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    Obefazimod

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    Maithri Drugs

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Looking for 1258453-75-6 / Obefazimod API manufacturers, exporters & distributors?

    Obefazimod manufacturers, exporters & distributors 1

    49

    PharmaCompass offers a list of Obefazimod API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Obefazimod manufacturer or Obefazimod supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Obefazimod manufacturer or Obefazimod supplier.

    API | Excipient name

    Obefazimod

    Synonyms

    Abx-464, Abx464, 1258453-75-6, Spl-464, Obefazimod [usan], 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine

    Cas Number

    1258453-75-6

    Unique Ingredient Identifier (UNII)

    26RU378B9V

    About Obefazimod

    Obefazimod is an orally available, small molecule binder of the cap binding complex (CBC) 80/20, with potential antiviral and anti-inflammatory activities. Upon oral administration, obefazimod binds to the CBC, a complex at the 5'-end of the pre-mRNA transcript that promotes the initial interaction with transcription and processing machinery. This leads to a conformational change in the CBC and enhanced splicing of viral RNA variants and upregulation of the anti-inflammatory microRNA, miR-124, via splicing of a long noncoding RNA at the miR-124-1 locus. In human immunodeficiency virus type 1 (HIV-1)-infected cells, obefazimod interacts with the CBC of HIV-1 mRNA and inhibits viral replication by preventing Rev-mediated export of unspliced HIV-1 transcripts to the cytoplasm. Rev facilitates the nuclear export of unspliced or incompletely spliced viral pre-mRNAs, an essential step in HIV-1 replication. In inflammatory conditions, miR-124 reduces the production of various inflammatory mediators, including interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-alpha), and C-C motif chemokine 2 (CCL2; MCP-1.). miR-124 plays a critical role in innate and adaptive immune responses and is a critical mediator of cholinergic anti-inflammatory action.

    Obefazimod Manufacturers

    A Obefazimod manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Obefazimod, including repackagers and relabelers. The FDA regulates Obefazimod manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Obefazimod API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Obefazimod manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

    Obefazimod Suppliers

    A Obefazimod supplier is an individual or a company that provides Obefazimod active pharmaceutical ingredient (API) or Obefazimod finished formulations upon request. The Obefazimod suppliers may include Obefazimod API manufacturers, exporters, distributors and traders.

    click here to find a list of Obefazimod suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

    Obefazimod Manufacturers | Traders | Suppliers

    Obefazimod Manufacturers, Traders, Suppliers 1
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    We have 1 companies offering Obefazimod

    Get in contact with the supplier of your choice:

    1. Maithri Drugs
    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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