Linaclotide API Manufacturers | Suppliers | Drug Master Files (DMF) | CEP

PharmaCompass offers a list of Linaclotide API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Linaclotide manufacturer or Linaclotide supplier for your needs.

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PharmaCompass also assists you with knowing the Linaclotide API Price utilized in the formulation of products. Linaclotide API Price is not always fixed or binding as the Linaclotide Price is obtained through a variety of data sources. The Linaclotide Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Linaclotide

Synonyms

Linzess, 851199-59-2, Chebi:68551, Md-1100, Constella, Cys cys glu tyr cys cys asn pro ala cys thr gly cys tyr (disulfide bridge: 1-6; 2-10; 5-13)

Cas Number

851199-59-2

About Linaclotide

Linaclotide is a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is structurally related to the guanylin peptide family, with secretagogue, analgesic and laxative activities. Upon oral administration, linaclotide binds to and activates GC-C receptors located on the luminal surface of the intestinal epithelium. This increases the concentration of intracellular cyclic guanosine monophosphate (cGMP), which is derived from guanosine triphosphate (GTP). cGMP activates the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates the secretion of chloride and bicarbonate into the intestinal lumen. This promotes sodium excretion into the lumen and results in increased intestinal fluid secretion. This ultimately accelerates GI transit of intestinal contents, improves bowel movement and relieves constipation. Increased extracellular cGMP levels may also exert an antinociceptive effect, through an as of yet not fully elucidated mechanism, that may involve modulation of nociceptors found on colonic afferent pain fibers. Linaclotide is minimally absorbed from the GI tract.

Linaclotide Manufacturers

A Linaclotide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Linaclotide, including repackagers and relabelers. The FDA regulates Linaclotide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Linaclotide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Linaclotide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Linaclotide Suppliers

A Linaclotide supplier is an individual or a company that provides Linaclotide active pharmaceutical ingredient (API) or Linaclotide finished formulations upon request. The Linaclotide suppliers may include Linaclotide API manufacturers, exporters, distributors and traders.

click here to find a list of Linaclotide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Linaclotide Manufacturers | Traders | Suppliers

We have 25 companies offering Linaclotide

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Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

List of all Manufacturers, Suppliers & Exporters of Linaclotide API listed on PharmaCompass with details of regulatory filings

Linaclotide

Synopsis

Chemistry

APIs // Active Pharmaceutical Ingredients

28 Suppliers

11 USDMF

1 JDMF

2 EU WC

6 NDC API

20 Listed Suppliers

DEVELOPMENTS

11 Drug(s) in Development

PRICE INFORMATION

API Reference Price

API Exports

API Imports

FDF Exports

FDF Imports

DOSSIERs // Finished Dosage Forms

18 Dossiers

8 FDA Orange Book

5 Europe

3 Canada

2 Listed Dossiers

DRUG PRODUCT COMPOSITION

CAPSULE;ORAL - 145MCG

CAPSULE;ORAL - 290MCG

CAPSULE;ORAL - 72MCG

RELATED EXCIPIENT COMPANIES

Suppliers

17 Kerry

10 Corel Pharma Chem

9 Roquette

9 Sigachi Industries

7 Ideal Cures Pvt Ltd

6 Lonza Capsugel

6 Gangwal Chemicals

6 Seppic

5 Gangwal Healthcare

4 Microlex e.U

4 ACG Worldwide

3 Kima Chemical

2 DKSH

2 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

2 Qualicaps

2 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

2 The Dow Chemical Company

2 DFE Pharma

1 Finar

1 Evonik

1 Aeon Procare

1 Vasa Pharmachem

1 Prachin Chemical

1 SPI Pharma

1 Actylis

1 BASF

1 Qianhao Chemical (Hebei) Co., Ltd

1 Pharmatrans-Sanaq

EXCIPIENTS BY APPLICATIONS

46 Coating Systems & Additives

24 Controlled & Modified Release

20 Fillers, Diluents & Binders

12 Direct Compression

9 Disintegrants & Superdisintegrants

9 Empty Capsules

9 Thickeners and Stabilizers

7 Film Formers & Plasticizers

7 Granulation

6 Co-Processed Excipients

5 Lubricants & Glidants

5 Taste Masking

4 Vegetarian Capsules

4 API Stability Enhancers

3 Chewable & Orodispersible Aids

3 Parenteral

2 Coloring Agents

2 Topical

2 Rheology Modifiers

1 Solubilizers