Larotrectinib Sulfate API Manufacturers | Suppliers | Drug Master Files (DMF) | CEP

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API | Excipient name

Larotrectinib Sulfate

Synonyms

1223405-08-0, Loxo-101 sulfate, Arry-470 sulfate, Loxo-101 (sulfate), (s)-n-(5-((r)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide sulfate, Rdf76r62id

Cas Number

1223405-08-0

Unique Ingredient Identifier (UNII)

RDF76R62ID

About Larotrectinib Sulfate

Larotrectinib Sulfate is the sulfate salt form of larotrectinib, an orally available, tropomyosin receptor kinase (Trk) inhibitor, with potential antineoplastic activity. Upon administration, larotrectinib binds to Trk, thereby preventing neurotrophin-Trk interaction and Trk activation, which results in both the induction of cellular apoptosis and the inhibition of cell growth in tumors that overexpress Trk. Trk, a receptor tyrosine kinase activated by neurotrophins, is mutated in a variety of cancer cell types and plays an important role in tumor cell growth and survival.

Larotrectinib Sulfate Manufacturers

A Larotrectinib Sulfate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Larotrectinib Sulfate, including repackagers and relabelers. The FDA regulates Larotrectinib Sulfate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Larotrectinib Sulfate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Larotrectinib Sulfate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Larotrectinib Sulfate Suppliers

A Larotrectinib Sulfate supplier is an individual or a company that provides Larotrectinib Sulfate active pharmaceutical ingredient (API) or Larotrectinib Sulfate finished formulations upon request. The Larotrectinib Sulfate suppliers may include Larotrectinib Sulfate API manufacturers, exporters, distributors and traders.

click here to find a list of Larotrectinib Sulfate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Larotrectinib Sulfate Manufacturers | Traders | Suppliers

We have 5 companies offering Larotrectinib Sulfate

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Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

List of all Manufacturers, Suppliers & Exporters of Larotrectinib Sulfate API listed on PharmaCompass with details of regulatory filings