Looking for 120638-55-3 / Bromfenac Sodium Salt Sesquihydrate API manufacturers, exporters & distributors?
Bromfenac Sodium Salt Sesquihydrate manufacturers, exporters & distributors
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API | Excipient name
Bromfenac Sodium Salt Sesquihydrate
Synonyms
Bromfenac sodium sesquihydrate, 120638-55-3, Bromfenac sodium [usan], Bromfenac sodium hydrate, Bromsite, Bromfenac monosodium salt sesquihydrate
Unique Ingredient Identifier (UNII)
8ECV571Y37
About Bromfenac Sodium Salt Sesquihydrate
Bromfenac Sodium is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory activities. Upon ophthalmic administration, bromfenac binds to and inhibits the activity of cyclooxygenase II (COX II), an enzyme which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins (PG). By inhibiting PG formation, bromfenac is able to inhibit PG-induced inflammation, thereby preventing vasodilation, leukocytosis, disruption of the blood-aqueous humor barrier, an increase in vascular permeability and an increase in intraocular pressure (IOP).