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    Thallous chloride tl 201

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

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    2D Structure
    Also known as: Thallium-201 chloride, Allous chloride tl-201, Thallous chloride t1-201, (201)tlcl, (201-tl)thallous chloride, Thallium-201(1+) chloride
    Molecular Formula
    ClTl
    Molecular Weight
    236.42  g/mol
    InChI Key
    GBECUEIQVRDUKB-RYDPDVNUSA-M
    Thallous Chloride Tl-201 is the chloride salt form of thallium-201, a cyclotron produced isotope use in diagnostic imaging. Thallous chloride TI-201 accumulates in myocardial cells and other tissues in an analogous way as potassium, and can be evaluated as a function of blood flow. By scintigraphic means, areas with decreased blood flow, consisting of ischemic cells, can be visualized due to decreased uptake of TI-201 in contrast to areas with normal blood flow.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    chloro(201Tl)thallium-201
    2.1.2 InChI
    InChI=1S/ClH.Tl/h1H;/q;+1/p-1/i;1-3
    2.1.3 InChI Key
    GBECUEIQVRDUKB-RYDPDVNUSA-M
    2.1.4 Canonical SMILES
    Cl[Tl]
    2.1.5 Isomeric SMILES
    Cl[201Tl]
    2.2 Synonyms
    2.2.1 Depositor-Supplied Synonyms

    1. Thallium-201 Chloride

    2. Allous Chloride Tl-201

    3. Thallous Chloride T1-201

    4. (201)tlcl

    5. (201-tl)thallous Chloride

    6. Thallium-201(1+) Chloride

    7. Unii-3i8y076a0e

    8. Thallous Chloride (201tlcl)

    9. ((201)tl)thallium Monochloride

    10. Chebi:32213

    11. ((201)tl)thallium(i) Chloride

    12. ((201)tl)thallium(1+) Chloride

    13. Thallium Chloride ((sup 201)tlcl)

    14. Thallous Chloride Tl 201 [usan:usp]

    15. Thallium Chloride ((sup 201)tl) Injection

    16. Q27114831

    2.3 Create Date
    2007-04-03
    3 Chemical and Physical Properties
    Molecular Weight 236.42 g/mol
    Molecular Formula ClTl
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count0
    Rotatable Bond Count0
    Exact Mass235.9397 g/mol
    Monoisotopic Mass235.9397 g/mol
    Topological Polar Surface Area0 Ų
    Heavy Atom Count2
    Formal Charge0
    Complexity2
    Isotope Atom Count1
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameThallous chloride tl 201
    PubMed HealthThallous Chloride Tl 201 (Injection)
    Drug ClassesDiagnostic Agent, Radiopharmaceutical Imaging
    Active IngredientThallous chloride tl-201
    Dosage FormInjectable
    RouteInjection; Intravenous
    Strength1mci/ml; 2mci/ml
    Market StatusPrescription
    CompanyMallinckrodt; Lantheus Medcl; Ge Healthcare

    2 of 2  
    Drug NameThallous chloride tl 201
    PubMed HealthThallous Chloride Tl 201 (Injection)
    Drug ClassesDiagnostic Agent, Radiopharmaceutical Imaging
    Active IngredientThallous chloride tl-201
    Dosage FormInjectable
    RouteInjection; Intravenous
    Strength1mci/ml; 2mci/ml
    Market StatusPrescription
    CompanyMallinckrodt; Lantheus Medcl; Ge Healthcare

    5 Pharmacology and Biochemistry
    5.1 FDA Pharmacological Classification
    5.1.1 Pharmacological Classes
    Radiopharmaceutical Activity [MoA]; Radioactive Diagnostic Agent [EPC]