loader
Please Wait
Applying Filters...

Polpharma European CDMO Partner & API Manufacturer since 1951 Polpharma European CDMO Partner & API Manufacturer since 1951

X
menu

    Market Place

    Market Place

    Post Enquiry

    Post Enquiry
    menu

    Technical details about Tazobactam, learn more about the structure, uses, toxicity, action, side effects and more

    Client Email Product
    Menu

    Tazobactam

    APIs // Active Pharmaceutical Ingredients

    DEVELOPMENTS

    PRICE INFORMATION

    INTERMEDIATES

    DOSSIERs // Finished Dosage Forms

    DRUG PRODUCT COMPOSITION

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    GLOBAL SALES INFORMATION

    MARKET PLACE

    PATENTS

    REF. STANDARDS & IMPURITIES

    DIGITAL CONTENT

    PharmaCompass

    Bora Pharmaceuticals- Making success more certain.

    AbbVie CDMO has been working with global companies to develop, manufacture & scale biopharmaceutical products.

    2D Structure
    1. Also known as: Tazobactam sodium salt, 89785-84-2, Tazobactum sodium, Tazobactam sodium [usan], Cl-307579, Tazobactam (sodium)
    Molecular Formula
    C10H11N4NaO5S
    Molecular Weight
    322.28  g/mol
    InChI Key
    RFMIKMMOLPNEDG-QVUDESDKSA-M
    FDA UNII
    UXA545ABTT
    A penicillanic acid and sulfone derivative and potent BETA-LACTAMASE inhibitor that enhances the activity of other anti-bacterial agents against beta-lactamase producing bacteria.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-46-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
    2.1.2 InChI
    InChI=1S/C10H12N4O5S.Na/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19;/h2-3,7-8H,4-5H2,1H3,(H,16,17);/q;+1/p-1/t7-,8+,10+;/m1./s1
    2.1.3 InChI Key
    RFMIKMMOLPNEDG-QVUDESDKSA-M
    2.1.4 Canonical SMILES
    CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)[O-])CN3C=CN=N3.[Na+]
    2.1.5 Isomeric SMILES
    C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)[O-])CN3C=CN=N3.[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    UXA545ABTT
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Tazobactam

    2. Ytr 830

    3. Ytr 830h

    4. Ytr-830

    5. Ytr830

    2.3.2 Depositor-Supplied Synonyms

    1. Tazobactam Sodium Salt

    2. 89785-84-2

    3. Tazobactum Sodium

    4. Tazobactam Sodium [usan]

    5. Cl-307579

    6. Tazobactam (sodium)

    7. Ytr-830

    8. Tazobactam (as Sodium)

    9. Cl 307,579

    10. Uxa545abtt

    11. Chembl1439

    12. Cl 307579

    13. Chebi:85192

    14. 89785-84-2 (sodium)

    15. Ytr 830

    16. 2-alpha-methyl-2-beta-(1,2,3-triazol-1-ylmethyl)penam-3-alpha-carboxylic Acid Sodium Salt

    17. Dsstox_cid_26030

    18. Dsstox_rid_81299

    19. Dsstox_gsid_46030

    20. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3-methyl-7-oxo-3-(1h-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, Sodium Salt, (2s,3s,5r)-

    21. Sodium (2s,3s,5r)-3-methyl-7-oxo-3-(1h-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate, 4,4-dioxide

    22. Sodium;(2s,3s,5r)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

    23. Cas-89785-84-2

    24. Unii-uxa545abtt

    25. Tazobactum

    26. Ncgc00159340-02

    27. Schembl259991

    28. Tazobactam Sodium (jan/usan)

    29. Tazobactam Sodium [jan]

    30. Dtxsid8046030

    31. Tazobactam Sodium [vandf]

    32. Tazobactam Sodium [mart.]

    33. Yp-14

    34. Tazobactam Sodium [who-dd]

    35. Sodium (2s,3s,5r)-3-((1h-1,2,3-triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide

    36. Tazobactam Sodium Salt [mi]

    37. Tox21_111584

    38. Bdbm50157692

    39. Mfcd00917472

    40. Akos015962921

    41. Akos016843926

    42. Tox21_111584_1

    43. Cs-w009884

    44. Hy-w009168

    45. Tazobactam Sodium [orange Book]

    46. Zosyn Component Tazobactam Sodium

    47. Ncgc00159340-05

    48. Ac-18978

    49. Ac-32478

    50. As-56873

    51. Zerbaxa Component Tazobactam Sodium

    52. Tazobactam Sodium Salt, Analytical Standard

    53. Tazobactam Sodium Component Of Zosyn

    54. Tazobactam Sodium Component Of Zerbaxa

    55. D03707

    56. T-1446

    57. Tazobactam Sodium Salt, Beta-lactamase Inhibitor

    58. Q27158392

    59. Tazobactam Sodium Salt, Antibiotic For Culture Media Use Only

    60. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3-methyl-7-oxo-3-(1h-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, Sodium Salt, (2s-(2alpha,3beta,5alpha))-

    61. Sodium (2s,3s,5r)-3-methyl-4,4,7-trioxo-3-[(1h-1,2,3-triazol-1-yl)methyl]-4lambda(6)-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

    62. Sodium (2s,3s,5r)-3-methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate

    63. Sodium(2s,3s,5r)-3-((1h-1,2,3-triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate4,4-dioxide

    64. Sodium; (2s,3s,5r)-3-methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate

    2.4 Create Date
    2008-02-05
    3 Chemical and Physical Properties
    Molecular Weight 322.28 g/mol
    Molecular Formula C10H11N4NaO5S
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count7
    Rotatable Bond Count3
    Exact Mass322.03478492 g/mol
    Monoisotopic Mass322.03478492 g/mol
    Topological Polar Surface Area134 Ų
    Heavy Atom Count21
    Formal Charge0
    Complexity579
    Isotope Atom Count0
    Defined Atom Stereocenter Count3
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

    beta-Lactamase Inhibitors

    Endogenous substances and drugs that inhibit or block the activity of BETA-LACTAMASES. (See all compounds classified as beta-Lactamase Inhibitors.)

    Post Enquiry
    POST ENQUIRY