loader
Please Wait
Applying Filters...

Suanfarma Suanfarma

X
menu

    Market Place

    Market Place

    Post Enquiry

    Post Enquiry
    menu

    Technical details about Mitapivat, learn more about the structure, uses, toxicity, action, side effects and more

    Client Email Product
    Menu

    Mitapivat

    APIs // Active Pharmaceutical Ingredients

    DEVELOPMENTS

    DOSSIERs // Finished Dosage Forms

    GLOBAL SALES INFORMATION

    PATENTS

    DIGITAL CONTENT

    PharmaCompass

    Inke S.A: APIs manufacturing plant.

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    2D Structure
    1. Also known as: Ag-348 sulfate hydrate, Mitapivat sulfate [usan], N4jta67v3o, Pyrukynd, Ag-348 hemisulfate sesquihydrate, Mitapivat sulfate (usan)
    Molecular Formula
    C48H60N8O13S3
    Molecular Weight
    1053.2  g/mol
    InChI Key
    DMRIPASJCJRBMV-UHFFFAOYSA-N
    FDA UNII
    N4JTA67V3O
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N-[4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide;sulfuric acid;trihydrate
    2.1.2 InChI
    InChI=1S/2C24H26N4O3S.H2O4S.3H2O/c2*29-24(28-15-13-27(14-16-28)17-18-6-7-18)20-8-10-21(11-9-20)26-32(30,31)22-5-1-3-19-4-2-12-25-23(19)22;1-5(2,3)4;;;/h2*1-5,8-12,18,26H,6-7,13-17H2;(H2,1,2,3,4);3*1H2
    2.1.3 InChI Key
    DMRIPASJCJRBMV-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1CC1CN2CCN(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C4=CC=CC5=C4N=CC=C5.C1CC1CN2CCN(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C4=CC=CC5=C4N=CC=C5.O.O.O.OS(=O)(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    N4JTA67V3O
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 8-quinolinesulfonamide, N-(4-((4-(cyclopropylmethyl)-1-piperazinyl)carbonyl)phenyl)-

    2. Ag-348

    3. Mitapivat

    4. Mitapivat Hemisulfate Sesquihydrate

    5. N-(4-((4-(cyclopropylmethyl)-1-piperazinyl)carbonyl)phenyl)-8-quinolinesulfonamide

    6. N-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide

    7. Pyrukynd

    2.3.2 Depositor-Supplied Synonyms

    1. Ag-348 Sulfate Hydrate

    2. Mitapivat Sulfate [usan]

    3. N4jta67v3o

    4. Pyrukynd

    5. Ag-348 Hemisulfate Sesquihydrate

    6. Mitapivat Sulfate (usan)

    7. 2151847-10-6

    8. 8-quinolinesulfonamide, N-(4-((4-(cyclopropylmethyl)-1-piperazinyl)carbonyl)phenyl)-, Sulfate, Hydrate (2:1:3)

    9. N-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide Sulfate Hydrate (2:1:3)

    10. Unii-n4jta67v3o

    11. Chembl4297223

    12. Mitapivat Hemisulfate Sesquihydrate

    13. D11408

    2.4 Create Date
    2018-08-12
    3 Chemical and Physical Properties
    Molecular Weight 1053.2 g/mol
    Molecular Formula C48H60N8O13S3
    Hydrogen Bond Donor Count7
    Hydrogen Bond Acceptor Count19
    Rotatable Bond Count12
    Exact Mass1052.34419752 g/mol
    Monoisotopic Mass1052.34419752 g/mol
    Topological Polar Surface Area268 Ų
    Heavy Atom Count72
    Formal Charge0
    Complexity831
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count6
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Enzyme Activators

    Compounds or factors that act on a specific enzyme to increase its activity. (See all compounds classified as Enzyme Activators.)

    Post Enquiry
    POST ENQUIRY