the EU in August 2021 and the US in November 2021, becoming the first pharmacological intervention approved for the treatment of achondroplasia in both regions.
Vosoritide Manufacturers
A Vosoritide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Vosoritide, including repackagers and relabelers. The FDA regulates Vosoritide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Vosoritide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Vosoritide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
Vosoritide Suppliers
A Vosoritide supplier is an individual or a company that provides Vosoritide active pharmaceutical ingredient (API) or Vosoritide finished formulations upon request. The Vosoritide suppliers may include Vosoritide API manufacturers, exporters, distributors and traders.
click here to find a list of Vosoritide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
Vosoritide Manufacturers | Traders | Suppliers
Vosoritide Manufacturers, Traders, Suppliers
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We have 1 companies offering Vosoritide
Get in contact with the supplier of your choice:
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Aspen API
Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Market Place
Aspen API. More than just an API. 
