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Technical details about Laam Hydrochloride, learn more about the structure, uses, toxicity, action, side effects and more

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2D Structure
1. Also known as: Laam hydrochloride, Levomethadyl acetate hcl, 43033-72-3, L-alpha-acetylmethadol hydrochloride, Levomethadyl acetate hydrochloride [usan], Mk790
Molecular Formula
C23H32ClNO2
Molecular Weight
390.0  g/mol
InChI Key
UXBPQRGCVJOTNT-COBSGTNCSA-N
FDA UNII
B54CW5KG52

A narcotic analgesic with a long onset and duration of action.
1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl] acetate;hydrochloride
2.1.2 InChI
InChI=1S/C23H31NO2.ClH/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21;/h7-16,18,22H,6,17H2,1-5H3;1H/t18-,22-;/m0./s1
2.1.3 InChI Key
UXBPQRGCVJOTNT-COBSGTNCSA-N
2.1.4 Canonical SMILES
CCC(C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C.Cl
2.1.5 Isomeric SMILES
CC[C@@H](C(C[C@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C.Cl
2.2 Other Identifiers
2.2.1 UNII
B54CW5KG52
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (3r,6r)-3-acetoxy-6-dimethylamino-4,4-diphenylheptane

2. 6-(dimethylamino)-4,4-diphenyl-3-heptanol Acetate

3. Acemethadone

4. Acetylmethadol

5. Alphacetylmethadol

6. Amidolacetate

7. Dimepheptanol

8. Laam

9. Levo Alpha Acetylmethadol

10. Levo-alpha-acetylmethadol

11. Levoacetylmethadol

12. Levomethadyl

13. Levomethadyl Acetate

14. Methadol

15. Methadyl Acetate

16. Orlaam

2.3.2 Depositor-Supplied Synonyms

1. Laam Hydrochloride

2. Levomethadyl Acetate Hcl

3. 43033-72-3

4. L-alpha-acetylmethadol Hydrochloride

5. Levomethadyl Acetate Hydrochloride [usan]

6. Mk790

7. B54cw5kg52

8. Mk-790

9. (-)-(3s,6s)-6-(dimethylamino)-4,4-diphenyl-3-heptanol Acetate (ester), Hydrochloride

10. (3s,6s)-6-(dimethylamino)-4,4-diphenylheptan-3-yl Acetate Hydrochloride

11. L-acetylmethadol Hydrochloride

12. Levomethadyl Acetate Hydrochloride (usan)

13. Ccris 3321

14. Levacetyl Methadol Hydrochloride

15. Laam-hcl

16. Alpha-l-acetylmethadol Hydrochloride

17. Mk 790

18. Unii-b54cw5kg52

19. Levacetylmethadol Hydrochloride

20. Orlaam (tn)

21. Schembl79093

22. Mls002320666

23. 6-dimethylamino-4,4-diphenyl-3-heptanolacetate.hcl

24. Chebi:6442

25. Chembl1200817

26. Dtxsid7020500

27. (1s,4s)-4-(dimethylamino)-1-ethyl-2,2-diphenylpentyl Acetate Hydrochloride

28. 3-heptanol, 6-(dimethylamino)-4,4-diphenyl-, Acetate (ester), Hydrochloride, (3s,6s)-(-)-

29. Benzeneethanol, Beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, Acetate (ester), Hydrochloride, (s-(r*,r*))-

30. Smr001338812

31. Laam Hydrochloride, >=98% (hplc), Solid

32. D00840

33. Levacetylmethadol Hydrochloride [mart.]

34. Levomethadyl Acetate Hydrochloride [mi]

35. Levomethadyl Acetate Hydrochloride [vandf]

36. Levomethadyl Acetate Hydrochloride [who-dd]

37. Q27274386

38. Levomethadyl Acetate Hydrochloride [orange Book]

39. 6-dimethylamino-4,4-diphenyl-3-heptanol Acetate.hcl

40. [(3s,6s)-6-(dimethylamino)-4,4-diphenylheptan-3-yl] Acetate;hydrochloride

41. Benzeneethanol, .beta.-(2-(dimethylamino)propyl)-.alpha.-ethyl-.beta.-phenyl-, Acetate (ester), Hydrochloride, (s-(r*,r*))-

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 390.0 g/mol
Molecular Formula C23H32ClNO2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count9
Exact Mass389.2121570 g/mol
Monoisotopic Mass389.2121570 g/mol
Topological Polar Surface Area29.5 Ų
Heavy Atom Count27
Formal Charge0
Complexity404
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Analgesics, Opioid

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)


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